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398 related items for PubMed ID: 19966865

  • 1. Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients.
    Kohler EM, Brauburger K, Behrens J, Schneikert J.
    Oncogene; 2010 Mar 18; 29(11):1663-71. PubMed ID: 19966865
    [Abstract] [Full Text] [Related]

  • 2. Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours.
    Kohler EM, Chandra SH, Behrens J, Schneikert J.
    Hum Mol Genet; 2009 Jan 15; 18(2):213-26. PubMed ID: 18854359
    [Abstract] [Full Text] [Related]

  • 3. Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours.
    Kohler EM, Derungs A, Daum G, Behrens J, Schneikert J.
    Hum Mol Genet; 2008 Jul 01; 17(13):1978-87. PubMed ID: 18387968
    [Abstract] [Full Text] [Related]

  • 4. APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerization of truncated APC.
    Schneikert J, Brauburger K, Behrens J.
    Hum Mol Genet; 2011 Sep 15; 20(18):3554-64. PubMed ID: 21665989
    [Abstract] [Full Text] [Related]

  • 5. Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients.
    Crabtree M, Sieber OM, Lipton L, Hodgson SV, Lamlum H, Thomas HJ, Neale K, Phillips RK, Heinimann K, Tomlinson IP.
    Oncogene; 2003 Jul 03; 22(27):4257-65. PubMed ID: 12833148
    [Abstract] [Full Text] [Related]

  • 6. APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'.
    Latchford A, Volikos E, Johnson V, Rogers P, Suraweera N, Tomlinson I, Phillips R, Silver A.
    Hum Mol Genet; 2007 Jan 01; 16(1):78-82. PubMed ID: 17135276
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  • 9. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
    Friedrich A, Kullmann F.
    Med Klin (Munich); 2003 Dec 15; 98(12):776-82. PubMed ID: 14685680
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  • 10. Germline APC mutation on the beta-catenin binding site is associated with a decreased apoptotic level in colorectal adenomas.
    Venesio T, Balsamo A, Scordamaglia A, Bertolaso M, Arrigoni A, Sprujevnik T, Rossini FP, Risio M.
    Mod Pathol; 2003 Jan 15; 16(1):57-65. PubMed ID: 12527714
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  • 13. Functional characterization of the novel APC N1026S variant associated with attenuated familial adenomatous polyposis.
    Menéndez M, González S, Obrador-Hevia A, Domínguez A, Pujol MJ, Valls J, Canela N, Blanco I, Torres A, Pineda-Lucena A, Moreno V, Bachs O, Capellá G.
    Gastroenterology; 2008 Jan 15; 134(1):56-64. PubMed ID: 18166348
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  • 14. Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli.
    Bläker H, Sutter C, Kadmon M, Otto HF, Von Knebel-Doeberitz M, Gebert J, Helmke BM.
    Genes Chromosomes Cancer; 2004 Oct 15; 41(2):93-8. PubMed ID: 15287021
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  • 15. The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin.
    Liu J, Xing Y, Hinds TR, Zheng J, Xu W.
    J Mol Biol; 2006 Jun 30; 360(1):133-44. PubMed ID: 16753179
    [Abstract] [Full Text] [Related]

  • 16. Subcellular localization of beta-catenin and APC proteins in colorectal preneoplastic and neoplastic lesions.
    Sena P, Saviano M, Monni S, Losi L, Roncucci L, Marzona L, De Pol A.
    Cancer Lett; 2006 Sep 28; 241(2):203-12. PubMed ID: 16298038
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  • 17. Recruitment of adenomatous polyposis coli and beta-catenin to axin-puncta.
    Faux MC, Coates JL, Catimel B, Cody S, Clayton AH, Layton MJ, Burgess AW.
    Oncogene; 2008 Oct 02; 27(44):5808-20. PubMed ID: 18591934
    [Abstract] [Full Text] [Related]

  • 18. A beta-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence of beta-catenin germline mutations in FAP patients.
    Müller O, Nimmrich I, Finke U, Friedl W, Hoffmann I.
    Genes Chromosomes Cancer; 1998 May 02; 22(1):37-41. PubMed ID: 9591632
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  • 19. Hot spots in beta-catenin for interactions with LEF-1, conductin and APC.
    von Kries JP, Winbeck G, Asbrand C, Schwarz-Romond T, Sochnikova N, Dell'Oro A, Behrens J, Birchmeier W.
    Nat Struct Biol; 2000 Sep 02; 7(9):800-7. PubMed ID: 10966653
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  • 20. Colorectal cancer and genetic alterations in the Wnt pathway.
    Segditsas S, Tomlinson I.
    Oncogene; 2006 Dec 04; 25(57):7531-7. PubMed ID: 17143297
    [Abstract] [Full Text] [Related]

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