These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

203 related items for PubMed ID: 19920197

  • 1. Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy.
    Fu L, Kim YA, Wang X, Wu X, Yue P, Lonial S, Khuri FR, Sun SY.
    Cancer Res; 2009 Dec 01; 69(23):8967-76. PubMed ID: 19920197
    [Abstract] [Full Text] [Related]

  • 2. Enhancing perifosine's anticancer efficacy by preventing autophagy.
    Sun SY.
    Autophagy; 2010 Jan 01; 6(1):184-5. PubMed ID: 20023422
    [Abstract] [Full Text] [Related]

  • 3. Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
    Cirstea D, Hideshima T, Rodig S, Santo L, Pozzi S, Vallet S, Ikeda H, Perrone G, Gorgun G, Patel K, Desai N, Sportelli P, Kapoor S, Vali S, Mukherjee S, Munshi NC, Anderson KC, Raje N.
    Mol Cancer Ther; 2010 Apr 01; 9(4):963-75. PubMed ID: 20371718
    [Abstract] [Full Text] [Related]

  • 4. Perifosine enhances mTORC1-targeted cancer therapy by activation of GSK3β in NSCLC cells.
    Ma Z, Zhu L, Luo X, Zhai S, Li P, Wang X.
    Cancer Biol Ther; 2012 Sep 01; 13(11):1009-17. PubMed ID: 22825337
    [Abstract] [Full Text] [Related]

  • 5. Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin.
    Liu D, Hou P, Liu Z, Wu G, Xing M.
    Cancer Res; 2009 Sep 15; 69(18):7311-9. PubMed ID: 19706758
    [Abstract] [Full Text] [Related]

  • 6. Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.
    Koo J, Wu X, Mao Z, Khuri FR, Sun SY.
    J Biol Chem; 2015 May 29; 290(22):14120-9. PubMed ID: 25897075
    [Abstract] [Full Text] [Related]

  • 7. Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation.
    Wang X, Yue P, Kim YA, Fu H, Khuri FR, Sun SY.
    Cancer Res; 2008 Sep 15; 68(18):7409-18. PubMed ID: 18794129
    [Abstract] [Full Text] [Related]

  • 8. Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction.
    Ito M, Yurube T, Kakutani K, Maeno K, Takada T, Terashima Y, Kakiuchi Y, Takeoka Y, Miyazaki S, Kuroda R, Nishida K.
    Osteoarthritis Cartilage; 2017 Dec 15; 25(12):2134-2146. PubMed ID: 28888905
    [Abstract] [Full Text] [Related]

  • 9. 3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells.
    Sun Y, Huang YH, Huang FY, Mei WL, Liu Q, Wang CC, Lin YY, Huang C, Li YN, Dai HF, Tan GH.
    Theranostics; 2018 Dec 15; 8(7):2044-2060. PubMed ID: 29556372
    [Abstract] [Full Text] [Related]

  • 10. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
    Elrod HA, Lin YD, Yue P, Wang X, Lonial S, Khuri FR, Sun SY.
    Mol Cancer Ther; 2007 Jul 15; 6(7):2029-38. PubMed ID: 17604333
    [Abstract] [Full Text] [Related]

  • 11. Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.
    Momota H, Nerio E, Holland EC.
    Cancer Res; 2005 Aug 15; 65(16):7429-35. PubMed ID: 16103096
    [Abstract] [Full Text] [Related]

  • 12. Alpinia katsumadai Hayata induces growth inhibition and autophagy‑related apoptosis by regulating the AMPK and Akt/mTOR/p70S6K signaling pathways in cancer cells.
    An W, Zhang Y, Lai H, Zhang Y, Zhang H, Zhao G, Liu M, Li Y, Lin X, Cao S.
    Oncol Rep; 2022 Aug 15; 48(2):. PubMed ID: 35730618
    [Abstract] [Full Text] [Related]

  • 13. Autophagy induced by cardamonin is associated with mTORC1 inhibition in SKOV3 cells.
    Shi D, Niu P, Heng X, Chen L, Zhu Y, Zhou J.
    Pharmacol Rep; 2018 Oct 15; 70(5):908-916. PubMed ID: 30099297
    [Abstract] [Full Text] [Related]

  • 14. mTOR Complex 2 Stabilizes Mcl-1 Protein by Suppressing Its Glycogen Synthase Kinase 3-Dependent and SCF-FBXW7-Mediated Degradation.
    Koo J, Yue P, Deng X, Khuri FR, Sun SY.
    Mol Cell Biol; 2015 Jul 15; 35(13):2344-55. PubMed ID: 25918246
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of mTOR complex 2 induces GSK3/FBXW7-dependent degradation of sterol regulatory element-binding protein 1 (SREBP1) and suppresses lipogenesis in cancer cells.
    Li S, Oh YT, Yue P, Khuri FR, Sun SY.
    Oncogene; 2016 Feb 04; 35(5):642-50. PubMed ID: 25893295
    [Abstract] [Full Text] [Related]

  • 16. Augmentation of NVP-BEZ235's anticancer activity against human lung cancer cells by blockage of autophagy.
    Xu CX, Zhao L, Yue P, Fang G, Tao H, Owonikoko TK, Ramalingam SS, Khuri FR, Sun SY.
    Cancer Biol Ther; 2011 Sep 15; 12(6):549-55. PubMed ID: 21738008
    [Abstract] [Full Text] [Related]

  • 17. SNS-032 inhibits mTORC1/mTORC2 activity in acute myeloid leukemia cells and has synergistic activity with perifosine against Akt.
    Meng H, Jin Y, Liu H, You L, Yang C, Yang X, Qian W.
    J Hematol Oncol; 2013 Feb 18; 6():18. PubMed ID: 23415012
    [Abstract] [Full Text] [Related]

  • 18. The short chain cell-permeable ceramide (C6) restores cell apoptosis and perifosine sensitivity in cultured glioblastoma cells.
    Qin LS, Yu ZQ, Zhang SM, Sun G, Zhu J, Xu J, Guo J, Fu LS.
    Mol Biol Rep; 2013 Oct 18; 40(10):5645-55. PubMed ID: 24065522
    [Abstract] [Full Text] [Related]

  • 19. Delicaflavone induces autophagic cell death in lung cancer via Akt/mTOR/p70S6K signaling pathway.
    Sui Y, Yao H, Li S, Jin L, Shi P, Li Z, Wang G, Lin S, Wu Y, Li Y, Huang L, Liu Q, Lin X.
    J Mol Med (Berl); 2017 Mar 18; 95(3):311-322. PubMed ID: 27838742
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of Autophagy Increases Proliferation Inhibition and Apoptosis Induced by the PI3K/mTOR Inhibitor NVP-BEZ235 in Breast Cancer Cells.
    Ji Y, Di W, Yang Q, Lu Z, Cai W, Wu J.
    Clin Lab; 2015 Mar 18; 61(8):1043-51. PubMed ID: 26427150
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 11.