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100 related items for PubMed ID: 19875205

  • 1. Sigma-1 ligands: Tic-hydantoin as a key pharmacophore.
    Toussaint M, Mousset D, Foulon C, Jacquemard U, Vaccher C, Melnyk P.
    Eur J Med Chem; 2010 Jan; 45(1):256-63. PubMed ID: 19875205
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and pharmacological evaluation of Tic-hydantoin derivatives as selective sigma1 ligands. Part 2.
    Cazenave Gassiot A, Charton J, Girault-Mizzi S, Gilleron P, Debreu-Fontaine MA, Sergheraert C, Melnyk P.
    Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4828-32. PubMed ID: 16140009
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and pharmacological evaluation of Tic-hydantoin derivatives as selective sigma1 ligands. Part 1.
    Charton J, Cazenave Gassiot A, Girault-Mizzi S, Debreu-Fontaine MA, Melnyk P, Sergheraert C.
    Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4833-7. PubMed ID: 16140011
    [Abstract] [Full Text] [Related]

  • 4. Separation of Tic-hydantoin enantiomers, potent sigma-1 agonists, by high performance liquid chromatography and capillary electrophoresis.
    Cabordery AC, Toussaint M, Bonte JP, Melnyk P, Vaccher C, Foulon C.
    J Chromatogr A; 2010 Jun 11; 1217(24):3871-5. PubMed ID: 20451916
    [Abstract] [Full Text] [Related]

  • 5. Tic hydantoin sigma-1 agonist: pharmacological characterization on cocaine-induced stimulant and appetitive effects.
    Toussaint M, Delair B, Foulon C, Lempereur N, Vaccher C, Maurice T, Melnyk P.
    Eur Neuropsychopharmacol; 2009 Jul 11; 19(7):504-15. PubMed ID: 19249191
    [Abstract] [Full Text] [Related]

  • 6. Receptor site topographies for phencyclidine-like and sigma drugs: predictions from quantitative conformational, electrostatic potential, and radioreceptor analyses.
    Manallack DT, Wong MG, Costa M, Andrews PR, Beart PM.
    Mol Pharmacol; 1988 Dec 11; 34(6):863-79. PubMed ID: 2849051
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and structure-affinity relationships of novel spirocyclic sigma receptor ligands with furopyrazole structure.
    Schläger T, Schepmann D, Würthwein EU, Wünsch B.
    Bioorg Med Chem; 2008 Mar 15; 16(6):2992-3001. PubMed ID: 18221879
    [Abstract] [Full Text] [Related]

  • 8. Hydantoin-substituted 4,6-dichloroindole-2-carboxylic acids as ligands with high affinity for the glycine binding site of the NMDA receptor.
    Jansen M, Potschka H, Brandt C, Löscher W, Dannhardt G.
    J Med Chem; 2003 Jan 02; 46(1):64-73. PubMed ID: 12502360
    [Abstract] [Full Text] [Related]

  • 9. New synthesis of tic-hydantoins sigma-1 ligands and pharmacological evaluation on cocaine-induced stimulant effects.
    Toussaint M, Debreu-Fontaine MA, Maurice T, Melnyk P.
    Med Chem; 2010 Nov 02; 6(6):355-73. PubMed ID: 20843289
    [Abstract] [Full Text] [Related]

  • 10. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
    Berardi F, Abate C, Ferorelli S, Uricchio V, Colabufo NA, Niso M, Perrone R.
    J Med Chem; 2009 Dec 10; 52(23):7817-28. PubMed ID: 19842660
    [Abstract] [Full Text] [Related]

  • 11. Substituted benzo[d]oxazol-2(3H)-one derivatives with preference for the sigma1 binding site.
    Zampieri D, Grazia Mamolo M, Laurini E, Zanette C, Florio C, Collina S, Rossi D, Azzolina O, Vio L.
    Eur J Med Chem; 2009 Jan 10; 44(1):124-30. PubMed ID: 18440098
    [Abstract] [Full Text] [Related]

  • 12. Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling.
    Banister SD, Moussa IA, Jordan MJ, Coster MJ, Kassiou M.
    Bioorg Med Chem Lett; 2010 Jan 01; 20(1):145-8. PubMed ID: 19954972
    [Abstract] [Full Text] [Related]

  • 13. Thioxanthene-derived analogs as sigma(1) receptor ligands.
    Glennon RA, Ismaiel AM, Ablordeppey S, El-Ashmawy M, Fisher JB.
    Bioorg Med Chem Lett; 2004 May 03; 14(9):2217-20. PubMed ID: 15081012
    [Abstract] [Full Text] [Related]

  • 14. Molecular modeling of sigma 1 receptor ligands: a model of binding conformational and electrostatic considerations.
    Gund TM, Floyd J, Jung D.
    J Mol Graph Model; 2004 Jan 03; 22(3):221-30. PubMed ID: 14629980
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl carbamate analogs as sigma2 receptor ligands.
    Vangveravong S, Xu J, Zeng C, Mach RH.
    Bioorg Med Chem; 2006 Oct 15; 14(20):6988-97. PubMed ID: 16837201
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine sigma ligands as potential antipsychotic drugs.
    Nakazato A, Ohta K, Sekiguchi Y, Okuyama S, Chaki S, Kawashima Y, Hatayama K.
    J Med Chem; 1999 Mar 25; 42(6):1076-87. PubMed ID: 10090790
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and evaluation of tetrahydroindazole derivatives as sigma-2 receptor ligands.
    Wu ZW, Song SY, Li L, Lu HL, Lieberman B, Huang YS, Mach RH.
    Bioorg Med Chem; 2015 Apr 01; 23(7):1463-71. PubMed ID: 25752422
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of sigma receptor ligands with unsymmetrical spiro connection of the piperidine moiety.
    Jasper A, Schepmann D, Lehmkuhl K, Vela JM, Buschmann H, Holenz J, Wünsch B.
    Eur J Med Chem; 2009 Nov 01; 44(11):4306-14. PubMed ID: 19709783
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for sigma(1) receptor ligands based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives.
    Zampieri D, Mamolo MG, Laurini E, Florio C, Zanette C, Fermeglia M, Posocco P, Paneni MS, Pricl S, Vio L.
    J Med Chem; 2009 Sep 10; 52(17):5380-93. PubMed ID: 19673530
    [Abstract] [Full Text] [Related]

  • 20. Synthesis of novel sigma-receptor ligands from methyl alpha-D-mannopyranoside.
    Wiedemeyer K, Wünsch B.
    Carbohydr Res; 2006 Oct 16; 341(14):2321-34. PubMed ID: 16854396
    [Abstract] [Full Text] [Related]

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