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Journal Abstract Search

302 related items for PubMed ID: 19859563

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  • 2. GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.
    Beauchamp E, Bulut G, Abaan O, Chen K, Merchant A, Matsui W, Endo Y, Rubin JS, Toretsky J, Uren A.
    J Biol Chem; 2009 Apr 03; 284(14):9074-82. PubMed ID: 19189974
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  • 3. The EWS/FLI1 oncogenic transcription factor deregulates GLI1.
    Zwerner JP, Joo J, Warner KL, Christensen L, Hu-Lieskovan S, Triche TJ, May WA.
    Oncogene; 2008 May 22; 27(23):3282-91. PubMed ID: 18084326
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  • 7. Inhibition of platelet-derived growth factor-induced cell growth signaling by a short interfering RNA for EWS-Fli1 via down-regulation of phospholipase D2 in Ewing sarcoma cells.
    Nozawa S, Ohno T, Banno Y, Dohjima T, Wakahara K, Fan DG, Shimizu K.
    J Biol Chem; 2005 Jul 29; 280(30):27544-51. PubMed ID: 15919668
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  • 8. Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.
    Grohar PJ, Woldemichael GM, Griffin LB, Mendoza A, Chen QR, Yeung C, Currier DG, Davis S, Khanna C, Khan J, McMahon JB, Helman LJ.
    J Natl Cancer Inst; 2011 Jun 22; 103(12):962-78. PubMed ID: 21653923
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  • 9. Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.
    Gierisch ME, Pfistner F, Lopez-Garcia LA, Harder L, Schäfer BW, Niggli FK.
    J Biol Chem; 2016 Dec 23; 291(52):26922-26933. PubMed ID: 27875302
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  • 10. Stable interference of EWS-FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target.
    Herrero-Martín D, Osuna D, Ordóñez JL, Sevillano V, Martins AS, Mackintosh C, Campos M, Madoz-Gúrpide J, Otero-Motta AP, Caballero G, Amaral AT, Wai DH, Braun Y, Eisenacher M, Schaefer KL, Poremba C, de Alava E.
    Br J Cancer; 2009 Jul 07; 101(1):80-90. PubMed ID: 19491900
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  • 11. Ecteinascidin 743 interferes with the activity of EWS-FLI1 in Ewing sarcoma cells.
    Grohar PJ, Griffin LB, Yeung C, Chen QR, Pommier Y, Khanna C, Khan J, Helman LJ.
    Neoplasia; 2011 Feb 07; 13(2):145-53. PubMed ID: 21403840
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  • 14. A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis.
    Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF.
    Dis Model Mech; 2012 Jan 07; 5(1):95-106. PubMed ID: 21979944
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  • 15. Targeting CD99 Compromises the Oncogenic Effects of the Chimera EWS-FLI1 by Inducing Reexpression of Zyxin and Inhibition of GLI1 Activity.
    Balestra T, Manara MC, Laginestra MA, Pasello M, De Feo A, Bassi C, Guerzoni C, Landuzzi L, Lollini PL, Donati DM, Negrini M, Magnani M, Scotlandi K.
    Mol Cancer Ther; 2022 Jan 07; 21(1):58-69. PubMed ID: 34667115
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  • 16. BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
    Loganathan SN, Tang N, Fleming JT, Ma Y, Guo Y, Borinstein SC, Chiang C, Wang J.
    Oncotarget; 2016 Jul 12; 7(28):43504-43517. PubMed ID: 27259270
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  • 17. A molecular function map of Ewing's sarcoma.
    Kauer M, Ban J, Kofler R, Walker B, Davis S, Meltzer P, Kovar H.
    PLoS One; 2009 Jul 12; 4(4):e5415. PubMed ID: 19404404
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  • 18. The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors.
    Mendiola M, Carrillo J, García E, Lalli E, Hernández T, de Alava E, Tirode F, Delattre O, García-Miguel P, López-Barea F, Pestaña A, Alonso J.
    Int J Cancer; 2006 Mar 15; 118(6):1381-9. PubMed ID: 16206264
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  • 19. High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability.
    He T, Surdez D, Rantala JK, Haapa-Paananen S, Ban J, Kauer M, Tomazou E, Fey V, Alonso J, Kovar H, Delattre O, Iljin K.
    Gene; 2017 Jan 05; 596():137-146. PubMed ID: 27760381
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  • 20. EWS-FLI1-mediated suppression of the RAS-antagonist Sprouty 1 (SPRY1) confers aggressiveness to Ewing sarcoma.
    Cidre-Aranaz F, Grünewald TG, Surdez D, García-García L, Carlos Lázaro J, Kirchner T, González-González L, Sastre A, García-Miguel P, López-Pérez SE, Monzón S, Delattre O, Alonso J.
    Oncogene; 2017 Feb 09; 36(6):766-776. PubMed ID: 27375017
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