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277 related items for PubMed ID: 20007544

  • 1. Cbfb/Runx1 repression-independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11.
    Hyde RK, Kamikubo Y, Anderson S, Kirby M, Alemu L, Zhao L, Liu PP.
    Blood; 2010 Feb 18; 115(7):1433-43. PubMed ID: 20007544
    [Abstract] [Full Text] [Related]

  • 2. Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice.
    Saida S, Zhen T, Kim E, Yu K, Lopez G, McReynolds LJ, Liu PP.
    Leukemia; 2020 Mar 18; 34(3):759-770. PubMed ID: 31624376
    [Abstract] [Full Text] [Related]

  • 3. RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development.
    Zhen T, Cao Y, Ren G, Zhao L, Hyde RK, Lopez G, Feng D, Alemu L, Zhao K, Liu PP.
    Blood; 2020 Nov 19; 136(21):2373-2385. PubMed ID: 32929473
    [Abstract] [Full Text] [Related]

  • 4. Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice.
    Hyde RK, Zhao L, Alemu L, Liu PP.
    Leukemia; 2015 Aug 19; 29(8):1771-8. PubMed ID: 25742748
    [Abstract] [Full Text] [Related]

  • 5. IL1RL1 is dynamically expressed on Cbfb-MYH11+ leukemia stem cells and promotes cell survival.
    Wang Y, Richter L, Becker M, Amador C, Hyde RK.
    Sci Rep; 2019 Feb 11; 9(1):1729. PubMed ID: 30742053
    [Abstract] [Full Text] [Related]

  • 6. Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11.
    Zhen T, Kwon EM, Zhao L, Hsu J, Hyde RK, Lu Y, Alemu L, Speck NA, Liu PP.
    Blood; 2017 Nov 30; 130(22):2431-2442. PubMed ID: 29018080
    [Abstract] [Full Text] [Related]

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  • 8. Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia-initiating CBFB::MYH11 oncofusion protein.
    Day RB, Hickman JA, Xu Z, Katerndahl CD, Ferraro F, Ramakrishnan SM, Erdmann-Gilmore P, Sprung RW, Mi Y, Townsend RR, Miller CA, Ley TJ.
    J Clin Invest; 2023 Dec 07; 134(4):. PubMed ID: 38061017
    [Abstract] [Full Text] [Related]

  • 9. RUNX1 repression-independent mechanisms of leukemogenesis by fusion genes CBFB-MYH11 and AML1-ETO (RUNX1-RUNX1T1).
    Hyde RK, Liu PP.
    J Cell Biochem; 2010 Aug 01; 110(5):1039-45. PubMed ID: 20589720
    [Abstract] [Full Text] [Related]

  • 10. Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11.
    Kundu M, Chen A, Anderson S, Kirby M, Xu L, Castilla LH, Bodine D, Liu PP.
    Blood; 2002 Oct 01; 100(7):2449-56. PubMed ID: 12239155
    [Abstract] [Full Text] [Related]

  • 11. Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11.
    Castilla LH, Wijmenga C, Wang Q, Stacy T, Speck NA, Eckhaus M, Marín-Padilla M, Collins FS, Wynshaw-Boris A, Liu PP.
    Cell; 1996 Nov 15; 87(4):687-96. PubMed ID: 8929537
    [Abstract] [Full Text] [Related]

  • 12. CBFB-MYH11/RUNX1 together with a compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupies self-renewal genes in inv(16) acute myeloid leukemia.
    Mandoli A, Singh AA, Jansen PW, Wierenga AT, Riahi H, Franci G, Prange K, Saeed S, Vellenga E, Vermeulen M, Stunnenberg HG, Martens JH.
    Leukemia; 2014 Apr 15; 28(4):770-8. PubMed ID: 24002588
    [Abstract] [Full Text] [Related]

  • 13. Strikingly different molecular relapse kinetics in NPM1c, PML-RARA, RUNX1-RUNX1T1, and CBFB-MYH11 acute myeloid leukemias.
    Ommen HB, Schnittger S, Jovanovic JV, Ommen IB, Hasle H, Østergaard M, Grimwade D, Hokland P.
    Blood; 2010 Jan 14; 115(2):198-205. PubMed ID: 19901261
    [Abstract] [Full Text] [Related]

  • 14. Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells.
    Miller JD, Stacy T, Liu PP, Speck NA.
    Blood; 2001 Apr 15; 97(8):2248-56. PubMed ID: 11290585
    [Abstract] [Full Text] [Related]

  • 15. AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis.
    Singh AA, Mandoli A, Prange KH, Laakso M, Martens JH.
    Oncotarget; 2017 Feb 21; 8(8):12855-12865. PubMed ID: 28030795
    [Abstract] [Full Text] [Related]

  • 16. Truncated RUNX1 Generated by the Fusion of RUNX1 to Antisense GRIK2 via a Cryptic Chromosome Translocation Enhances Sensitivity to Granulocyte Colony-Stimulating Factor.
    Abe A, Yamamoto Y, Katsumi A, Yamamoto H, Okamoto A, Inaguma Y, Iriyama C, Tokuda M, Okamoto M, Emi N, Tomita A.
    Cytogenet Genome Res; 2020 Feb 21; 160(5):255-263. PubMed ID: 32544910
    [Abstract] [Full Text] [Related]

  • 17. Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal.
    Zhao X, Chen A, Yan X, Zhang Y, He F, Hayashi Y, Dong Y, Rao Y, Li B, Conway RM, Maiques-Diaz A, Elf SE, Huang N, Zuber J, Xiao Z, Tse W, Tenen DG, Wang Q, Chen W, Mulloy JC, Nimer SD, Huang G.
    Blood; 2014 Mar 13; 123(11):1729-38. PubMed ID: 24449215
    [Abstract] [Full Text] [Related]

  • 18. Function of the inv(16) fusion gene CBFB-MYH11.
    Kundu M, Liu PP.
    Curr Opin Hematol; 2001 Jul 13; 8(4):201-5. PubMed ID: 11561156
    [Abstract] [Full Text] [Related]

  • 19. Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells.
    Morita K, Noura M, Tokushige C, Maeda S, Kiyose H, Kashiwazaki G, Taniguchi J, Bando T, Yoshida K, Ozaki T, Matsuo H, Ogawa S, Liu PP, Nakahata T, Sugiyama H, Adachi S, Kamikubo Y.
    Sci Rep; 2017 Nov 30; 7(1):16604. PubMed ID: 29192243
    [Abstract] [Full Text] [Related]

  • 20. Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MHY11.
    Shigesada K, van de Sluis B, Liu PP.
    Oncogene; 2004 May 24; 23(24):4297-307. PubMed ID: 15156186
    [Abstract] [Full Text] [Related]

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