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135 related items for PubMed ID: 19845616

  • 1. Oxidative DNA modifications in hypoxic signaling.
    Gillespie MN, Pastukh V, Ruchko MV.
    Ann N Y Acad Sci; 2009 Oct; 1177():140-50. PubMed ID: 19845616
    [Abstract] [Full Text] [Related]

  • 2. Controlled DNA "damage" and repair in hypoxic signaling.
    Gillespie MN, Pastukh VM, Ruchko MV.
    Respir Physiol Neurobiol; 2010 Dec 31; 174(3):244-51. PubMed ID: 20831905
    [Abstract] [Full Text] [Related]

  • 3. An oxidative DNA "damage" and repair mechanism localized in the VEGF promoter is important for hypoxia-induced VEGF mRNA expression.
    Pastukh V, Roberts JT, Clark DW, Bardwell GC, Patel M, Al-Mehdi AB, Borchert GM, Gillespie MN.
    Am J Physiol Lung Cell Mol Physiol; 2015 Dec 01; 309(11):L1367-75. PubMed ID: 26432868
    [Abstract] [Full Text] [Related]

  • 4. Oxidants in signal transduction: impact on DNA integrity and gene expression.
    Ziel KA, Grishko V, Campbell CC, Breit JF, Wilson GL, Gillespie MN.
    FASEB J; 2005 Mar 01; 19(3):387-94. PubMed ID: 15746182
    [Abstract] [Full Text] [Related]

  • 5. Sequence-specific oxidative base modifications in hypoxia-inducible genes.
    Pastukh V, Ruchko M, Gorodnya O, Wilson GL, Gillespie MN.
    Free Radic Biol Med; 2007 Dec 15; 43(12):1616-26. PubMed ID: 18037127
    [Abstract] [Full Text] [Related]

  • 6. Hypoxia-induced oxidative base modifications in the VEGF hypoxia-response element are associated with transcriptionally active nucleosomes.
    Ruchko MV, Gorodnya OM, Pastukh VM, Swiger BM, Middleton NS, Wilson GL, Gillespie MN.
    Free Radic Biol Med; 2009 Feb 01; 46(3):352-9. PubMed ID: 18992807
    [Abstract] [Full Text] [Related]

  • 7. Nuclear protein-induced bending and flexing of the hypoxic response element of the rat vascular endothelial growth factor promoter.
    Breit JF, Ault-Ziel K, Al-Mehdi AB, Gillespie MN.
    FASEB J; 2008 Jan 01; 22(1):19-29. PubMed ID: 17766324
    [Abstract] [Full Text] [Related]

  • 8. Ref-1/Ape is critical for formation of the hypoxia-inducible transcriptional complex on the hypoxic response element of the rat pulmonary artery endothelial cell VEGF gene.
    Ziel KA, Campbell CC, Wilson GL, Gillespie MN.
    FASEB J; 2004 Jun 01; 18(9):986-8. PubMed ID: 15084519
    [Abstract] [Full Text] [Related]

  • 9. Promoter G-quadruplex sequences are targets for base oxidation and strand cleavage during hypoxia-induced transcription.
    Clark DW, Phang T, Edwards MG, Geraci MW, Gillespie MN.
    Free Radic Biol Med; 2012 Jul 01; 53(1):51-9. PubMed ID: 22583700
    [Abstract] [Full Text] [Related]

  • 10. Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription.
    Al-Mehdi AB, Pastukh VM, Swiger BM, Reed DJ, Patel MR, Bardwell GC, Pastukh VV, Alexeyev MF, Gillespie MN.
    Sci Signal; 2012 Jul 03; 5(231):ra47. PubMed ID: 22763339
    [Abstract] [Full Text] [Related]

  • 11. Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair.
    Fleming AM, Ding Y, Burrows CJ.
    Proc Natl Acad Sci U S A; 2017 Mar 07; 114(10):2604-2609. PubMed ID: 28143930
    [Abstract] [Full Text] [Related]

  • 12. Hypoxia promotes oxidative base modifications in the pulmonary artery endothelial cell VEGF gene.
    Grishko V, Solomon M, Breit JF, Killilea DW, Ledoux SP, Wilson GL, Gillespie MN.
    FASEB J; 2001 May 07; 15(7):1267-9. PubMed ID: 11344109
    [No Abstract] [Full Text] [Related]

  • 13. Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3'-kinase and distinct from that induced by hypoxia.
    Maity A, Pore N, Lee J, Solomon D, O'Rourke DM.
    Cancer Res; 2000 Oct 15; 60(20):5879-86. PubMed ID: 11059786
    [Abstract] [Full Text] [Related]

  • 14. Hypoxia-induced transcriptional activation of vascular endothelial growth factor is inhibited by serum.
    D'Angelo G, Ladoux A, Frelin C.
    Biochem Biophys Res Commun; 2000 Jan 07; 267(1):334-8. PubMed ID: 10623620
    [Abstract] [Full Text] [Related]

  • 15. Regulation of mitochondrial genome replication by hypoxia: The role of DNA oxidation in D-loop region.
    Pastukh VM, Gorodnya OM, Gillespie MN, Ruchko MV.
    Free Radic Biol Med; 2016 Jul 07; 96():78-88. PubMed ID: 27091693
    [Abstract] [Full Text] [Related]

  • 16. Distinct APE1 Activities Affect the Regulation of VEGF Transcription Under Hypoxic Conditions.
    Li M, Dai N, Wang D, Zhong Z.
    Comput Struct Biotechnol J; 2019 Jul 07; 17():324-332. PubMed ID: 30906512
    [Abstract] [Full Text] [Related]

  • 17. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1.
    Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, Semenza GL.
    Mol Cell Biol; 1996 Sep 07; 16(9):4604-13. PubMed ID: 8756616
    [Abstract] [Full Text] [Related]

  • 18. A potential role for reactive oxygen species and the HIF-1alpha-VEGF pathway in hypoxia-induced pulmonary vascular leak.
    Irwin DC, McCord JM, Nozik-Grayck E, Beckly G, Foreman B, Sullivan T, White M, T Crossno J, Bailey D, Flores SC, Majka S, Klemm D, van Patot MC.
    Free Radic Biol Med; 2009 Jul 01; 47(1):55-61. PubMed ID: 19358884
    [Abstract] [Full Text] [Related]

  • 19. Inhibitory mechanism of vascular endothelial growth factor (VEGF) by bucillamine.
    Koyama S, Takagi H, Otani A, Oh H, Nishimura K, Honda Y.
    Br J Pharmacol; 2002 Nov 01; 137(6):901-9. PubMed ID: 12411422
    [Abstract] [Full Text] [Related]

  • 20. Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide.
    Kimura H, Weisz A, Kurashima Y, Hashimoto K, Ogura T, D'Acquisto F, Addeo R, Makuuchi M, Esumi H.
    Blood; 2000 Jan 01; 95(1):189-97. PubMed ID: 10607702
    [Abstract] [Full Text] [Related]

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