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Journal Abstract Search

188 related items for PubMed ID: 19838062

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  • 3. Daucosterol disturbs redox homeostasis and elicits oxidative-stress mediated apoptosis in A549 cells via targeting thioredoxin reductase by a p53 dependent mechanism.
    Rajavel T, Banu Priya G, Suryanarayanan V, Singh SK, Pandima Devi K.
    Eur J Pharmacol; 2019 Jul 15; 855():112-123. PubMed ID: 31059712
    [Abstract] [Full Text] [Related]

  • 4. Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.
    Sachweh MC, Stafford WC, Drummond CJ, McCarthy AR, Higgins M, Campbell J, Brodin B, Arnér ES, Laín S.
    Oncotarget; 2015 Jun 30; 6(18):16488-506. PubMed ID: 26029997
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  • 5. APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase.
    Peng X, Zhang MQ, Conserva F, Hosny G, Selivanova G, Bykov VJ, Arnér ES, Wiman KG.
    Cell Death Dis; 2013 Oct 24; 4(10):e881. PubMed ID: 24157875
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  • 6. Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation.
    Chen W, Zou P, Zhao Z, Weng Q, Chen X, Ying S, Ye Q, Wang Z, Ji J, Liang G.
    Oncotarget; 2016 Mar 29; 7(13):16593-609. PubMed ID: 26919094
    [Abstract] [Full Text] [Related]

  • 7. The conserved Trp114 residue of thioredoxin reductase 1 has a redox sensor-like function triggering oligomerization and crosslinking upon oxidative stress related to cell death.
    Xu J, Eriksson SE, Cebula M, Sandalova T, Hedström E, Pader I, Cheng Q, Myers CR, Antholine WE, Nagy P, Hellman U, Selivanova G, Lindqvist Y, Arnér ES.
    Cell Death Dis; 2015 Jan 22; 6(1):e1616. PubMed ID: 25611390
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  • 8. Inducing ubiquitination and degradation of TrxR1 protein by LW-216 promotes apoptosis in non-small cell lung cancer via triggering ROS production.
    Wang R, Zhong L, Wang T, Sun T, Yang J, Liu X, Wu Y, Guo Q, Gao Y, Zhao K.
    Neoplasia; 2024 Jul 22; 53():101004. PubMed ID: 38733769
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  • 9. High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy.
    Eriksson SE, Prast-Nielsen S, Flaberg E, Szekely L, Arnér ES.
    Free Radic Biol Med; 2009 Dec 01; 47(11):1661-71. PubMed ID: 19766715
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  • 10. Dual inhibition of thioredoxin reductase and proteasome is required for auranofin-induced paraptosis in breast cancer cells.
    Seo MJ, Kim IY, Lee DM, Park YJ, Cho MY, Jin HJ, Choi KS.
    Cell Death Dis; 2023 Jan 19; 14(1):42. PubMed ID: 36658130
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  • 11. Ethaselen: a potent mammalian thioredoxin reductase 1 inhibitor and novel organoselenium anticancer agent.
    Wang L, Yang Z, Fu J, Yin H, Xiong K, Tan Q, Jin H, Li J, Wang T, Tang W, Yin J, Cai G, Liu M, Kehr S, Becker K, Zeng H.
    Free Radic Biol Med; 2012 Mar 01; 52(5):898-908. PubMed ID: 22210352
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  • 12. EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells.
    Zou P, Xia Y, Chen W, Chen X, Ying S, Feng Z, Chen T, Ye Q, Wang Z, Qiu C, Yang S, Liang G.
    Oncotarget; 2016 Apr 05; 7(14):18050-64. PubMed ID: 26919110
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of thioredoxin reductase 1 by caveolin 1 promotes stress-induced premature senescence.
    Volonte D, Galbiati F.
    EMBO Rep; 2009 Dec 05; 10(12):1334-40. PubMed ID: 19820694
    [Abstract] [Full Text] [Related]

  • 14. Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer.
    Oh BM, Lee SJ, Cho HJ, Park YS, Kim JT, Yoon SR, Lee SC, Lim JS, Kim BY, Choe YK, Lee HG.
    Cell Death Dis; 2017 Mar 16; 8(3):e2682. PubMed ID: 28300829
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  • 15. Oxidation of structural cysteine residues in thioredoxin 1 by aromatic arsenicals enhances cancer cell cytotoxicity caused by the inhibition of thioredoxin reductase 1.
    Zhang X, Lu J, Ren X, Du Y, Zheng Y, Ioannou PV, Holmgren A.
    Free Radic Biol Med; 2015 Dec 16; 89():192-200. PubMed ID: 26169724
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  • 16. Chk2 mediates RITA-induced apoptosis.
    de Lange J, Verlaan-de Vries M, Teunisse AF, Jochemsen AG.
    Cell Death Differ; 2012 Jun 16; 19(6):980-9. PubMed ID: 22158418
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  • 17. Combination of TrxR1 inhibitor and lenvatinib triggers ROS-dependent cell death in human lung cancer cells.
    Zheng P, Xia Y, Shen X, Lu H, Chen Y, Xu C, Qiu C, Zhang Y, Zou P, Cui R, Huang X.
    Int J Biol Sci; 2024 Jun 16; 20(1):249-264. PubMed ID: 38164168
    [Abstract] [Full Text] [Related]

  • 18. Curcuminoid B63 induces ROS-mediated paraptosis-like cell death by targeting TrxR1 in gastric cells.
    Chen X, Chen X, Zhang X, Wang L, Cao P, Rajamanickam V, Wu C, Zhou H, Cai Y, Liang G, Wang Y.
    Redox Biol; 2019 Feb 16; 21():101061. PubMed ID: 30590310
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  • 19. Zebularine inhibits the growth of A549 lung cancer cells via cell cycle arrest and apoptosis.
    You BR, Park WH.
    Mol Carcinog; 2014 Nov 16; 53(11):847-57. PubMed ID: 23661569
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  • 20. Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer.
    Zhuge W, Chen R, Vladimir K, Dong X, Zia K, Sun X, Dai X, Bao M, Shen X, Liang G.
    Cancer Lett; 2018 Jan 01; 412():46-58. PubMed ID: 29037867
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