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105 related items for PubMed ID: 19950984

  • 1. Role of glutathione transferases in the mechanism of brostallicin activation.
    Pezzola S, Antonini G, Geroni C, Beria I, Colombo M, Broggini M, Marchini S, Mongelli N, Leboffe L, MacArthur R, Mozzi AF, Federici G, Caccuri AM.
    Biochemistry; 2010 Jan 12; 49(1):226-35. PubMed ID: 19950984
    [Abstract] [Full Text] [Related]

  • 2. Brostallicin, a novel anticancer agent whose activity is enhanced upon binding to glutathione.
    Geroni C, Marchini S, Cozzi P, Galliera E, Ragg E, Colombo T, Battaglia R, Howard M, D'Incalci M, Broggini M.
    Cancer Res; 2002 Apr 15; 62(8):2332-6. PubMed ID: 11956092
    [Abstract] [Full Text] [Related]

  • 3. Cytotoxic alpha-halogenoacrylic derivatives of distamycin A and congeners.
    Beria I, Baraldi PG, Cozzi P, Caldarelli M, Geroni C, Marchini S, Mongelli N, Romagnoli R.
    J Med Chem; 2004 May 06; 47(10):2611-23. PubMed ID: 15115402
    [Abstract] [Full Text] [Related]

  • 4. Expression of human mu or alpha class glutathione S-transferases in stably transfected human MCF-7 breast cancer cells: effect on cellular sensitivity to cytotoxic agents.
    Townsend AJ, Tu CP, Cowan KH.
    Mol Pharmacol; 1992 Feb 06; 41(2):230-6. PubMed ID: 1538704
    [Abstract] [Full Text] [Related]

  • 5. Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases.
    Federici L, Lo Sterzo C, Pezzola S, Di Matteo A, Scaloni F, Federici G, Caccuri AM.
    Cancer Res; 2009 Oct 15; 69(20):8025-34. PubMed ID: 19808963
    [Abstract] [Full Text] [Related]

  • 6. Brostallicin (PNU-166196), a new minor groove DNA binder: preclinical and clinical activity.
    Lorusso D, Mainenti S, Pietragalla A, Ferrandina G, Foco G, Masciullo V, Scambia G.
    Expert Opin Investig Drugs; 2009 Dec 15; 18(12):1939-46. PubMed ID: 19938904
    [Abstract] [Full Text] [Related]

  • 7. Antineoplastic drug sensitivity of human MCF-7 breast cancer cells stably transfected with a human alpha class glutathione S-transferase gene.
    Leyland-Jones BR, Townsend AJ, Tu CP, Cowan KH, Goldsmith ME.
    Cancer Res; 1991 Jan 15; 51(2):587-94. PubMed ID: 1985777
    [Abstract] [Full Text] [Related]

  • 8. Human renal UOK130 tumor cells: a drug resistant cell line with highly selective over-expression of glutathione S-transferase-pi isozyme.
    Wang W, Liu G, Zheng J.
    Eur J Pharmacol; 2007 Jul 30; 568(1-3):61-7. PubMed ID: 17509556
    [Abstract] [Full Text] [Related]

  • 9. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.
    Nelson CP, Kidd LC, Sauvageot J, Isaacs WB, De Marzo AM, Groopman JD, Nelson WG, Kensler TW.
    Cancer Res; 2001 Jan 01; 61(1):103-9. PubMed ID: 11196146
    [Abstract] [Full Text] [Related]

  • 10. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance.
    Hayes JD, Pulford DJ.
    Crit Rev Biochem Mol Biol; 1995 Jan 01; 30(6):445-600. PubMed ID: 8770536
    [Abstract] [Full Text] [Related]

  • 11. Enhancement of in vivo antitumor activity of classical anticancer agents by combination with the new, glutathione-interacting DNA minor groove-binder, brostallicin.
    Sabatino MA, Colombo T, Geroni C, Marchini S, Broggini M.
    Clin Cancer Res; 2003 Nov 01; 9(14):5402-8. PubMed ID: 14614026
    [Abstract] [Full Text] [Related]

  • 12. Zebularine partially reverses GST methylation in prostate cancer cells and restores sensitivity to the DNA minor groove binder brostallicin.
    Sabatino MA, Geroni C, Ganzinelli M, Ceruti R, Broggini M.
    Epigenetics; 2013 Jun 01; 8(6):656-65. PubMed ID: 23771052
    [Abstract] [Full Text] [Related]

  • 13. Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program.
    Tew KD, Monks A, Barone L, Rosser D, Akerman G, Montali JA, Wheatley JB, Schmidt DE.
    Mol Pharmacol; 1996 Jul 01; 50(1):149-59. PubMed ID: 8700107
    [Abstract] [Full Text] [Related]

  • 14. Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate.
    Cacciatore I, Caccuri AM, Cocco A, De Maria F, Di Stefano A, Luisi G, Pinnen F, Ricci G, Sozio P, Turella P.
    Amino Acids; 2005 Nov 01; 29(3):255-61. PubMed ID: 16082503
    [Abstract] [Full Text] [Related]

  • 15. Hepsulfam sensitivity in human breast cancer cell lines: the role of glutathione and glutathione S-transferase in resistance.
    Armstrong DK, Gordon GB, Hilton J, Streeper RT, Colvin OM, Davidson NE.
    Cancer Res; 1992 Mar 15; 52(6):1416-21. PubMed ID: 1540950
    [Abstract] [Full Text] [Related]

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  • 17. Arsenic trioxide in the mechanism of drug resistance reversal in MCF-7/ADM cell line of human breast cancer.
    Wang X, Kong L, Zhao J, Yang P.
    Zhonghua Zhong Liu Za Zhi; 2002 Jul 15; 24(4):339-43. PubMed ID: 12408759
    [Abstract] [Full Text] [Related]

  • 18. Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione.
    Dirven HA, van Ommen B, van Bladeren PJ.
    Cancer Res; 1994 Dec 01; 54(23):6215-20. PubMed ID: 7954469
    [Abstract] [Full Text] [Related]

  • 19. Amitriptyline may have a supportive role in cancer treatment by inhibiting glutathione S-transferase pi (GST-π) and alpha (GST-α).
    Kulaksiz-Erkmen G, Dalmizrak O, Dincsoy-Tuna G, Dogan A, Ogus IH, Ozer N.
    J Enzyme Inhib Med Chem; 2013 Feb 01; 28(1):131-6. PubMed ID: 22145766
    [Abstract] [Full Text] [Related]

  • 20. Proapoptotic activity of new glutathione S-transferase inhibitors.
    Turella P, Cerella C, Filomeni G, Bullo A, De Maria F, Ghibelli L, Ciriolo MR, Cianfriglia M, Mattei M, Federici G, Ricci G, Caccuri AM.
    Cancer Res; 2005 May 01; 65(9):3751-61. PubMed ID: 15867371
    [Abstract] [Full Text] [Related]

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