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112 related items for PubMed ID: 19826195

  • 1. High anti tumor activity against rhabdomyosarcoma cells and low normal cells cytotoxicity of heat shock protein 90 inhibitors, with special emphasis on 17-[2-(pyrrolidin-1-yl)ethyl]-aminno-17-demethoxygeldanamycin.
    Lukasiewicz E, Miekus K, Kijowski J, Gozdzik J, Wilusz M, Bobis-Wozowicz S, Wiecha O, Majka M.
    J Physiol Pharmacol; 2009 Sep; 60(3):161-6. PubMed ID: 19826195
    [Abstract] [Full Text] [Related]

  • 2. HSP90 antagonist, geldanamycin, inhibits proliferation, induces apoptosis and blocks migration of rhabdomyosarcoma cells in vitro and seeding into bone marrow in vivo.
    Lesko E, Gozdzik J, Kijowski J, Jenner B, Wiecha O, Majka M.
    Anticancer Drugs; 2007 Nov; 18(10):1173-81. PubMed ID: 17893518
    [Abstract] [Full Text] [Related]

  • 3. The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulation.
    Jeon YK, Park CH, Kim KY, Li YC, Kim J, Kim YA, Paik JH, Park BK, Kim CW, Kim YN.
    J Pathol; 2007 Oct; 213(2):170-9. PubMed ID: 17768706
    [Abstract] [Full Text] [Related]

  • 4. 17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.
    Miekus K, Kijowski J, Sekuła M, Majka M.
    Oncol Rep; 2012 Nov; 28(5):1903-9. PubMed ID: 22941268
    [Abstract] [Full Text] [Related]

  • 5. Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
    Schwock J, Pham NA, Cao MP, Hedley DW.
    Cancer Chemother Pharmacol; 2008 Apr; 61(4):669-81. PubMed ID: 17579866
    [Abstract] [Full Text] [Related]

  • 6. The geldanamycin analogue 17-allylamino-17-demethoxygeldanamycin inhibits the growth of GL261 glioma cells in vitro and in vivo.
    Newcomb EW, Lukyanov Y, Schnee T, Esencay M, Fischer I, Hong D, Shao Y, Zagzag D.
    Anticancer Drugs; 2007 Sep; 18(8):875-82. PubMed ID: 17667592
    [Abstract] [Full Text] [Related]

  • 7. Geldanamycin and its analog induce cytotoxicity in cultured human retinal pigment epithelial cells.
    Wu WC, Wu MH, Chang YC, Hsieh MC, Wu HJ, Cheng KC, Lai YH, Kao YH.
    Exp Eye Res; 2010 Aug; 91(2):211-9. PubMed ID: 20493187
    [Abstract] [Full Text] [Related]

  • 8. The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level.
    Yu W, Rao Q, Wang M, Tian Z, Lin D, Liu X, Wang J.
    Leuk Res; 2006 May; 30(5):575-82. PubMed ID: 16213582
    [Abstract] [Full Text] [Related]

  • 9. [Study on signal transduction pathway in differentiation and apoptosis of leukemia cells induced by heat shock protein inhibitor].
    Yu WJ, Rao Q, Wang M, Tian Z, Xu ZF, Wang JX.
    Zhonghua Xue Ye Xue Za Zhi; 2007 Oct; 28(10):677-80. PubMed ID: 18399173
    [Abstract] [Full Text] [Related]

  • 10. [The heat shock protein 90 inhibitor induces apoptosis and differentiation of Kasumi-1 and its mechanisms].
    Yu WJ, Rao Q, Wang M, Tian Z, Liu XR, Lin D, Wang JX.
    Zhonghua Xue Ye Xue Za Zhi; 2005 Dec; 26(12):728-31. PubMed ID: 16620576
    [Abstract] [Full Text] [Related]

  • 11. Heat shock protein 90 inhibitor induces apoptosis and attenuates activation of hepatic stellate cells.
    Myung SJ, Yoon JH, Kim BH, Lee JH, Jung EU, Lee HS.
    J Pharmacol Exp Ther; 2009 Jul; 330(1):276-82. PubMed ID: 19329756
    [Abstract] [Full Text] [Related]

  • 12. Anti-proliferative activity of heat shock protein (Hsp) 90 inhibitors via beta-catenin/TCF7L2 pathway in adult T cell leukemia cells.
    Kurashina R, Ohyashiki JH, Kobayashi C, Hamamura R, Zhang Y, Hirano T, Ohyashiki K.
    Cancer Lett; 2009 Oct 18; 284(1):62-70. PubMed ID: 19464103
    [Abstract] [Full Text] [Related]

  • 13. Protection of murine neural progenitor cells by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin in the low nanomolar concentration range.
    Wang G, Krishnamurthy K, Tangpisuthipongsa D.
    J Neurochem; 2011 May 18; 117(4):703-11. PubMed ID: 21395580
    [Abstract] [Full Text] [Related]

  • 14. Proteome-wide changes induced by the Hsp90 inhibitor, geldanamycin in anaplastic large cell lymphoma cells.
    Schumacher JA, Crockett DK, Elenitoba-Johnson KS, Lim MS.
    Proteomics; 2007 Aug 18; 7(15):2603-16. PubMed ID: 17610208
    [Abstract] [Full Text] [Related]

  • 15. Rituximab and 17-allylamino-17-demethoxygeldanamycin induce synergistic apoptosis in B-cell chronic lymphocytic leukaemia.
    Johnson AJ, Wagner AJ, Cheney CM, Smith LL, Lucas DM, Guster SK, Grever MR, Lin TS, Byrd JC.
    Br J Haematol; 2007 Dec 18; 139(5):837-44. PubMed ID: 17949452
    [Abstract] [Full Text] [Related]

  • 16. Resistance to geldanamycin-induced apoptosis in differentiated neuroblastoma SH-SY5Y cells.
    Shen JH, Zhang Y, Wu NH, Shen YF.
    Neurosci Lett; 2007 Mar 06; 414(2):110-4. PubMed ID: 17293044
    [Abstract] [Full Text] [Related]

  • 17. Hormone-refractory breast cancer remains sensitive to the antitumor activity of heat shock protein 90 inhibitors.
    Beliakoff J, Bagatell R, Paine-Murrieta G, Taylor CW, Lykkesfeldt AE, Whitesell L.
    Clin Cancer Res; 2003 Oct 15; 9(13):4961-71. PubMed ID: 14581371
    [Abstract] [Full Text] [Related]

  • 18. HSP90 inhibitor 17AAG causes apoptosis in ATRA-resistant acute promyelocytic leukemia cells.
    Meyer PN, Roychowdhury S, Kini AR, Alkan S.
    Leuk Res; 2008 Jan 15; 32(1):143-9. PubMed ID: 17617451
    [Abstract] [Full Text] [Related]

  • 19. p53 independent radio-sensitization of human lymphoblastoid cell lines by Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin.
    Fujii Y, Kato T, Kubota N, Fujimori A, Niwa O, Okayasu R.
    Oncol Rep; 2010 Jan 15; 23(1):199-203. PubMed ID: 19956882
    [Abstract] [Full Text] [Related]

  • 20. Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways.
    Gazitt Y, Kolaparthi V, Moncada K, Thomas C, Freeman J.
    Int J Oncol; 2009 Feb 15; 34(2):551-61. PubMed ID: 19148492
    [Abstract] [Full Text] [Related]

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