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398 related items for PubMed ID: 19804829

  • 1. 1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice.
    Luongo L, Palazzo E, Tambaro S, Giordano C, Gatta L, Scafuro MA, Rossi FS, Lazzari P, Pani L, de Novellis V, Malcangio M, Maione S.
    Neurobiol Dis; 2010 Jan; 37(1):177-85. PubMed ID: 19804829
    [Abstract] [Full Text] [Related]

  • 2. Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain.
    Toth CC, Jedrzejewski NM, Ellis CL, Frey WH.
    Mol Pain; 2010 Mar 17; 6():16. PubMed ID: 20236533
    [Abstract] [Full Text] [Related]

  • 3. CB2 receptor-mediated antihyperalgesia: possible direct involvement of neural mechanisms.
    Beltramo M, Bernardini N, Bertorelli R, Campanella M, Nicolussi E, Fredduzzi S, Reggiani A.
    Eur J Neurosci; 2006 Mar 17; 23(6):1530-8. PubMed ID: 16553616
    [Abstract] [Full Text] [Related]

  • 4. Direct evidence for spinal cord microglia in the development of a neuropathic pain-like state in mice.
    Narita M, Yoshida T, Nakajima M, Narita M, Miyatake M, Takagi T, Yajima Y, Suzuki T.
    J Neurochem; 2006 Jun 17; 97(5):1337-48. PubMed ID: 16606373
    [Abstract] [Full Text] [Related]

  • 5. Gabapentin reverses microglial activation in the spinal cord of streptozotocin-induced diabetic rats.
    Wodarski R, Clark AK, Grist J, Marchand F, Malcangio M.
    Eur J Pain; 2009 Sep 17; 13(8):807-11. PubMed ID: 18977160
    [Abstract] [Full Text] [Related]

  • 6. A role for cannabinoid receptors, but not endogenous opioids, in the antinociceptive activity of the CB2-selective agonist, GW405833.
    Whiteside GT, Gottshall SL, Boulet JM, Chaffer SM, Harrison JE, Pearson MS, Turchin PI, Mark L, Garrison AE, Valenzano KJ.
    Eur J Pharmacol; 2005 Dec 28; 528(1-3):65-72. PubMed ID: 16316650
    [Abstract] [Full Text] [Related]

  • 7. Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia.
    Wen YR, Suter MR, Ji RR, Yeh GC, Wu YS, Wang KC, Kohno T, Sun WZ, Wang CC.
    Anesthesiology; 2009 Jan 28; 110(1):155-65. PubMed ID: 19104183
    [Abstract] [Full Text] [Related]

  • 8. The role of nitric oxide in the local antiallodynic and antihyperalgesic effects and expression of delta-opioid and cannabinoid-2 receptors during neuropathic pain in mice.
    Hervera A, Negrete R, Leánez S, Martín-Campos J, Pol O.
    J Pharmacol Exp Ther; 2010 Sep 01; 334(3):887-96. PubMed ID: 20498253
    [Abstract] [Full Text] [Related]

  • 9. Characterization of chronic constriction of the saphenous nerve, a model of neuropathic pain in mice showing rapid molecular and electrophysiological changes.
    Walczak JS, Pichette V, Leblond F, Desbiens K, Beaulieu P.
    J Neurosci Res; 2006 May 15; 83(7):1310-22. PubMed ID: 16511871
    [Abstract] [Full Text] [Related]

  • 10. Spinal microglial proliferation is evident in a rat model of painful disc herniation both in the presence of behavioral hypersensitivity and following minocycline treatment sufficient to attenuate allodynia.
    Rothman SM, Guarino BB, Winkelstein BA.
    J Neurosci Res; 2009 Sep 15; 87(12):2709-17. PubMed ID: 19382225
    [Abstract] [Full Text] [Related]

  • 11. The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior.
    Colburn RW, Rickman AJ, DeLeo JA.
    Exp Neurol; 1999 Jun 15; 157(2):289-304. PubMed ID: 10364441
    [Abstract] [Full Text] [Related]

  • 12. Contralateral neuropathic pain and neuropathology in dorsal root ganglion and spinal cord following hemilateral nerve injury in rats.
    Hatashita S, Sekiguchi M, Kobayashi H, Konno S, Kikuchi S.
    Spine (Phila Pa 1976); 2008 May 20; 33(12):1344-51. PubMed ID: 18496347
    [Abstract] [Full Text] [Related]

  • 13. The galactosylation of N(ω)-nitro-L-arginine enhances its anti-nocifensive or anti-allodynic effects by targeting glia in healthy and neuropathic mice.
    Giordano C, Siniscalco D, Melisi D, Luongo L, Curcio A, Soukupova M, Palazzo E, Marabese I, De Chiaro M, Rimoli MG, Rossi F, Maione S, de Novellis V.
    Eur J Pharmacol; 2011 Apr 10; 656(1-3):52-62. PubMed ID: 21296071
    [Abstract] [Full Text] [Related]

  • 14. Antinociceptive effects of the non-selective cannabinoid receptor agonist CP 55,940 are absent in CB1(-/-) and not CB2(-/-) mice in models of acute and persistent pain.
    Sain NM, Liang A, Kane SA, Urban MO.
    Neuropharmacology; 2009 Sep 10; 57(3):235-41. PubMed ID: 19538975
    [Abstract] [Full Text] [Related]

  • 15. Selective activation of cannabinoid CB2 receptors suppresses hyperalgesia evoked by intradermal capsaicin.
    Hohmann AG, Farthing JN, Zvonok AM, Makriyannis A.
    J Pharmacol Exp Ther; 2004 Feb 10; 308(2):446-53. PubMed ID: 14610224
    [Abstract] [Full Text] [Related]

  • 16. Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide.
    Murineddu G, Lazzari P, Ruiu S, Sanna A, Loriga G, Manca I, Falzoi M, Dessì C, Curzu MM, Chelucci G, Pani L, Pinna GA.
    J Med Chem; 2006 Dec 14; 49(25):7502-12. PubMed ID: 17149879
    [Abstract] [Full Text] [Related]

  • 17. Ketamine depresses toll-like receptor 3 signaling in spinal microglia in a rat model of neuropathic pain.
    Mei XP, Zhou Y, Wang W, Tang J, Wang W, Zhang H, Xu LX, Li YQ.
    Neurosignals; 2011 Dec 14; 19(1):44-53. PubMed ID: 21389680
    [Abstract] [Full Text] [Related]

  • 18. Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons.
    Wotherspoon G, Fox A, McIntyre P, Colley S, Bevan S, Winter J.
    Neuroscience; 2005 Dec 14; 135(1):235-45. PubMed ID: 16084654
    [Abstract] [Full Text] [Related]

  • 19. Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain.
    Qu XX, Cai J, Li MJ, Chi YN, Liao FF, Liu FY, Wan Y, Han JS, Xing GG.
    Exp Neurol; 2009 Feb 14; 215(2):298-307. PubMed ID: 19046970
    [Abstract] [Full Text] [Related]

  • 20. Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli.
    Maresz K, Carrier EJ, Ponomarev ED, Hillard CJ, Dittel BN.
    J Neurochem; 2005 Oct 14; 95(2):437-45. PubMed ID: 16086683
    [Abstract] [Full Text] [Related]

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