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208 related items for PubMed ID: 19850059

  • 1. Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1.
    Ilic Z, Crawford D, Vakharia D, Egner PA, Sell S.
    Toxicol Appl Pharmacol; 2010 Feb 01; 242(3):241-6. PubMed ID: 19850059
    [Abstract] [Full Text] [Related]

  • 2. Expression of stably transfected murine glutathione S-transferase A3-3 protects against nucleic acid alkylation and cytotoxicity by aflatoxin B1 in hamster V79 cells expressing rat cytochrome P450-2B1.
    Fields WR, Morrow CS, Doehmer J, Townsend AJ.
    Carcinogenesis; 1999 Jun 01; 20(6):1121-5. PubMed ID: 10357798
    [Abstract] [Full Text] [Related]

  • 3. Characterization of liver injury, oval cell proliferation and cholangiocarcinogenesis in glutathione S-transferase A3 knockout mice.
    Crawford DR, Ilic Z, Guest I, Milne GL, Hayes JD, Sell S.
    Carcinogenesis; 2017 Jul 01; 38(7):717-727. PubMed ID: 28535182
    [Abstract] [Full Text] [Related]

  • 4. Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element.
    Jowsey IR, Jiang Q, Itoh K, Yamamoto M, Hayes JD.
    Mol Pharmacol; 2003 Nov 01; 64(5):1018-28. PubMed ID: 14573750
    [Abstract] [Full Text] [Related]

  • 5. Low hepatic glutathione S-transferase and increased hepatic DNA adduction contribute to increased tumorigenicity of aflatoxin B1 in newborn and partially hepatectomized mice.
    Shupe T, Sell S.
    Toxicol Lett; 2004 Mar 14; 148(1-2):1-9. PubMed ID: 15019083
    [Abstract] [Full Text] [Related]

  • 6. Participation of liver stem cells in cholangiocarcinogenesis after aflatoxin B1 exposure of glutathione S-transferase A3 knockout mice.
    Ilic Z, Mondal TK, Guest I, Crawford DR, Sell S.
    Tumour Biol; 2018 May 14; 40(5):1010428318777344. PubMed ID: 29804515
    [Abstract] [Full Text] [Related]

  • 7. Food restriction reduces aflatoxin B1 (AFB1)-DNA adduct formation, AFB1-glutathione conjugation, and DNA damage in AFB1-treated male F344 rats and B6C3F1 mice.
    Chou MW, Chen W.
    J Nutr; 1997 Feb 14; 127(2):210-7. PubMed ID: 9039820
    [Abstract] [Full Text] [Related]

  • 8. Changes in hepatic cytosolic glutathione S-transferase activity and expression of its class-P during prenatal and postnatal period in rats treated with aflatoxin B1.
    Fatemi F, Allameh A, Dadkhah A, Forouzandeh M, Kazemnejad S, Sharifi R.
    Arch Toxicol; 2006 Sep 14; 80(9):572-9. PubMed ID: 16501953
    [Abstract] [Full Text] [Related]

  • 9. Genetic or pharmacologic activation of Nrf2 signaling fails to protect against aflatoxin genotoxicity in hypersensitive GSTA3 knockout mice.
    Kensler KH, Slocum SL, Chartoumpekis DV, Dolan PM, Johnson NM, Ilic Z, Crawford DR, Sell S, Groopman JD, Kensler TW, Egner PA.
    Toxicol Sci; 2014 Jun 14; 139(2):293-300. PubMed ID: 24675090
    [Abstract] [Full Text] [Related]

  • 10. Low-dose microcystin-LR antagonizes aflatoxin B1 induced hepatocarcinogenesis through decreasing cytochrome P450 1A2 expression and aflatoxin B1-DNA adduct generation.
    Wang L, He L, Zeng H, Fu W, Wang J, Tan Y, Zheng C, Qiu Z, Luo J, Lv C, Huang Y, Shu W.
    Chemosphere; 2020 Jun 14; 248():126036. PubMed ID: 32045972
    [Abstract] [Full Text] [Related]

