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PUBMED FOR HANDHELDS

Journal Abstract Search


115 related items for PubMed ID: 19954975

  • 1. Structure-activity relationships of N-substituted ligands for the alpha7 nicotinic acetylcholine receptor.
    Mortell KH, Schrimpf MR, Bunnelle WH, Anderson DJ, Gronlien JH, Hagene KT, Gopalakrishnan M.
    Bioorg Med Chem Lett; 2010 Jan 01; 20(1):104-7. PubMed ID: 19954975
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  • 2. Octahydropyrrolo[3,4-c]pyrrole: a diamine scaffold for construction of either alpha4beta2 or alpha7-selective nicotinic acetylcholine receptor (nAChR) ligands. Substitutions that switch subtype selectivity.
    Bunnelle WH, Tietje KR, Frost JM, Peters D, Ji J, Li T, Scanio MJ, Shi L, Anderson DJ, Dyhring T, Grønlien JH, Ween H, Thorin-Hagene K, Meyer MD.
    J Med Chem; 2009 Jul 23; 52(14):4126-41. PubMed ID: 19552432
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  • 7. Potential nicotinic acetylcholine receptor ligands from 2,4-methanoproline derivatives.
    Patel AB, Malpass JR.
    J Med Chem; 2008 Nov 13; 51(21):7005-9. PubMed ID: 18841955
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  • 8. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors.
    Bodnar AL, Cortes-Burgos LA, Cook KK, Dinh DM, Groppi VE, Hajos M, Higdon NR, Hoffmann WE, Hurst RS, Myers JK, Rogers BN, Wall TM, Wolfe ML, Wong E.
    J Med Chem; 2005 Feb 24; 48(4):905-8. PubMed ID: 15715459
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  • 9. JN403, in vitro characterization of a novel nicotinic acetylcholine receptor alpha7 selective agonist.
    Feuerbach D, Nozulak J, Lingenhoehl K, McAllister K, Hoyer D.
    Neurosci Lett; 2007 Apr 06; 416(1):61-5. PubMed ID: 17314009
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  • 10. In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile.
    Malysz J, Grønlien JH, Anderson DJ, Håkerud M, Thorin-Hagene K, Ween H, Wetterstrand C, Briggs CA, Faghih R, Bunnelle WH, Gopalakrishnan M.
    J Pharmacol Exp Ther; 2009 Jul 06; 330(1):257-67. PubMed ID: 19389923
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  • 14. Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors.
    Holladay MW, Wasicak JT, Lin NH, He Y, Ryther KB, Bannon AW, Buckley MJ, Kim DJ, Decker MW, Anderson DJ, Campbell JE, Kuntzweiler TA, Donnelly-Roberts DL, Piattoni-Kaplan M, Briggs CA, Williams M, Arneric SP.
    J Med Chem; 1998 Feb 12; 41(4):407-12. PubMed ID: 9484491
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  • 16. Discovery of a novel series of quinolone α7 nicotinic acetylcholine receptor agonists.
    McDonald IM, Mate RA, Zusi FC, Huang H, Post-Munson DJ, Ferrante MA, Gallagher L, Bertekap RL, Knox RJ, Robertson BJ, Harden DG, Morgan DG, Lodge NJ, Dworetzky SI, Olson RE, Macor JE.
    Bioorg Med Chem Lett; 2013 Mar 15; 23(6):1684-8. PubMed ID: 23414838
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  • 17. (R)-3'-(3-methylbenzo[b]thiophen-5-yl)spiro[1-azabicyclo[2,2,2]octane-3,5'-oxazolidin]-2'-one, a novel and potent alpha7 nicotinic acetylcholine receptor partial agonist displays cognitive enhancing properties.
    Tatsumi R, Fujio M, Takanashi S, Numata A, Katayama J, Satoh H, Shiigi Y, Maeda J, Kuriyama M, Horikawa T, Murozono T, Hashimoto K, Tanaka H.
    J Med Chem; 2006 Jul 13; 49(14):4374-83. PubMed ID: 16821797
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  • 20. 2-(Arylmethyl)-3-substituted quinuclidines as selective alpha 7 nicotinic receptor ligands.
    Mazurov A, Klucik J, Miao L, Phillips TY, Seamans A, Schmitt JD, Hauser TA, Johnson RT, Miller C.
    Bioorg Med Chem Lett; 2005 Apr 15; 15(8):2073-7. PubMed ID: 15808471
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