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PUBMED FOR HANDHELDS

Journal Abstract Search

260 related items for PubMed ID: 19850474

  • 1. Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.
    Vincent F, Nguyen MT, Emerling DE, Kelly MG, Duncton MA.
    Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6793-6. PubMed ID: 19850474
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands.
    Morera E, De Petrocellis L, Morera L, Moriello AS, Ligresti A, Nalli M, Woodward DF, Di Marzo V, Ortar G.
    Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6806-9. PubMed ID: 19875281
    [Abstract] [Full Text] [Related]

  • 3. Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).
    Korhonen J, Kuusisto A, van Bruchem J, Patel JZ, Laitinen T, Navia-Paldanius D, Laitinen JT, Savinainen JR, Parkkari T, Nevalainen TJ.
    Bioorg Med Chem; 2014 Dec 01; 22(23):6694-6705. PubMed ID: 25282655
    [Abstract] [Full Text] [Related]

  • 4. 3-Heterocycle-phenyl N-alkylcarbamates as FAAH inhibitors: design, synthesis and 3D-QSAR studies.
    Käsnänen H, Myllymäki MJ, Minkkilä A, Kataja AO, Saario SM, Nevalainen T, Koskinen AM, Poso A.
    ChemMedChem; 2010 Feb 01; 5(2):213-31. PubMed ID: 20024981
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis, and in vitro evaluation of carbamate derivatives of 2-benzoxazolyl- and 2-benzothiazolyl-(3-hydroxyphenyl)-methanones as novel fatty acid amide hydrolase inhibitors.
    Myllymäki MJ, Saario SM, Kataja AO, Castillo-Melendez JA, Nevalainen T, Juvonen RO, Järvinen T, Koskinen AM.
    J Med Chem; 2007 Aug 23; 50(17):4236-42. PubMed ID: 17665899
    [Abstract] [Full Text] [Related]

  • 6. Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets.
    Zhang D, Saraf A, Kolasa T, Bhatia P, Zheng GZ, Patel M, Lannoye GS, Richardson P, Stewart A, Rogers JC, Brioni JD, Surowy CS.
    Neuropharmacology; 2007 Mar 23; 52(4):1095-105. PubMed ID: 17217969
    [Abstract] [Full Text] [Related]

  • 7. A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.
    Gattinoni S, Simone CD, Dallavalle S, Fezza F, Nannei R, Battista N, Minetti P, Quattrociocchi G, Caprioli A, Borsini F, Cabri W, Penco S, Merlini L, Maccarrone M.
    Bioorg Med Chem Lett; 2010 Aug 01; 20(15):4406-11. PubMed ID: 20591666
    [Abstract] [Full Text] [Related]

  • 8. Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies.
    Mor M, Rivara S, Lodola A, Plazzi PV, Tarzia G, Duranti A, Tontini A, Piersanti G, Kathuria S, Piomelli D.
    J Med Chem; 2004 Oct 07; 47(21):4998-5008. PubMed ID: 15456244
    [Abstract] [Full Text] [Related]

  • 9. Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold.
    Morera L, Labar G, Ortar G, Lambert DM.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6260-75. PubMed ID: 23036333
    [Abstract] [Full Text] [Related]

  • 10. Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase.
    Minkkilä A, Saario SM, Käsnänen H, Leppänen J, Poso A, Nevalainen T.
    J Med Chem; 2008 Nov 27; 51(22):7057-60. PubMed ID: 18983140
    [Abstract] [Full Text] [Related]

  • 11. Design of on-target FAAH inhibitors.
    Deutsch DG.
    Chem Biol; 2005 Nov 27; 12(11):1157-8. PubMed ID: 16298293
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and structure-activity relationships of FAAH inhibitors: cyclohexylcarbamic acid biphenyl esters with chemical modulation at the proximal phenyl ring.
    Tarzia G, Duranti A, Gatti G, Piersanti G, Tontini A, Rivara S, Lodola A, Plazzi PV, Mor M, Kathuria S, Piomelli D.
    ChemMedChem; 2006 Jan 27; 1(1):130-9. PubMed ID: 16892344
    [Abstract] [Full Text] [Related]

  • 13. Structure based design of novel irreversible FAAH inhibitors.
    Wang JL, Bowen SJ, Schweitzer BA, Madsen HM, McDonald J, Pelc MJ, Tenbrink RE, Beidler D, Thorarensen A.
    Bioorg Med Chem Lett; 2009 Oct 15; 19(20):5970-4. PubMed ID: 19765986
    [Abstract] [Full Text] [Related]

  • 14. Chiral 3-(4,5-dihydrooxazol-2-yl)phenyl alkylcarbamates as novel FAAH inhibitors: Insight into FAAH enantioselectivity by molecular docking and interaction fields.
    Myllymäki MJ, Käsnänen H, Kataja AO, Lahtela-Kakkonen M, Saario SM, Poso A, Koskinen AM.
    Eur J Med Chem; 2009 Oct 15; 44(10):4179-91. PubMed ID: 19539407
    [Abstract] [Full Text] [Related]

  • 15. 1-Indol-1-yl-propan-2-ones and related heterocyclic compounds as dual inhibitors of cytosolic phospholipase A(2)alpha and fatty acid amide hydrolase.
    Forster L, Ludwig J, Kaptur M, Bovens S, Elfringhoff AS, Holtfrerich A, Lehr M.
    Bioorg Med Chem; 2010 Jan 15; 18(2):945-52. PubMed ID: 20005725
    [Abstract] [Full Text] [Related]

  • 16. Understanding the role of carbamate reactivity in fatty acid amide hydrolase inhibition by QM/MM mechanistic modelling.
    Lodola A, Capoferri L, Rivara S, Chudyk E, Sirirak J, Dyguda-Kazimierowicz E, Andrzej Sokalski W, Mileni M, Tarzia G, Piomelli D, Mor M, Mulholland AJ.
    Chem Commun (Camb); 2011 Mar 07; 47(9):2517-9. PubMed ID: 21240393
    [Abstract] [Full Text] [Related]

  • 17. Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system.
    Gattinoni S, De Simone C, Dallavalle S, Fezza F, Nannei R, Amadio D, Minetti P, Quattrociocchi G, Caprioli A, Borsini F, Cabri W, Penco S, Merlini L, Maccarrone M.
    ChemMedChem; 2010 Mar 01; 5(3):357-60. PubMed ID: 20112328
    [No Abstract] [Full Text] [Related]

  • 18. Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamate FAAH inhibitors.
    Valitutti G, Duranti A, Lodola A, Mor M, Piersanti G, Piomelli D, Rivara S, Tontini A, Tarzia G, Traldi P.
    J Mass Spectrom; 2007 Dec 01; 42(12):1624-7. PubMed ID: 18085570
    [No Abstract] [Full Text] [Related]

  • 19. Tandem mass spectrometric data-FAAH inhibitory activity relationships of some carbamic acid O-aryl esters.
    Basso E, Duranti A, Mor M, Piomelli D, Tontini A, Tarzia G, Traldi P.
    J Mass Spectrom; 2004 Dec 01; 39(12):1450-5. PubMed ID: 15578755
    [Abstract] [Full Text] [Related]

  • 20. Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2,4-diones as fatty acid amide hydrolase inhibitors templates.
    Muccioli GG, Fazio N, Scriba GK, Poppitz W, Cannata F, Poupaert JH, Wouters J, Lambert DM.
    J Med Chem; 2006 Jan 12; 49(1):417-25. PubMed ID: 16392827
    [Abstract] [Full Text] [Related]

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