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Journal Abstract Search

440 related items for PubMed ID: 19850644

  • 1. Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.
    Ren H, Aleksunes LM, Wood C, Vallanat B, George MH, Klaassen CD, Corton JC.
    Toxicol Sci; 2010 Jan; 113(1):45-59. PubMed ID: 19850644
    [Abstract] [Full Text] [Related]

  • 2. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R, Benoki S, Numakura Y, Kodama S, Miyata M, Yamazoe Y, Yoshinari K.
    PLoS One; 2013 Jan; 8(4):e61802. PubMed ID: 23626729
    [Abstract] [Full Text] [Related]

  • 3. Di-(2-ethylhexyl)-phthalate (DEHP) activates the constitutive androstane receptor (CAR): a novel signalling pathway sensitive to phthalates.
    Eveillard A, Mselli-Lakhal L, Mogha A, Lasserre F, Polizzi A, Pascussi JM, Guillou H, Martin PG, Pineau T.
    Biochem Pharmacol; 2009 Jun 01; 77(11):1735-46. PubMed ID: 19428328
    [Abstract] [Full Text] [Related]

  • 4. Constitutive androstane receptor (CAR) mediates dieldrin-induced liver tumorigenesis in mouse.
    Wang Z, Wu Q, Li X, Klaunig JE.
    Arch Toxicol; 2020 Aug 01; 94(8):2873-2884. PubMed ID: 32435917
    [Abstract] [Full Text] [Related]

  • 5. PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling.
    Rosen MB, Das KP, Rooney J, Abbott B, Lau C, Corton JC.
    Toxicology; 2017 Jul 15; 387():95-107. PubMed ID: 28558994
    [Abstract] [Full Text] [Related]

  • 6. Hepatic peroxisome proliferator-activated receptor α may have an important role in the toxic effects of di(2-ethylhexyl)phthalate on offspring of mice.
    Hayashi Y, Ito Y, Yamagishi N, Yanagiba Y, Tamada H, Wang D, Ramdhan DH, Naito H, Harada Y, Kamijima M, Gonzales FJ, Nakajima T.
    Toxicology; 2011 Oct 28; 289(1):1-10. PubMed ID: 21354252
    [Abstract] [Full Text] [Related]

  • 7. Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR.
    Rosen MB, Lee JS, Ren H, Vallanat B, Liu J, Waalkes MP, Abbott BD, Lau C, Corton JC.
    Toxicol Sci; 2008 May 28; 103(1):46-56. PubMed ID: 18281256
    [Abstract] [Full Text] [Related]

  • 8. Peroxisome proliferator-activated receptor alpha protects against glomerulonephritis induced by long-term exposure to the plasticizer di-(2-ethylhexyl)phthalate.
    Kamijo Y, Hora K, Nakajima T, Kono K, Takahashi K, Ito Y, Higuchi M, Kiyosawa K, Shigematsu H, Gonzalez FJ, Aoyama T.
    J Am Soc Nephrol; 2007 Jan 28; 18(1):176-88. PubMed ID: 17135395
    [Abstract] [Full Text] [Related]

  • 9. Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.
    Guo D, Sarkar J, Suino-Powell K, Xu Y, Matsumoto K, Jia Y, Yu S, Khare S, Haldar K, Rao MS, Foreman JE, Monga SP, Peters JM, Xu HE, Reddy JK.
    J Biol Chem; 2007 Dec 14; 282(50):36766-76. PubMed ID: 17962186
    [Abstract] [Full Text] [Related]

  • 10. Different mechanisms of DEHP-induced hepatocellular adenoma tumorigenesis in wild-type and Ppar alpha-null mice.
    Takashima K, Ito Y, Gonzalez FJ, Nakajima T.
    J Occup Health; 2008 Dec 14; 50(2):169-80. PubMed ID: 18403868
    [Abstract] [Full Text] [Related]

  • 11. Mechanistic considerations for human relevance of cancer hazard of di(2-ethylhexyl) phthalate.
    Rusyn I, Corton JC.
    Mutat Res; 2012 Dec 14; 750(2):141-158. PubMed ID: 22198209
    [Abstract] [Full Text] [Related]

  • 12. Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome proliferator-activated receptor alpha: a review.
    Ito Y, Kamijima M, Nakajima T.
    Environ Health Prev Med; 2019 Jul 06; 24(1):47. PubMed ID: 31279339
    [Abstract] [Full Text] [Related]

  • 13. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
    Cheng X, Klaassen CD.
    Toxicol Sci; 2008 Nov 06; 106(1):29-36. PubMed ID: 18648086
    [Abstract] [Full Text] [Related]

  • 14. Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)?
    Melnick RL.
    Environ Health Perspect; 2001 May 06; 109(5):437-42. PubMed ID: 11401753
    [Abstract] [Full Text] [Related]

  • 15. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.
    Buckley DB, Klaassen CD.
    Drug Metab Dispos; 2009 Apr 06; 37(4):847-56. PubMed ID: 19144771
    [Abstract] [Full Text] [Related]

  • 16. A cancer risk assessment of di(2-ethylhexyl)phthalate: application of the new U.S. EPA Risk Assessment Guidelines.
    Doull J, Cattley R, Elcombe C, Lake BG, Swenberg J, Wilkinson C, Williams G, van Gemert M.
    Regul Toxicol Pharmacol; 1999 Jun 06; 29(3):327-57. PubMed ID: 10388618
    [Abstract] [Full Text] [Related]

  • 17. Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase.
    Woods CG, Burns AM, Maki A, Bradford BU, Cunningham ML, Connor HD, Kadiiska MB, Mason RP, Peters JM, Rusyn I.
    Free Radic Biol Med; 2007 Feb 01; 42(3):335-42. PubMed ID: 17210446
    [Abstract] [Full Text] [Related]

  • 18. Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice.
    Ward JM, Peters JM, Perella CM, Gonzalez FJ.
    Toxicol Pathol; 1998 Feb 01; 26(2):240-6. PubMed ID: 9547862
    [Abstract] [Full Text] [Related]

  • 19. Role of the peroxisome proliferator-activated receptor alpha in responses to diisononyl phthalate.
    Valles EG, Laughter AR, Dunn CS, Cannelle S, Swanson CL, Cattley RC, Corton JC.
    Toxicology; 2003 Sep 30; 191(2-3):211-25. PubMed ID: 12965124
    [Abstract] [Full Text] [Related]

  • 20. Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice.
    Aleksunes LM, Klaassen CD.
    Drug Metab Dispos; 2012 Jul 30; 40(7):1366-79. PubMed ID: 22496397
    [Abstract] [Full Text] [Related]

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