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Journal Abstract Search

143 related items for PubMed ID: 19961222

  • 21. Structure-based design and synthesis of substituted 2-butanols as nonpeptidic inhibitors of HIV protease: secondary amide series.
    Reich SH, Melnick M, Pino MJ, Fuhry MA, Trippe AJ, Appelt K, Davies JF, Wu BW, Musick L.
    J Med Chem; 1996 Jul 05; 39(14):2781-94. PubMed ID: 8709109
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  • 22. Design and synthesis of novel P2 substituents in diol-based HIV protease inhibitors.
    Adrian Meredith J, Wallberg H, Vrang L, Oscarson S, Parkes K, Hallberg A, Samuelsson B.
    Eur J Med Chem; 2010 Jan 05; 45(1):160-70. PubMed ID: 19926360
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  • 23. Combination of non-natural D-amino acid derivatives and allophenylnorstatine-dimethylthioproline scaffold in HIV protease inhibitors have high efficacy in mutant HIV.
    Nakatani S, Hidaka K, Ami E, Nakahara K, Sato A, Nguyen JT, Hamada Y, Hori Y, Ohnishi N, Nagai A, Kimura T, Hayashi Y, Kiso Y.
    J Med Chem; 2008 May 22; 51(10):2992-3004. PubMed ID: 18426195
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  • 25. Structure-based design of novel HIV protease inhibitors: sulfonamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent non-peptidic inhibitors.
    Thaisrivongs S, Janakiraman MN, Chong KT, Tomich PK, Dolak LA, Turner SR, Strohbach JW, Lynn JC, Horng MM, Hinshaw RR, Watenpaugh KD.
    J Med Chem; 1996 Jun 07; 39(12):2400-10. PubMed ID: 8691434
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  • 26. P1-substituted symmetry-based human immunodeficiency virus protease inhibitors with potent antiviral activity against drug-resistant viruses.
    Degoey DA, Grampovnik DJ, Chen HJ, Flosi WJ, Klein LL, Dekhtyar T, Stoll V, Mamo M, Molla A, Kempf DJ.
    J Med Chem; 2011 Oct 27; 54(20):7094-104. PubMed ID: 21899332
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  • 27. Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor.
    Bäckbro K, Löwgren S, Osterlund K, Atepo J, Unge T, Hultén J, Bonham NM, Schaal W, Karlén A, Hallberg A.
    J Med Chem; 1997 Mar 14; 40(6):898-902. PubMed ID: 9083478
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  • 28. An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study.
    Skálová T, Hasek J, Dohnálek J, Petroková H, Buchtelová E, Dusková J, Soucek M, Majer P, Uhlíková T, Konvalinka J.
    J Med Chem; 2003 Apr 24; 46(9):1636-44. PubMed ID: 12699382
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  • 29. Aza-peptide analogs as potent human immunodeficiency virus type-1 protease inhibitors with oral bioavailability.
    Fässler A, Bold G, Capraro HG, Cozens R, Mestan J, Poncioni B, Rösel J, Tintelnot-Blomley M, Lang M.
    J Med Chem; 1996 Aug 02; 39(16):3203-16. PubMed ID: 8759643
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  • 30. Reduction of peptide character of HIV protease inhibitors that exhibit nanomolar potency against multidrug resistant HIV-1 strains.
    Tamamura H, Koh Y, Ueda S, Sasaki Y, Yamasaki T, Aoki M, Maeda K, Watai Y, Arikuni H, Otaka A, Mitsuya H, Fujii N.
    J Med Chem; 2003 Apr 24; 46(9):1764-8. PubMed ID: 12699395
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  • 34. Stereocontrolled synthesis and biological activity of two diastereoisomers of the potent HIV-1 protease inhibitor saquinavir.
    Righi G, Ciambrone S, Bonini C, Campaner P.
    Bioorg Med Chem; 2008 Jan 15; 16(2):902-8. PubMed ID: 17964171
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  • 35. Lysine derivatives as potent HIV protease inhibitors. Discovery, synthesis and structure-activity relationship studies.
    Bouzide A, Sauvé G, Yelle J.
    Bioorg Med Chem Lett; 2005 Mar 01; 15(5):1509-13. PubMed ID: 15713418
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  • 38. A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease.
    Vega S, Kang LW, Velazquez-Campoy A, Kiso Y, Amzel LM, Freire E.
    Proteins; 2004 May 15; 55(3):594-602. PubMed ID: 15103623
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