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Journal Abstract Search


385 related items for PubMed ID: 19795500

  • 1. Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity.
    Tang KS, Suh SW, Alano CC, Shao Z, Hunt WT, Swanson RA, Anderson CM.
    Glia; 2010 Mar; 58(4):446-57. PubMed ID: 19795500
    [Abstract] [Full Text] [Related]

  • 2. NAD+ as a metabolic link between DNA damage and cell death.
    Ying W, Alano CC, Garnier P, Swanson RA.
    J Neurosci Res; 2010 Mar; 79(1-2):216-23. PubMed ID: 15562437
    [Abstract] [Full Text] [Related]

  • 3. Zinc inhibits astrocyte glutamate uptake by activation of poly(ADP-ribose) polymerase-1.
    Suh SW, Aoyama K, Alano CC, Anderson CM, Hamby AM, Swanson RA.
    Mol Med; 2007 Mar; 13(7-8):344-9. PubMed ID: 17728843
    [Abstract] [Full Text] [Related]

  • 4. Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.
    Kauppinen TM, Gan L, Swanson RA.
    Biochim Biophys Acta; 2013 Aug; 1833(8):1985-91. PubMed ID: 23597856
    [Abstract] [Full Text] [Related]

  • 5. NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes.
    Ying W, Garnier P, Swanson RA.
    Biochem Biophys Res Commun; 2003 Sep 05; 308(4):809-13. PubMed ID: 12927790
    [Abstract] [Full Text] [Related]

  • 6. The role of NADPH oxidase and neuronal nitric oxide synthase in zinc-induced poly(ADP-ribose) polymerase activation and cell death in cortical culture.
    Kim YH, Koh JY.
    Exp Neurol; 2002 Oct 05; 177(2):407-18. PubMed ID: 12429187
    [Abstract] [Full Text] [Related]

  • 7. PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent.
    Ethier C, Tardif M, Arul L, Poirier GG.
    PLoS One; 2012 Oct 05; 7(10):e47978. PubMed ID: 23110147
    [Abstract] [Full Text] [Related]

  • 8. Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death.
    Ying W, Sevigny MB, Chen Y, Swanson RA.
    Proc Natl Acad Sci U S A; 2001 Oct 09; 98(21):12227-32. PubMed ID: 11593040
    [Abstract] [Full Text] [Related]

  • 9. Role of poly(ADP-ribose) polymerase in rapid intracellular acidification induced by alkylating DNA damage.
    Affar el B, Shah RG, Dallaire AK, Castonguay V, Shah GM.
    Proc Natl Acad Sci U S A; 2002 Jan 08; 99(1):245-50. PubMed ID: 11756665
    [Abstract] [Full Text] [Related]

  • 10. Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake.
    Suzuki E, Okuda H, Nishida K, Fujimoto S, Nagasawa K.
    Life Sci; 2010 Apr 24; 86(17-18):676-82. PubMed ID: 20188745
    [Abstract] [Full Text] [Related]

  • 11. Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction.
    Cipriani G, Rapizzi E, Vannacci A, Rizzuto R, Moroni F, Chiarugi A.
    J Biol Chem; 2005 Apr 29; 280(17):17227-34. PubMed ID: 15750180
    [Abstract] [Full Text] [Related]

  • 12. NAD(+) influx through connexin hemichannels prevents poly(ADP-ribose) polymerase-mediated astrocyte death.
    Okuda H, Nishida K, Higashi Y, Nagasawa K.
    Life Sci; 2013 Apr 19; 92(13):808-14. PubMed ID: 23454167
    [Abstract] [Full Text] [Related]

  • 13. Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis.
    Andrabi SA, Umanah GK, Chang C, Stevens DA, Karuppagounder SS, Gagné JP, Poirier GG, Dawson VL, Dawson TM.
    Proc Natl Acad Sci U S A; 2014 Jul 15; 111(28):10209-14. PubMed ID: 24987120
    [Abstract] [Full Text] [Related]

  • 14. Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.
    Pogrebniak A, Schemainda I, Pelka-Fleischer R, Nüssler V, Hasmann M.
    Eur J Med Res; 2003 Oct 22; 8(10):438-50. PubMed ID: 14594650
    [Abstract] [Full Text] [Related]

  • 15. Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP): prevention by the poly(ADP-ribose) polymerase inhibitor, benzamide.
    Cosi C, Marien M.
    Brain Res; 1998 Oct 26; 809(1):58-67. PubMed ID: 9795136
    [Abstract] [Full Text] [Related]

  • 16. Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes.
    Ying W, Chen Y, Alano CC, Swanson RA.
    J Cereb Blood Flow Metab; 2002 Jul 26; 22(7):774-9. PubMed ID: 12142562
    [Abstract] [Full Text] [Related]

  • 17. Vincristine attenuates N-methyl-N'-nitro-N-nitrosoguanidine-induced poly-(ADP) ribose polymerase activity in cardiomyocytes.
    Zhang J, Chatterjee K, Alano CC, Kalinowski MA, Honbo N, Karliner JS.
    J Cardiovasc Pharmacol; 2010 Mar 26; 55(3):219-26. PubMed ID: 20375713
    [Abstract] [Full Text] [Related]

  • 18. AMPK mediates a pro-survival autophagy downstream of PARP-1 activation in response to DNA alkylating agents.
    Zhou J, Ng S, Huang Q, Wu YT, Li Z, Yao SQ, Shen HM.
    FEBS Lett; 2013 Jan 16; 587(2):170-7. PubMed ID: 23201261
    [Abstract] [Full Text] [Related]

  • 19. Glucose deprivation converts poly(ADP-ribose) polymerase-1 hyperactivation into a transient energy-producing process.
    Buonvicino D, Formentini L, Cipriani G, Chiarugi A.
    J Biol Chem; 2013 Dec 20; 288(51):36530-7. PubMed ID: 24194524
    [Abstract] [Full Text] [Related]

  • 20. Neither energy collapse nor transcription underlie in vitro neurotoxicity of poly(ADP-ribose) polymerase hyper-activation.
    Fossati S, Cipriani G, Moroni F, Chiarugi A.
    Neurochem Int; 2007 Jan 20; 50(1):203-10. PubMed ID: 17052800
    [Abstract] [Full Text] [Related]


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