  • 11. The Effects of Curcumin on Aflatoxin B1- Induced Toxicity in Rats.
    Poapolathep S, Imsilp K, Machii K, Kumagai S, Poapolathep A.
    Biocontrol Sci; 2015 Jun 14; 20(3):171-7. PubMed ID: 26412696
    [Abstract] [Full Text] [Related]

  • 12. Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma.
    Chawanthayatham S, Valentine CC, Fedeles BI, Fox EJ, Loeb LA, Levine SS, Slocum SL, Wogan GN, Croy RG, Essigmann JM.
    Proc Natl Acad Sci U S A; 2017 Apr 11; 114(15):E3101-E3109. PubMed ID: 28351974
    [Abstract] [Full Text] [Related]

  • 13. Resistance to aflatoxin B1 is associated with the expression of a novel aldo-keto reductase which has catalytic activity towards a cytotoxic aldehyde-containing metabolite of the toxin.
    Hayes JD, Judah DJ, Neal GE.
    Cancer Res; 1993 Sep 01; 53(17):3887-94. PubMed ID: 8395332
    [Abstract] [Full Text] [Related]

  • 14. Temporal patterns of DNA adduct formation and glutathione S-transferase activity in the testes of rats fed aflatoxin B1: a comparison with patterns in the liver.
    Sotomayor RE, Sahu S, Washington M, Hinton DM, Chou M.
    Environ Mol Mutagen; 1999 Sep 01; 33(4):293-302. PubMed ID: 10398377
    [Abstract] [Full Text] [Related]

  • 15. Complete protection against aflatoxin B(1)-induced liver cancer with a triterpenoid: DNA adduct dosimetry, molecular signature, and genotoxicity threshold.
    Johnson NM, Egner PA, Baxter VK, Sporn MB, Wible RS, Sutter TR, Groopman JD, Kensler TW, Roebuck BD.
    Cancer Prev Res (Phila); 2014 Jul 01; 7(7):658-65. PubMed ID: 24662598
    [Abstract] [Full Text] [Related]

  • 16. Associations of plasma aflatoxin B1-albumin adduct level with plasma selenium level and genetic polymorphisms of glutathione S-transferase M1 and T1.
    Chen SY, Chen CJ, Tsai WY, Ahsan H, Liu TY, Lin JT, Santella RM.
    Nutr Cancer; 2000 Jul 01; 38(2):179-85. PubMed ID: 11525595
    [Abstract] [Full Text] [Related]

  • 17. Development of an adverse outcome pathway for chemically induced hepatocellular carcinoma: case study of AFB1, a human carcinogen with a mutagenic mode of action.
    Moore MM, Schoeny RS, Becker RA, White K, Pottenger LH.
    Crit Rev Toxicol; 2018 Apr 01; 48(4):312-337. PubMed ID: 29431554
    [Abstract] [Full Text] [Related]

  • 18. Identification of differentially expressed genes in aflatoxin B1-treated cultured primary rat hepatocytes and Fischer 344 rats.
    Harris AJ, Shaddock JG, Manjanatha MG, Lisenbey JA, Casciano DA.
    Carcinogenesis; 1998 Aug 01; 19(8):1451-8. PubMed ID: 9744542
    [Abstract] [Full Text] [Related]

  • 19. Mutations in the p53 tumor suppressor gene in tree shrew hepatocellular carcinoma associated with hepatitis B virus infection and intake of aflatoxin B1.
    Park US, Su JJ, Ban KC, Qin L, Lee EH, Lee YI.
    Gene; 2000 Jun 13; 251(1):73-80. PubMed ID: 10863098
    [Abstract] [Full Text] [Related]

  • 20. Interaction of DNA repair gene polymorphisms and aflatoxin B1 in the risk of hepatocellular carcinoma.
    Yao JG, Huang XY, Long XD.
    Int J Clin Exp Pathol; 2014 Jun 13; 7(9):6231-44. PubMed ID: 25337275
    [Abstract] [Full Text] [Related]

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