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211 related items for PubMed ID: 1981716

  • 1. Metabolism and cytotoxicity of acetaminophen in hepatocyte cultures from rat, rabbit, dog, and monkey.
    Smolarek TA, Higgins CV, Amacher DE.
    Drug Metab Dispos; 1990; 18(5):659-63. PubMed ID: 1981716
    [Abstract] [Full Text] [Related]

  • 2. Interspecies differences in acetaminophen sensitivity of human, rat, and mouse primary hepatocytes.
    Jemnitz K, Veres Z, Monostory K, Kóbori L, Vereczkey L.
    Toxicol In Vitro; 2008 Jun; 22(4):961-7. PubMed ID: 18346862
    [Abstract] [Full Text] [Related]

  • 3. Metabolism and cytotoxicity of acetaminophen in hepatocytes isolated from resistant and susceptible species.
    Green CE, Dabbs JE, Tyson CA.
    Toxicol Appl Pharmacol; 1984 Oct; 76(1):139-49. PubMed ID: 6484984
    [Abstract] [Full Text] [Related]

  • 4. Comparative metabolism of tolbutamide by isolated hepatocytes from rat, rabbit, dog, and squirrel monkey.
    Gee SJ, Green CE, Tyson CA.
    Drug Metab Dispos; 1984 Oct; 12(2):174-8. PubMed ID: 6144482
    [Abstract] [Full Text] [Related]

  • 5. The target portion of acetaminophen induced hepatotoxicity in rats: modification by thiol compounds.
    Hirayama C, Murawaki Y, Yamada S, Aoto Y, Ikeda F.
    Res Commun Chem Pathol Pharmacol; 1983 Dec; 42(3):431-48. PubMed ID: 6665301
    [Abstract] [Full Text] [Related]

  • 6. Acute acetaminophen toxicity in transgenic mice with elevated hepatic glutathione.
    Rzucidlo SJ, Bounous DI, Jones DP, Brackett BG.
    Vet Hum Toxicol; 2000 Jun; 42(3):146-50. PubMed ID: 10839317
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of temelastine (SK&F 93944) in hepatocytes from rat, dog, cynomolgus monkey and man.
    Oldham HG, Standring P, Norman SJ, Blake TJ, Beattie I, Cox PJ, Chenery RJ.
    Drug Metab Dispos; 1990 Jun; 18(2):146-52. PubMed ID: 1971564
    [Abstract] [Full Text] [Related]

  • 8. Sex-related differences in mouse renal metabolism and toxicity of acetaminophen.
    Hu JJ, Lee MJ, Vapiwala M, Reuhl K, Thomas PE, Yang CS.
    Toxicol Appl Pharmacol; 1993 Sep; 122(1):16-26. PubMed ID: 8378930
    [Abstract] [Full Text] [Related]

  • 9. Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity.
    Rogers SA, Gale KC, Newton JF, Dent JG, Leonard TB.
    J Pharmacol Exp Ther; 1988 Jun; 245(3):887-94. PubMed ID: 3133464
    [Abstract] [Full Text] [Related]

  • 10. Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites.
    Kostrubsky SE, Strom SC, Ellis E, Nelson SD, Mutlib AE.
    Chem Res Toxicol; 2007 Oct; 20(10):1503-12. PubMed ID: 17900172
    [Abstract] [Full Text] [Related]

  • 11. Acetaminophen metabolism, cytotoxicity, and genotoxicity in rat primary hepatocyte cultures.
    Milam KM, Byard JL.
    Toxicol Appl Pharmacol; 1985 Jun 30; 79(2):342-7. PubMed ID: 3923657
    [Abstract] [Full Text] [Related]

  • 12. Antioxidative and hepatoprotective effects of magnolol on acetaminophen-induced liver damage in rats.
    Chen YH, Lin FY, Liu PL, Huang YT, Chiu JH, Chang YC, Man KM, Hong CY, Ho YY, Lai MT.
    Arch Pharm Res; 2009 Feb 30; 32(2):221-8. PubMed ID: 19280152
    [Abstract] [Full Text] [Related]

  • 13. Kava extract, an herbal alternative for anxiety relief, potentiates acetaminophen-induced cytotoxicity in rat hepatic cells.
    Yang X, Salminen WF.
    Phytomedicine; 2011 May 15; 18(7):592-600. PubMed ID: 21397479
    [Abstract] [Full Text] [Related]

  • 14. Metabolism of para-aminophenol by rat hepatocytes.
    Yan Z, Nikelly JG, Killmer L, Tarloff JB.
    Drug Metab Dispos; 2000 Aug 15; 28(8):880-6. PubMed ID: 10901695
    [Abstract] [Full Text] [Related]

  • 15. Metabolism and excretion of a glutathione conjugate of acetaminophen in the isolated perfused rat kidney.
    Newton JF, Hoefle D, Gemborys MW, Mudge GH, Hook JB.
    J Pharmacol Exp Ther; 1986 May 15; 237(2):519-24. PubMed ID: 2871175
    [Abstract] [Full Text] [Related]

  • 16. Comparison of amphetamine metabolism using isolated hepatocytes from five species including human.
    Green CE, LeValley SE, Tyson CA.
    J Pharmacol Exp Ther; 1986 Jun 15; 237(3):931-6. PubMed ID: 3712286
    [Abstract] [Full Text] [Related]

  • 17. Comparison of tacrine-induced cytotoxicity in primary cultures of rat, mouse, monkey, dog, rabbit, and human hepatocytes.
    Monteith DK, Theiss JC.
    Drug Chem Toxicol; 1996 Jun 15; 19(1-2):59-70. PubMed ID: 8804553
    [Abstract] [Full Text] [Related]

  • 18. Spontaneous chemiluminescence production, lipid peroxidation, and covalent binding in rat hepatocytes exposed to acetaminophen.
    Minamide Y, Horie T, Tomaru A, Awazu S.
    J Pharm Sci; 1998 May 15; 87(5):640-6. PubMed ID: 9572917
    [Abstract] [Full Text] [Related]

  • 19. Transport of acetaminophen conjugates in isolated rat hepatocytes.
    Iida S, Mizuma T, Sakuma N, Hayashi M, Awazu S.
    Drug Metab Dispos; 1989 May 15; 17(3):341-4. PubMed ID: 2568918
    [Abstract] [Full Text] [Related]

  • 20. Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of acetaminophen-glutathione adducts.
    Manautou JE, Tveit A, Hoivik DJ, Khairallah EA, Cohen SD.
    Toxicol Appl Pharmacol; 1996 Sep 15; 140(1):30-8. PubMed ID: 8806867
    [Abstract] [Full Text] [Related]

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