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Journal Abstract Search
260 related items for PubMed ID: 19836232
1. Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors. Jessop TC, Tarver JE, Carlsen M, Xu A, Healy JP, Heim-Riether A, Fu Q, Taylor JA, Augeri DJ, Shen M, Stouch TR, Swanson RV, Tari LW, Hunter M, Hoffman I, Keyes PE, Yu XC, Miranda M, Liu Q, Swaffield JC, David Kimball S, Nouraldeen A, Wilson AG, Foushee AM, Jhaver K, Finch R, Anderson S, Oravecz T, Carson KG. Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6784-7. PubMed ID: 19836232 [Abstract] [Full Text] [Related]
3. Design and synthesis of orally bioavailable benzimidazoles as Raf kinase inhibitors. Ramurthy S, Subramanian S, Aikawa M, Amiri P, Costales A, Dove J, Fong S, Jansen JM, Levine B, Ma S, McBride CM, Michaelian J, Pick T, Poon DJ, Girish S, Shafer CM, Stuart D, Sung L, Renhowe PA. J Med Chem; 2008 Nov 27; 51(22):7049-52. PubMed ID: 18942827 [Abstract] [Full Text] [Related]
8. Novel series of pyrrolotriazine analogs as highly potent pan-Aurora kinase inhibitors. Abraham S, Hadd MJ, Tran L, Vickers T, Sindac J, Milanov ZV, Holladay MW, Bhagwat SS, Hua H, Ford Pulido JM, Cramer MD, Gitnick D, James J, Dao A, Belli B, Armstrong RC, Treiber DK, Liu G. Bioorg Med Chem Lett; 2011 Sep 15; 21(18):5296-300. PubMed ID: 21802948 [Abstract] [Full Text] [Related]
9. Novel thienopyrimidine and thiazolopyrimidine kinase inhibitors with activity against Tie-2 in vitro and in vivo. Luke RW, Ballard P, Buttar D, Campbell L, Curwen J, Emery SC, Griffen AM, Hassall L, Hayter BR, Jones CD, McCoull W, Mellor M, Swain ML, Tucker JA. Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6670-4. PubMed ID: 19854647 [Abstract] [Full Text] [Related]
14. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation. Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, DiPietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Martin MW, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Wang L, White RD, Whittington DA, Zanon R. J Med Chem; 2008 Mar 27; 51(6):1649-67. PubMed ID: 18324761 [Abstract] [Full Text] [Related]
15. Design and synthesis of Rho kinase inhibitors (II). Iwakubo M, Takami A, Okada Y, Kawata T, Tagami Y, Ohashi H, Sato M, Sugiyama T, Fukushima K, Iijima H. Bioorg Med Chem; 2007 Jan 01; 15(1):350-64. PubMed ID: 17046269 [Abstract] [Full Text] [Related]
16. N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: a novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors. Mannion M, Raeppel S, Claridge S, Zhou N, Saavedra O, Isakovic L, Zhan L, Gaudette F, Raeppel F, Déziel R, Beaulieu N, Nguyen H, Chute I, Beaulieu C, Dupont I, Robert MF, Lefebvre S, Dubay M, Rahil J, Wang J, Ste-Croix H, Robert Macleod A, Besterman JM, Vaisburg A. Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6552-6. PubMed ID: 19854051 [Abstract] [Full Text] [Related]
17. 2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2. Ledeboer MW, Pierce AC, Duffy JP, Gao H, Messersmith D, Salituro FG, Nanthakumar S, Come J, Zuccola HJ, Swenson L, Shlyakter D, Mahajan S, Hoock T, Fan B, Tsai WJ, Kolaczkowski E, Carrier S, Hogan JK, Zessis R, Pazhanisamy S, Bennani YL. Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6529-33. PubMed ID: 19857967 [Abstract] [Full Text] [Related]
18. Discovery of pyrimidine benzimidazoles as Src-family selective Lck inhibitors. Part II. Zhang G, Ren P, Gray NS, Sim T, Wang X, Liu Y, Che J, Dong W, Tian SS, Sandberg ML, Spalding TA, Romeo R, Iskandar M, Wang Z, Seidel HM, Karanewsky DS, He Y. Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6691-5. PubMed ID: 19854052 [Abstract] [Full Text] [Related]