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Journal Abstract Search

472 related items for PubMed ID: 19923256

  • 1. Identification of novel substrates for human cytochrome P450 2J2.
    Lee CA, Neul D, Clouser-Roche A, Dalvie D, Wester MR, Jiang Y, Jones JP, Freiwald S, Zientek M, Totah RA.
    Drug Metab Dispos; 2010 Feb; 38(2):347-56. PubMed ID: 19923256
    [Abstract] [Full Text] [Related]

  • 2. Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Lee CA, Jones JP, Katayama J, Kaspera R, Jiang Y, Freiwald S, Smith E, Walker GS, Totah RA.
    Drug Metab Dispos; 2012 May; 40(5):943-51. PubMed ID: 22328583
    [Abstract] [Full Text] [Related]

  • 3. Danazol Inhibits Cytochrome P450 2J2 Activity in a Substrate-independent Manner.
    Lee E, Wu Z, Shon JC, Liu KH.
    Drug Metab Dispos; 2015 Aug; 43(8):1250-3. PubMed ID: 26048912
    [Abstract] [Full Text] [Related]

  • 4. Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.
    Bakken GV, Molden E, Knutsen K, Lunder N, Hermann M.
    Drug Metab Dispos; 2012 Sep; 40(9):1778-84. PubMed ID: 22688609
    [Abstract] [Full Text] [Related]

  • 5. Terfenadone is a strong inhibitor of CYP2J2 present in the human liver and intestinal microsomes.
    Lee E, Kim JH, Shon JC, Wu Z, Kim HJ, Gim M, Lee T, Liu KH.
    Drug Metab Pharmacokinet; 2018 Jun; 33(3):159-163. PubMed ID: 29759885
    [Abstract] [Full Text] [Related]

  • 6. Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole.
    Matsumoto S, Hirama T, Matsubara T, Nagata K, Yamazoe Y.
    Drug Metab Dispos; 2002 Nov; 30(11):1240-5. PubMed ID: 12386130
    [Abstract] [Full Text] [Related]

  • 7. Multiple modes of inhibition of human cytochrome P450 2J2 by dronedarone, amiodarone and their active metabolites.
    Karkhanis A, Lam HY, Venkatesan G, Koh SK, Chai CL, Zhou L, Hong Y, Kojodjojo P, Chan EC.
    Biochem Pharmacol; 2016 May 01; 107():67-80. PubMed ID: 26972388
    [Abstract] [Full Text] [Related]

  • 8. Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes.
    Hashizume T, Imaoka S, Mise M, Terauchi Y, Fujii T, Miyazaki H, Kamataki T, Funae Y.
    J Pharmacol Exp Ther; 2002 Jan 01; 300(1):298-304. PubMed ID: 11752129
    [Abstract] [Full Text] [Related]

  • 9. Unusual regioselectivity and active site topology of human cytochrome P450 2J2.
    Lafite P, André F, Zeldin DC, Dansette PM, Mansuy D.
    Biochemistry; 2007 Sep 11; 46(36):10237-47. PubMed ID: 17705402
    [Abstract] [Full Text] [Related]

  • 10. CYP2J2 and CYP2C19 are the major enzymes responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems.
    Wu Z, Lee D, Joo J, Shin JH, Kang W, Oh S, Lee DY, Lee SJ, Yea SS, Lee HS, Lee T, Liu KH.
    Antimicrob Agents Chemother; 2013 Nov 11; 57(11):5448-56. PubMed ID: 23959307
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of methadone and levo-alpha-acetylmethadol (LAAM) by human intestinal cytochrome P450 3A4 (CYP3A4): potential contribution of intestinal metabolism to presystemic clearance and bioactivation.
    Oda Y, Kharasch ED.
    J Pharmacol Exp Ther; 2001 Sep 11; 298(3):1021-32. PubMed ID: 11504799
    [Abstract] [Full Text] [Related]

  • 12. Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes.
    Evangelista EA, Kaspera R, Mokadam NA, Jones JP, Totah RA.
    Drug Metab Dispos; 2013 Dec 11; 41(12):2087-94. PubMed ID: 24021950
    [Abstract] [Full Text] [Related]

  • 13. In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies.
    Wang L, Zhang D, Raghavan N, Yao M, Ma L, Frost CE, Maxwell BD, Chen SY, He K, Goosen TC, Humphreys WG, Grossman SJ.
    Drug Metab Dispos; 2010 Mar 11; 38(3):448-58. PubMed ID: 19940026
    [Abstract] [Full Text] [Related]

  • 14. Molecular determinant of substrate binding and specificity of cytochrome P450 2J2.
    Xu L, Chen LY.
    Sci Rep; 2020 Dec 17; 10(1):22267. PubMed ID: 33335233
    [Abstract] [Full Text] [Related]

  • 15. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
    Casabar RC, Wallace AD, Hodgson E, Rose RL.
    Drug Metab Dispos; 2006 Oct 17; 34(10):1779-85. PubMed ID: 16855053
    [Abstract] [Full Text] [Related]

  • 16. Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Ren S, Zeng J, Mei Y, Zhang JZ, Yan SF, Fei J, Chen L.
    Drug Metab Dispos; 2013 Jan 17; 41(1):60-71. PubMed ID: 23033255
    [Abstract] [Full Text] [Related]

  • 17. Identification of human cytochrome P450 enzymes involved in the hepatic and intestinal biotransformation of 20(S)-protopanaxadiol.
    Chiu NT, Tomlinson Guns ES, Adomat H, Jia W, Deb S.
    Biopharm Drug Dispos; 2014 Mar 17; 35(2):104-18. PubMed ID: 24151189
    [Abstract] [Full Text] [Related]

  • 18. Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: major roles for CYP2J2 and CYP3A.
    Liu KH, Kim MG, Lee DJ, Yoon YJ, Kim MJ, Shon JH, Choi CS, Choi YK, Desta Z, Shin JG.
    Drug Metab Dispos; 2006 Nov 17; 34(11):1793-7. PubMed ID: 16896065
    [Abstract] [Full Text] [Related]

  • 19. Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.
    Ghosal A, Lu X, Penner N, Gao L, Ramanathan R, Chowdhury SK, Kishnani NS, Alton KB.
    Drug Metab Dispos; 2011 Jan 17; 39(1):30-8. PubMed ID: 20926621
    [Abstract] [Full Text] [Related]

  • 20. Evidence of significant contribution from CYP3A5 to hepatic drug metabolism.
    Huang W, Lin YS, McConn DJ, Calamia JC, Totah RA, Isoherranen N, Glodowski M, Thummel KE.
    Drug Metab Dispos; 2004 Dec 17; 32(12):1434-45. PubMed ID: 15383492
    [Abstract] [Full Text] [Related]

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