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Journal Abstract Search

737 related items for PubMed ID: 19906529

  • 1. Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors.
    Angibaud P, Van Emelen K, Decrane L, van Brandt S, Ten Holte P, Pilatte I, Roux B, Poncelet V, Speybrouck D, Queguiner L, Gaurrand S, Mariën A, Floren W, Janssen L, Verdonck M, van Dun J, van Gompel J, Gilissen R, Mackie C, Du Jardin M, Peeters J, Noppe M, Van Hijfte L, Freyne E, Page M, Janicot M, Arts J.
    Bioorg Med Chem Lett; 2010 Jan 01; 20(1):294-8. PubMed ID: 19906529
    [Abstract] [Full Text] [Related]

  • 2. New aryldithiolethione derivatives as potent histone deacetylase inhibitors.
    Tazzari V, Cappelletti G, Casagrande M, Perrino E, Renzi L, Del Soldato P, Sparatore A.
    Bioorg Med Chem; 2010 Jun 15; 18(12):4187-94. PubMed ID: 20576572
    [Abstract] [Full Text] [Related]

  • 3. Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors.
    Rossi C, Porcelloni M, D'Andrea P, Fincham CI, Ettorre A, Mauro S, Squarcia A, Bigioni M, Parlani M, Nardelli F, Binaschi M, Maggi CA, Fattori D.
    Bioorg Med Chem Lett; 2011 Apr 15; 21(8):2305-8. PubMed ID: 21420859
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel Histone deacetylases (HDACs) inhibitors.
    Zhang Y, Feng J, Liu C, Zhang L, Jiao J, Fang H, Su L, Zhang X, Zhang J, Li M, Wang B, Xu W.
    Bioorg Med Chem; 2010 Mar 01; 18(5):1761-72. PubMed ID: 20171895
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and preliminary bioactivity studies of 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors.
    Guan P, Sun F, Hou X, Wang F, Yi F, Xu W, Fang H.
    Bioorg Med Chem; 2012 Jun 15; 20(12):3865-72. PubMed ID: 22579621
    [Abstract] [Full Text] [Related]

  • 6. Design and synthesis of aryl ether and sulfone hydroxamic acids as potent histone deacetylase (HDAC) inhibitors.
    Pabba C, Gregg BT, Kitchen DB, Chen ZJ, Judkins A.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):324-8. PubMed ID: 21109435
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological characterization of amidopropenyl hydroxamates as HDAC inhibitors.
    Thaler F, Varasi M, Colombo A, Boggio R, Munari D, Regalia N, Rozio MG, Reali V, Resconi AE, Mai A, Gagliardi S, Dondio G, Minucci S, Mercurio C.
    ChemMedChem; 2010 Aug 02; 5(8):1359-72. PubMed ID: 20572281
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity.
    Chetan B, Bunha M, Jagrat M, Sinha BN, Saiko P, Graser G, Szekeres T, Raman G, Rajendran P, Moorthy D, Basu A, Jayaprakash V.
    Bioorg Med Chem Lett; 2010 Jul 01; 20(13):3906-10. PubMed ID: 20605448
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and antitumor activity of novel diaryl ether hydroxamic acids derivatives as potential HDAC inhibitors.
    Zhu Y, Chen X, Wu Z, Zheng Y, Chen Y, Tang W, Lu T.
    Arch Pharm Res; 2012 Oct 01; 35(10):1723-32. PubMed ID: 23139122
    [Abstract] [Full Text] [Related]

  • 10. Benzothiazole-containing hydroxamic acids as histone deacetylase inhibitors and antitumor agents.
    Oanh DT, Hai HV, Park SH, Kim HJ, Han BW, Kim HS, Hong JT, Han SB, Hue VT, Nam NH.
    Bioorg Med Chem Lett; 2011 Dec 15; 21(24):7509-12. PubMed ID: 22036991
    [Abstract] [Full Text] [Related]

