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Journal Abstract Search

520 related items for PubMed ID: 19796173

  • 1. Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
    Göckler N, Jofre G, Papadopoulos C, Soppa U, Tejedor FJ, Becker W.
    FEBS J; 2009 Nov; 276(21):6324-37. PubMed ID: 19796173
    [Abstract] [Full Text] [Related]

  • 2. DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine.
    Seifert A, Allan LA, Clarke PR.
    FEBS J; 2008 Dec; 275(24):6268-80. PubMed ID: 19016842
    [Abstract] [Full Text] [Related]

  • 3. Mechanism of dual specificity kinase activity of DYRK1A.
    Walte A, Rüben K, Birner-Gruenberger R, Preisinger C, Bamberg-Lemper S, Hilz N, Bracher F, Becker W.
    FEBS J; 2013 Sep; 280(18):4495-511. PubMed ID: 23809146
    [Abstract] [Full Text] [Related]

  • 4. The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells.
    Egusa H, Doi M, Saeki M, Fukuyasu S, Akashi Y, Yokota Y, Yatani H, Kamisaki Y.
    Bone; 2011 Aug; 49(2):264-74. PubMed ID: 21504804
    [Abstract] [Full Text] [Related]

  • 5. Activation, regulation, and inhibition of DYRK1A.
    Becker W, Sippl W.
    FEBS J; 2011 Jan; 278(2):246-56. PubMed ID: 21126318
    [Abstract] [Full Text] [Related]

  • 6. Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.
    Adayev T, Chen-Hwang MC, Murakami N, Lee E, Bolton DC, Hwang YW.
    Biochemistry; 2007 Jun 26; 46(25):7614-24. PubMed ID: 17536841
    [Abstract] [Full Text] [Related]

  • 7. Library-based discovery of DYRK1A/CLK1 inhibitors from natural product extracts.
    Grabher P, Durieu E, Kouloura E, Halabalaki M, Skaltsounis LA, Meijer L, Hamburger M, Potterat O.
    Planta Med; 2012 Jun 26; 78(10):951-6. PubMed ID: 22673832
    [Abstract] [Full Text] [Related]

  • 8. Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.
    Rüben K, Wurzlbauer A, Walte A, Sippl W, Bracher F, Becker W.
    PLoS One; 2015 Jun 26; 10(7):e0132453. PubMed ID: 26192590
    [Abstract] [Full Text] [Related]

  • 9. Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A).
    Adayev T, Wegiel J, Hwang YW.
    Arch Biochem Biophys; 2011 Mar 15; 507(2):212-8. PubMed ID: 21185805
    [Abstract] [Full Text] [Related]

  • 10. Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice.
    Mazur-Kolecka B, Golabek A, Kida E, Rabe A, Hwang YW, Adayev T, Wegiel J, Flory M, Kaczmarski W, Marchi E, Frackowiak J.
    J Neurosci Res; 2012 May 15; 90(5):999-1010. PubMed ID: 22252917
    [Abstract] [Full Text] [Related]

  • 11. Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
    Ryoo SR, Cho HJ, Lee HW, Jeong HK, Radnaabazar C, Kim YS, Kim MJ, Son MY, Seo H, Chung SH, Song WJ.
    J Neurochem; 2008 Mar 15; 104(5):1333-44. PubMed ID: 18005339
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.
    Liu W, Liu X, Tian L, Gao Y, Liu W, Chen H, Jiang X, Xu Z, Ding H, Zhao Q.
    Eur J Med Chem; 2021 Oct 15; 222():113554. PubMed ID: 34098466
    [Abstract] [Full Text] [Related]

  • 13. QSAR analysis of pyrazolidine-3,5-diones derivatives as Dyrk1A inhibitors.
    Koo KA, Kim ND, Chon YS, Jung MS, Lee BJ, Kim JH, Song WJ.
    Bioorg Med Chem Lett; 2009 Apr 15; 19(8):2324-8. PubMed ID: 19282176
    [Abstract] [Full Text] [Related]

  • 14. A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
    Coutadeur S, Benyamine H, Delalonde L, de Oliveira C, Leblond B, Foucourt A, Besson T, Casagrande AS, Taverne T, Girard A, Pando MP, Désiré L.
    J Neurochem; 2015 May 15; 133(3):440-51. PubMed ID: 25556849
    [Abstract] [Full Text] [Related]

  • 15. Regulation of Dyrk1A kinase activity by 14-3-3.
    Kim D, Won J, Shin DW, Kang J, Kim YJ, Choi SY, Hwang MK, Jeong BW, Kim GS, Joe CO, Chung SH, Song WJ.
    Biochem Biophys Res Commun; 2004 Oct 15; 323(2):499-504. PubMed ID: 15369779
    [Abstract] [Full Text] [Related]

  • 16. p38alpha- and DYRK1A-dependent phosphorylation of caspase-9 at an inhibitory site in response to hyperosmotic stress.
    Seifert A, Clarke PR.
    Cell Signal; 2009 Nov 15; 21(11):1626-33. PubMed ID: 19586613
    [Abstract] [Full Text] [Related]

  • 17. Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome.
    Park J, Yang EJ, Yoon JH, Chung KC.
    Mol Cell Neurosci; 2007 Oct 15; 36(2):270-9. PubMed ID: 17720532
    [Abstract] [Full Text] [Related]

  • 18. Dual-specificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A) interacts with the phytanoyl-CoA alpha-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein.
    Bescond M, Rahmani Z.
    Int J Biochem Cell Biol; 2005 Apr 15; 37(4):775-83. PubMed ID: 15694837
    [Abstract] [Full Text] [Related]

  • 19. Overexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosome.
    Funakoshi E, Hori T, Haraguchi T, Hiraoka Y, Kudoh J, Shimizu N, Ito F.
    BMC Cell Biol; 2003 Sep 10; 4():12. PubMed ID: 12964950
    [Abstract] [Full Text] [Related]

  • 20. DYRK1A stabilizes HPV16E7 oncoprotein through phosphorylation of the threonine 5 and threonine 7 residues.
    Liang YJ, Chang HS, Wang CY, Yu WC.
    Int J Biochem Cell Biol; 2008 Sep 10; 40(11):2431-41. PubMed ID: 18468476
    [Abstract] [Full Text] [Related]

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