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127 related items for PubMed ID: 19859976
1. Methionine gamma-lyase: the unique reaction mechanism, physiological roles, and therapeutic applications against infectious diseases and cancers. Sato D, Nozaki T. IUBMB Life; 2009 Nov; 61(11):1019-28. PubMed ID: 19859976 [Abstract] [Full Text] [Related]
2. Kinetic characterization of methionine gamma-lyases from the enteric protozoan parasite Entamoeba histolytica against physiological substrates and trifluoromethionine, a promising lead compound against amoebiasis. Sato D, Yamagata W, Harada S, Nozaki T. FEBS J; 2008 Feb; 275(3):548-60. PubMed ID: 18199285 [Abstract] [Full Text] [Related]
3. Identification and characterization of two isoenzymes of methionine gamma-lyase from Entamoeba histolytica: a key enzyme of sulfur-amino acid degradation in an anaerobic parasitic protist that lacks forward and reverse trans-sulfuration pathways. Tokoro M, Asai T, Kobayashi S, Takeuchi T, Nozaki T. J Biol Chem; 2003 Oct 24; 278(43):42717-27. PubMed ID: 12920135 [Abstract] [Full Text] [Related]
8. Trifluoromethionine, a prodrug designed against methionine gamma-lyase-containing pathogens, has efficacy in vitro and in vivo against Trichomonas vaginalis. Coombs GH, Mottram JC. Antimicrob Agents Chemother; 2001 Jun 24; 45(6):1743-5. PubMed ID: 11353620 [Abstract] [Full Text] [Related]
9. Mechanism of trifluoromethionine resistance in Entamoeba histolytica. Penuliar GM, Furukawa A, Sato D, Nozaki T. J Antimicrob Chemother; 2011 Sep 24; 66(9):2045-52. PubMed ID: 21676903 [Abstract] [Full Text] [Related]
10. High expression, purification, and properties of recombinant homocysteine alpha, gamma-lyase. Han Q, Lenz M, Tan Y, Xu M, Sun X, Tan X, Tan X, Tang L, Miljkovic D, Hoffman RM. Protein Expr Purif; 1998 Nov 24; 14(2):267-74. PubMed ID: 9790890 [Abstract] [Full Text] [Related]
11. Overexpression and large-scale production of recombinant L-methionine-alpha-deamino-gamma-mercaptomethane-lyase for novel anticancer therapy. Tan Y, Xu M, Tan X, Tan X, Wang X, Saikawa Y, Nagahama T, Sun X, Lenz M, Hoffman RM. Protein Expr Purif; 1997 Mar 24; 9(2):233-45. PubMed ID: 9056489 [Abstract] [Full Text] [Related]
13. Crystallization and preliminary X-ray analysis of L-methionine gamma-lyase 1 from Entamoeba histolytica. Sato D, Karaki T, Shimizu A, Kamei K, Harada S, Nozaki T. Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Aug 01; 64(Pt 8):697-9. PubMed ID: 18678935 [Abstract] [Full Text] [Related]
14. L-Methionine-gamma-lyase, as a target to inhibit malodorous bacterial growth by trifluoromethionine. Yoshimura M, Nakano Y, Koga T. Biochem Biophys Res Commun; 2002 Apr 12; 292(4):964-8. PubMed ID: 11944909 [Abstract] [Full Text] [Related]