  • 11. Histone deacetylase inhibitors with a primary amide zinc binding group display antitumor activity in xenograft model.
    Attenni B, Ontoria JM, Cruz JC, Rowley M, Schultz-Fademrecht C, Steinkühler C, Jones P.
    Bioorg Med Chem Lett; 2009 Jun 01; 19(11):3081-4. PubMed ID: 19410459
    [Abstract] [Full Text] [Related]

  • 12. The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors.
    Shultz M, Fan J, Chen C, Cho YS, Davis N, Bickford S, Buteau K, Cao X, Holmqvist M, Hsu M, Jiang L, Liu G, Lu Q, Patel C, Suresh JR, Selvaraj M, Urban L, Wang P, Yan-Neale Y, Whitehead L, Zhang H, Zhou L, Atadja P.
    Bioorg Med Chem Lett; 2011 Aug 15; 21(16):4909-12. PubMed ID: 21742496
    [Abstract] [Full Text] [Related]

  • 13. Design and synthesis of novel pyrimidine hydroxamic acid inhibitors of histone deacetylases.
    Donald AD, Clark VL, Patel S, Day FA, Rowlands MG, Wibata J, Stimson L, Hardcastle A, Eccles SA, McNamara D, Needham LA, Raynaud FI, Aherne W, Moffat DF.
    Bioorg Med Chem Lett; 2010 Nov 15; 20(22):6657-60. PubMed ID: 20884208
    [Abstract] [Full Text] [Related]

  • 14. Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates.
    Suzuki T, Nagano Y, Kouketsu A, Matsuura A, Maruyama S, Kurotaki M, Nakagawa H, Miyata N.
    J Med Chem; 2005 Feb 24; 48(4):1019-32. PubMed ID: 15715470
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of tyrosine-based hydroxamic acid analogs as novel histone deacetylases (HDACs) inhibitors.
    Zhang Y, Feng J, Liu C, Fang H, Xu W.
    Bioorg Med Chem; 2011 Aug 01; 19(15):4437-44. PubMed ID: 21733698
    [Abstract] [Full Text] [Related]

  • 16. 2-aroylindoles and 2-aroylbenzofurans with N-hydroxyacrylamide substructures as a novel series of rationally designed histone deacetylase inhibitors.
    Mahboobi S, Sellmer A, Höcher H, Garhammer C, Pongratz H, Maier T, Ciossek T, Beckers T.
    J Med Chem; 2007 Sep 06; 50(18):4405-18. PubMed ID: 17691763
    [Abstract] [Full Text] [Related]

  • 17. Modified cap group suberoylanilide hydroxamic acid histone deacetylase inhibitor derivatives reveal improved selective antileukemic activity.
    Salmi-Smail C, Fabre A, Dequiedt F, Restouin A, Castellano R, Garbit S, Roche P, Morelli X, Brunel JM, Collette Y.
    J Med Chem; 2010 Apr 22; 53(8):3038-47. PubMed ID: 20218673
    [Abstract] [Full Text] [Related]

  • 18. Amide-based derivatives of β-alanine hydroxamic acid as histone deacetylase inhibitors: attenuation of potency through resonance effects.
    Liao V, Liu T, Codd R.
    Bioorg Med Chem Lett; 2012 Oct 01; 22(19):6200-4. PubMed ID: 22932316
    [Abstract] [Full Text] [Related]

  • 19. Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors.
    Liu R, Wang J, Tang W, Fang H.
    Bioorg Med Chem; 2016 Apr 01; 24(7):1446-54. PubMed ID: 26907204
    [Abstract] [Full Text] [Related]

  • 20. Design and synthesis of novel isoxazole-based HDAC inhibitors.
    Conti P, Tamborini L, Pinto A, Sola L, Ettari R, Mercurio C, De Micheli C.
    Eur J Med Chem; 2010 Sep 01; 45(9):4331-8. PubMed ID: 20637529
    [Abstract] [Full Text] [Related]

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