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306 related items for PubMed ID: 19821497

  • 1. Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2.
    Blechacz BR, Smoot RL, Bronk SF, Werneburg NW, Sirica AE, Gores GJ.
    Hepatology; 2009 Dec; 50(6):1861-70. PubMed ID: 19821497
    [Abstract] [Full Text] [Related]

  • 2. Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3.
    Gu FM, Li QL, Gao Q, Jiang JH, Huang XY, Pan JF, Fan J, Zhou J.
    World J Gastroenterol; 2011 Sep 14; 17(34):3922-32. PubMed ID: 22025881
    [Abstract] [Full Text] [Related]

  • 3. Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells.
    Sugiyama H, Onuki K, Ishige K, Baba N, Ueda T, Matsuda S, Takeuchi K, Onodera M, Nakanuma Y, Yamato M, Yamamoto M, Hyodo I, Shoda J.
    J Gastroenterol; 2011 Jun 14; 46(6):779-89. PubMed ID: 21331764
    [Abstract] [Full Text] [Related]

  • 4. Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma.
    Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF.
    J Hepatol; 2011 Nov 14; 55(5):1041-8. PubMed ID: 21354226
    [Abstract] [Full Text] [Related]

  • 5. Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells.
    Huang S, Sinicrope FA.
    Mol Cancer Ther; 2010 Mar 14; 9(3):742-50. PubMed ID: 20197401
    [Abstract] [Full Text] [Related]

  • 6. Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3.
    Yang F, Brown C, Buettner R, Hedvat M, Starr R, Scuto A, Schroeder A, Jensen M, Jove R.
    Mol Cancer Ther; 2010 Apr 14; 9(4):953-62. PubMed ID: 20371721
    [Abstract] [Full Text] [Related]

  • 7. Sorafenib induces apoptosis in HL60 cells by inhibiting Src kinase-mediated STAT3 phosphorylation.
    Zhao W, Zhang T, Qu B, Wu X, Zhu X, Meng F, Gu Y, Shu Y, Shen Y, Sun Y, Xu Q.
    Anticancer Drugs; 2011 Jan 14; 22(1):79-88. PubMed ID: 20881478
    [Abstract] [Full Text] [Related]

  • 8. Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis.
    Yang F, Jove V, Buettner R, Xin H, Wu J, Wang Y, Nam S, Xu Y, Ara T, DeClerck YA, Seeger R, Yu H, Jove R.
    Cancer Biol Ther; 2012 May 14; 13(7):534-41. PubMed ID: 22406995
    [Abstract] [Full Text] [Related]

  • 9. Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas.
    Yang F, Van Meter TE, Buettner R, Hedvat M, Liang W, Kowolik CM, Mepani N, Mirosevich J, Nam S, Chen MY, Tye G, Kirschbaum M, Jove R.
    Mol Cancer Ther; 2008 Nov 14; 7(11):3519-26. PubMed ID: 19001435
    [Abstract] [Full Text] [Related]

  • 10. Sorafenib downregulates ERK/Akt and STAT3 survival pathways and induces apoptosis in a human neuroblastoma cell line.
    Chai H, Luo AZ, Weerasinghe P, Brown RE.
    Int J Clin Exp Pathol; 2010 Apr 23; 3(4):408-15. PubMed ID: 20490331
    [Abstract] [Full Text] [Related]

  • 11. Survey of activated kinase proteins reveals potential targets for cholangiocarcinoma treatment.
    Dokduang H, Juntana S, Techasen A, Namwat N, Yongvanit P, Khuntikeo N, Riggins GJ, Loilome W.
    Tumour Biol; 2013 Dec 23; 34(6):3519-28. PubMed ID: 23812726
    [Abstract] [Full Text] [Related]

  • 12. Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3.
    Tai WT, Cheng AL, Shiau CW, Liu CY, Ko CH, Lin MW, Chen PJ, Chen KF.
    Mol Cancer Ther; 2012 Feb 23; 11(2):452-63. PubMed ID: 22180308
    [Abstract] [Full Text] [Related]

  • 13. Polo-like kinase 2 is a mediator of hedgehog survival signaling in cholangiocarcinoma.
    Fingas CD, Mertens JC, Razumilava N, Sydor S, Bronk SF, Christensen JD, Ilyas SI, Canbay A, Treckmann JW, Paul A, Sirica AE, Gores GJ.
    Hepatology; 2013 Oct 23; 58(4):1362-74. PubMed ID: 23703673
    [Abstract] [Full Text] [Related]

  • 14. A smac mimetic reduces TNF related apoptosis inducing ligand (TRAIL)-induced invasion and metastasis of cholangiocarcinoma cells.
    Fingas CD, Blechacz BR, Smoot RL, Guicciardi ME, Mott J, Bronk SF, Werneburg NW, Sirica AE, Gores GJ.
    Hepatology; 2010 Aug 23; 52(2):550-61. PubMed ID: 20683954
    [Abstract] [Full Text] [Related]

  • 15. Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways.
    Prakobwong S, Gupta SC, Kim JH, Sung B, Pinlaor P, Hiraku Y, Wongkham S, Sripa B, Pinlaor S, Aggarwal BB.
    Carcinogenesis; 2011 Sep 23; 32(9):1372-80. PubMed ID: 21325634
    [Abstract] [Full Text] [Related]

  • 16. Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells.
    Ding X, Chaiteerakij R, Moser CD, Shaleh H, Boakye J, Chen G, Ndzengue A, Li Y, Zhou Y, Huang S, Sinicrope FA, Zou X, Thomas MB, Smith CD, Roberts LR.
    Oncotarget; 2016 Apr 12; 7(15):20080-92. PubMed ID: 26956050
    [Abstract] [Full Text] [Related]

  • 17. Allicin Inhibits Proliferation and Invasion in Vitro and in Vivo via SHP-1-Mediated STAT3 Signaling in Cholangiocarcinoma.
    Chen H, Zhu B, Zhao L, Liu Y, Zhao F, Feng J, Jin Y, Sun J, Geng R, Wei Y.
    Cell Physiol Biochem; 2018 Apr 12; 47(2):641-653. PubMed ID: 29794468
    [Abstract] [Full Text] [Related]

  • 18. Induction of phosphatase shatterproof 2 by evodiamine suppresses the proliferation and invasion of human cholangiocarcinoma.
    Zhu B, Zhao L, Liu Y, Jin Y, Feng J, Zhao F, Sun J, Geng R, Wei Y.
    Int J Biochem Cell Biol; 2019 Mar 12; 108():98-110. PubMed ID: 30682488
    [Abstract] [Full Text] [Related]

  • 19. Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner.
    Kiprianova I, Remy J, Milosch N, Mohrenz IV, Seifert V, Aigner A, Kögel D.
    Neoplasia; 2015 Jul 12; 17(7):564-73. PubMed ID: 26297434
    [Abstract] [Full Text] [Related]

  • 20. Survival pathway of cholangiocarcinoma via AKT/mTOR signaling to escape RAF/MEK/ERK pathway inhibition by sorafenib.
    Yokoi K, Kobayashi A, Motoyama H, Kitazawa M, Shimizu A, Notake T, Yokoyama T, Matsumura T, Takeoka M, Miyagawa SI.
    Oncol Rep; 2018 Feb 12; 39(2):843-850. PubMed ID: 29251327
    [Abstract] [Full Text] [Related]

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