These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

124 related items for PubMed ID: 19894728

  • 1. The discodermolide hairpin structure flows from conformationally stable modular motifs.
    Jogalekar AS, Kriel FH, Shi Q, Cornett B, Cicero D, Snyder JP.
    J Med Chem; 2010 Jan 14; 53(1):155-65. PubMed ID: 19894728
    [Abstract] [Full Text] [Related]

  • 2. The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatin.
    Canales A, Matesanz R, Gardner NM, Andreu JM, Paterson I, Díaz JF, Jiménez-Barbero J.
    Chemistry; 2008 Jan 14; 14(25):7557-69. PubMed ID: 18449868
    [Abstract] [Full Text] [Related]

  • 3.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 4. Differential effects of natural product microtubule stabilizers on microtubule assembly: single agent and combination studies with taxol, epothilone B, and discodermolide.
    Gertsch J, Meier S, Müller M, Altmann KH.
    Chembiochem; 2009 Jan 05; 10(1):166-75. PubMed ID: 19058273
    [Abstract] [Full Text] [Related]

  • 5. The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide.
    Sánchez-Pedregal VM, Kubicek K, Meiler J, Lyothier I, Paterson I, Carlomagno T.
    Angew Chem Int Ed Engl; 2006 Nov 13; 45(44):7388-94. PubMed ID: 17036370
    [No Abstract] [Full Text] [Related]

  • 6.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 7.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 8. Conception, synthesis, and biological evaluation of original discodermolide analogues.
    de Lemos E, Agouridas E, Sorin G, Guerreiro A, Commerçon A, Pancrazi A, Betzer JF, Lannou MI, Ardisson J.
    Chemistry; 2011 Aug 29; 17(36):10123-34. PubMed ID: 21793059
    [Abstract] [Full Text] [Related]

  • 9. Total synthesis and biological evaluation of potent analogues of dictyostatin: modification of the C2-C6 dienoate region.
    Paterson I, Gardner NM, Guzmán E, Wright AE.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6268-72. PubMed ID: 18951787
    [Abstract] [Full Text] [Related]

  • 10.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 11. Total synthesis of the potent microtubule-stabilizing agent (+)-discodermolide.
    Harried SS, Lee CP, Yang G, Lee TI, Myles DC.
    J Org Chem; 2003 Aug 22; 68(17):6646-60. PubMed ID: 12919029
    [Abstract] [Full Text] [Related]

  • 12. Toward understanding how the lactone moiety of discodermolide affects activity.
    Shaw SJ, Sundermann KF, Burlingame MA, Myles DC, Freeze BS, Xian M, Brouard I, Smith AB.
    J Am Chem Soc; 2005 May 11; 127(18):6532-3. PubMed ID: 15869264
    [Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14. Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence.
    Guo B, Rodriguez-Gabin A, Prota AE, Mühlethaler T, Zhang N, Ye K, Steinmetz MO, Horwitz SB, Smith AB, McDaid HM.
    Mol Pharmacol; 2020 Aug 11; 98(2):156-167. PubMed ID: 32591477
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C7 hydroxyl, and the lactone.
    Smith AB, Xian M.
    Org Lett; 2005 Nov 10; 7(23):5229-32. PubMed ID: 16268545
    [Abstract] [Full Text] [Related]

  • 16. Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.
    Khrapunovich-Baine M, Menon V, Verdier-Pinard P, Smith AB, Angeletti RH, Fiser A, Horwitz SB, Xiao H.
    Biochemistry; 2009 Dec 15; 48(49):11664-77. PubMed ID: 19863156
    [Abstract] [Full Text] [Related]

  • 17. The structure activity relationship of discodermolide analogues.
    Shaw SJ.
    Mini Rev Med Chem; 2008 Mar 15; 8(3):276-84. PubMed ID: 18336347
    [Abstract] [Full Text] [Related]

  • 18. Semisynthetic analogues of the microtubule-stabilizing agent discodermolide: preparation and biological activity.
    Gunasekera SP, Longley RE, Isbrucker RA.
    J Nat Prod; 2002 Dec 15; 65(12):1830-7. PubMed ID: 12502323
    [Abstract] [Full Text] [Related]

  • 19. Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin.
    Florence GJ, Gardner NM, Paterson I.
    Nat Prod Rep; 2008 Apr 15; 25(2):342-75. PubMed ID: 18389141
    [Abstract] [Full Text] [Related]

  • 20. Design, total synthesis, and evaluation of C13-C14 cyclopropane analogues of (+)-discodermolide.
    Smith AB, Xian M, Liu F.
    Org Lett; 2005 Oct 13; 7(21):4613-6. PubMed ID: 16209492
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 7.