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264 related items for PubMed ID: 19805354

  • 1. Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6.
    Gibbs A, Schwartzman J, Deng V, Alumkal J.
    Proc Natl Acad Sci U S A; 2009 Sep 29; 106(39):16663-8. PubMed ID: 19805354
    [Abstract] [Full Text] [Related]

  • 2. HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer.
    Ai J, Wang Y, Dar JA, Liu J, Liu L, Nelson JB, Wang Z.
    Mol Endocrinol; 2009 Dec 29; 23(12):1963-72. PubMed ID: 19855091
    [Abstract] [Full Text] [Related]

  • 3. Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function.
    Basak S, Pookot D, Noonan EJ, Dahiya R.
    Mol Cancer Ther; 2008 Oct 29; 7(10):3195-202. PubMed ID: 18852123
    [Abstract] [Full Text] [Related]

  • 4. Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells.
    Clarke JD, Hsu A, Yu Z, Dashwood RH, Ho E.
    Mol Nutr Food Res; 2011 Jul 29; 55(7):999-1009. PubMed ID: 21374800
    [Abstract] [Full Text] [Related]

  • 5. Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease Heat Shock Protein 90 and Androgen Receptor Levels and Inhibit Viability in Enzalutamide-Resistant C4-2 Prostate Cancer Cells.
    Rosati R, Chen B, Patki M, McFall T, Ou S, Heath E, Ratnam M, Qin Z.
    Mol Pharmacol; 2016 Sep 29; 90(3):225-37. PubMed ID: 27382012
    [Abstract] [Full Text] [Related]

  • 6. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells.
    Kim SH, Singh SV.
    Mol Cancer Ther; 2009 Jul 29; 8(7):1946-54. PubMed ID: 19584240
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.
    Bali P, Pranpat M, Bradner J, Balasis M, Fiskus W, Guo F, Rocha K, Kumaraswamy S, Boyapalle S, Atadja P, Seto E, Bhalla K.
    J Biol Chem; 2005 Jul 22; 280(29):26729-34. PubMed ID: 15937340
    [Abstract] [Full Text] [Related]

  • 8. PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer.
    Gravina GL, Marampon F, Muzi P, Mancini A, Piccolella M, Negri-Cesi P, Motta M, Lenzi A, Di Cesare E, Tombolini V, Jannini EA, Festuccia C.
    Endocr Relat Cancer; 2013 Jun 22; 20(3):321-37. PubMed ID: 23507703
    [Abstract] [Full Text] [Related]

  • 9. HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells.
    Rao R, Fiskus W, Yang Y, Lee P, Joshi R, Fernandez P, Mandawat A, Atadja P, Bradner JE, Bhalla K.
    Blood; 2008 Sep 01; 112(5):1886-93. PubMed ID: 18591380
    [Abstract] [Full Text] [Related]

  • 10. The effect of sulforaphane on histone deacetylase activity in keratinocytes: Differences between in vitro and in vivo analyses.
    Dickinson SE, Rusche JJ, Bec SL, Horn DJ, Janda J, Rim SH, Smith CL, Bowden GT.
    Mol Carcinog; 2015 Nov 01; 54(11):1513-20. PubMed ID: 25307283
    [Abstract] [Full Text] [Related]

  • 11. HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.
    Kovacs JJ, Murphy PJ, Gaillard S, Zhao X, Wu JT, Nicchitta CV, Yoshida M, Toft DO, Pratt WB, Yao TP.
    Mol Cell; 2005 May 27; 18(5):601-7. PubMed ID: 15916966
    [Abstract] [Full Text] [Related]

  • 12. Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention.
    Ho E, Clarke JD, Dashwood RH.
    J Nutr; 2009 Dec 27; 139(12):2393-6. PubMed ID: 19812222
    [Abstract] [Full Text] [Related]

  • 13. Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.
    Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E.
    Carcinogenesis; 2006 Apr 27; 27(4):811-9. PubMed ID: 16280330
    [Abstract] [Full Text] [Related]

  • 14. Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.
    Rajendran P, Delage B, Dashwood WM, Yu TW, Wuth B, Williams DE, Ho E, Dashwood RH.
    Mol Cancer; 2011 May 30; 10():68. PubMed ID: 21624135
    [Abstract] [Full Text] [Related]

  • 15. Potent induction of phase 2 enzymes in human prostate cells by sulforaphane.
    Brooks JD, Paton VG, Vidanes G.
    Cancer Epidemiol Biomarkers Prev; 2001 Sep 30; 10(9):949-54. PubMed ID: 11535546
    [Abstract] [Full Text] [Related]

  • 16. FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells.
    Ni L, Yang CS, Gioeli D, Frierson H, Toft DO, Paschal BM.
    Mol Cell Biol; 2010 Mar 30; 30(5):1243-53. PubMed ID: 20048054
    [Abstract] [Full Text] [Related]

  • 17. Histone Deacetylase 6-Controlled Hsp90 Acetylation Significantly Alters Mineralocorticoid Receptor Subcellular Dynamics But Not its Transcriptional Activity.
    Jiménez-Canino R, Lorenzo-Díaz F, Jaisser F, Farman N, Giraldez T, Alvarez de la Rosa D.
    Endocrinology; 2016 Jun 30; 157(6):2515-32. PubMed ID: 27100623
    [Abstract] [Full Text] [Related]

  • 18. Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor.
    Gaughan L, Logan IR, Cook S, Neal DE, Robson CN.
    J Biol Chem; 2002 Jul 19; 277(29):25904-13. PubMed ID: 11994312
    [Abstract] [Full Text] [Related]

  • 19. Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate cancer.
    Welsbie DS, Xu J, Chen Y, Borsu L, Scher HI, Rosen N, Sawyers CL.
    Cancer Res; 2009 Feb 01; 69(3):958-66. PubMed ID: 19176386
    [Abstract] [Full Text] [Related]

  • 20. Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention.
    Wang L, Liu D, Ahmed T, Chung FL, Conaway C, Chiao JW.
    Int J Oncol; 2004 Jan 01; 24(1):187-92. PubMed ID: 14654956
    [Abstract] [Full Text] [Related]

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