These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

177 related items for PubMed ID: 19966032

  • 1. Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes.
    Stewart ML, Burchmore RJ, Clucas C, Hertz-Fowler C, Brooks K, Tait A, Macleod A, Turner CM, De Koning HP, Wong PE, Barrett MP.
    Eukaryot Cell; 2010 Feb; 9(2):336-43. PubMed ID: 19966032
    [Abstract] [Full Text] [Related]

  • 2. The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes.
    Teka IA, Kazibwe AJ, El-Sabbagh N, Al-Salabi MI, Ward CP, Eze AA, Munday JC, Mäser P, Matovu E, Barrett MP, de Koning HP.
    Mol Pharmacol; 2011 Jul; 80(1):110-6. PubMed ID: 21436312
    [Abstract] [Full Text] [Related]

  • 3. Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
    Matovu E, Stewart ML, Geiser F, Brun R, Mäser P, Wallace LJ, Burchmore RJ, Enyaru JC, Barrett MP, Kaminsky R, Seebeck T, de Koning HP.
    Eukaryot Cell; 2003 Oct; 2(5):1003-8. PubMed ID: 14555482
    [Abstract] [Full Text] [Related]

  • 4. Functional analysis of drug resistance-associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein.
    Munday JC, Tagoe DN, Eze AA, Krezdorn JA, Rojas López KE, Alkhaldi AA, McDonald F, Still J, Alzahrani KJ, Settimo L, De Koning HP.
    Mol Microbiol; 2015 May; 96(4):887-900. PubMed ID: 25708978
    [Abstract] [Full Text] [Related]

  • 5. RNA-interference silencing of the adenosine transporter-1 gene in Trypanosoma evansi confers resistance to diminazene aceturate.
    Witola WH, Inoue N, Ohashi K, Onuma M.
    Exp Parasitol; 2004 May; 107(1-2):47-57. PubMed ID: 15208037
    [Abstract] [Full Text] [Related]

  • 6. The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.
    de Koning HP, Anderson LF, Stewart M, Burchmore RJ, Wallace LJ, Barrett MP.
    Antimicrob Agents Chemother; 2004 May; 48(5):1515-9. PubMed ID: 15105099
    [Abstract] [Full Text] [Related]

  • 7. Changes in properties of adenosine transporters in Trypanosoma evansi and modes of selection of resistance to the melaminophenyl arsenical drug, Mel Cy.
    Suswam EA, Taylor DW, Ross CA, Martin RJ.
    Vet Parasitol; 2001 Dec 13; 102(3):193-208. PubMed ID: 11777599
    [Abstract] [Full Text] [Related]

  • 8. Combined contribution of TbAT1 and TbMRPA to drug resistance in Trypanosoma brucei.
    Lüscher A, Nerima B, Mäser P.
    Mol Biochem Parasitol; 2006 Dec 13; 150(2):364-6. PubMed ID: 16935360
    [No Abstract] [Full Text] [Related]

  • 9. Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in African trypanosomes.
    Bridges DJ, Gould MK, Nerima B, Mäser P, Burchmore RJ, de Koning HP.
    Mol Pharmacol; 2007 Apr 13; 71(4):1098-108. PubMed ID: 17234896
    [Abstract] [Full Text] [Related]

  • 10. A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity.
    Barrett MP, Zhang ZQ, Denise H, Giroud C, Baltz T.
    Mol Biochem Parasitol; 1995 Jul 13; 73(1-2):223-9. PubMed ID: 8577330
    [Abstract] [Full Text] [Related]

  • 11. Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
    Scott AG, Tait A, Turner CM.
    Exp Parasitol; 1997 Jul 13; 86(3):181-90. PubMed ID: 9225768
    [Abstract] [Full Text] [Related]

  • 12. Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol.
    Graf FE, Ludin P, Wenzler T, Kaiser M, Brun R, Pyana PP, Büscher P, de Koning HP, Horn D, Mäser P.
    PLoS Negl Trop Dis; 2013 Jul 13; 7(10):e2475. PubMed ID: 24130910
    [Abstract] [Full Text] [Related]

  • 13. Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptake.
    Munday JC, Rojas López KE, Eze AA, Delespaux V, Van Den Abbeele J, Rowan T, Barrett MP, Morrison LJ, de Koning HP.
    Int J Parasitol Drugs Drug Resist; 2013 Dec 13; 3():69-76. PubMed ID: 24533295
    [Abstract] [Full Text] [Related]

  • 14. Genetic variants of the TbAT1 adenosine transporter from African trypanosomes in relapse infections following melarsoprol therapy.
    Matovu E, Geiser F, Schneider V, Mäser P, Enyaru JC, Kaminsky R, Gallati S, Seebeck T.
    Mol Biochem Parasitol; 2001 Sep 28; 117(1):73-81. PubMed ID: 11551633
    [Abstract] [Full Text] [Related]

  • 15. A nucleoside transporter from Trypanosoma brucei involved in drug resistance.
    Mäser P, Sütterlin C, Kralli A, Kaminsky R.
    Science; 1999 Jul 09; 285(5425):242-4. PubMed ID: 10398598
    [Abstract] [Full Text] [Related]

  • 16. Roles for the Trypanosoma brucei P2 transporter in DB75 uptake and resistance.
    Lanteri CA, Stewart ML, Brock JM, Alibu VP, Meshnick SR, Tidwell RR, Barrett MP.
    Mol Pharmacol; 2006 Nov 09; 70(5):1585-92. PubMed ID: 16912218
    [Abstract] [Full Text] [Related]

  • 17. Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.
    Munday JC, Eze AA, Baker N, Glover L, Clucas C, Aguinaga Andrés D, Natto MJ, Teka IA, McDonald J, Lee RS, Graf FE, Ludin P, Burchmore RJ, Turner CM, Tait A, MacLeod A, Mäser P, Barrett MP, Horn D, De Koning HP.
    J Antimicrob Chemother; 2014 Mar 09; 69(3):651-63. PubMed ID: 24235095
    [Abstract] [Full Text] [Related]

  • 18. Genital lesions in male red fronted gazelles (Gazella rufifrons) experimentally infected with Trypanosoma brucei and the effect of melarsamine hydrochloride (Cymelarsan®) and diminazene aceturate (Berenil®) in its treatment.
    Mbaya AW, Nwosu CO, Kumshe HA.
    Theriogenology; 2011 Sep 01; 76(4):721-8. PubMed ID: 21601916
    [Abstract] [Full Text] [Related]

  • 19. Reduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F1Fo-ATPase.
    Eze AA, Gould MK, Munday JC, Tagoe DN, Stelmanis V, Schnaufer A, De Koning HP.
    PLoS Negl Trop Dis; 2016 Aug 01; 10(8):e0004791. PubMed ID: 27518185
    [Abstract] [Full Text] [Related]

  • 20. Differences in Transporters Rather than Drug Targets Are the Principal Determinants of the Different Innate Sensitivities of Trypanosoma congolense and Trypanozoon Subgenus Trypanosomes to Diamidines and Melaminophenyl Arsenicals.
    Ungogo MA, Campagnaro GD, Alghamdi AH, Natto MJ, de Koning HP.
    Int J Mol Sci; 2022 Mar 05; 23(5):. PubMed ID: 35269985
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 9.