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Journal Abstract Search

115 related items for PubMed ID: 20008956

  • 1. Identifying a resistance determinant for the antimitotic natural products disorazole C1 and A1.
    Lazo JS, Reese CE, Vogt A, Vollmer LL, Kitchens CA, Günther E, Graham TH, Hopkins CD, Wipf P.
    J Pharmacol Exp Ther; 2010 Mar; 332(3):906-11. PubMed ID: 20008956
    [Abstract] [Full Text] [Related]

  • 2. Microtubule binding and disruption and induction of premature senescence by disorazole C(1).
    Tierno MB, Kitchens CA, Petrik B, Graham TH, Wipf P, Xu FL, Saunders WS, Raccor BS, Balachandran R, Day BW, Stout JR, Walczak CE, Ducruet AP, Reese CE, Lazo JS.
    J Pharmacol Exp Ther; 2009 Mar; 328(3):715-22. PubMed ID: 19066338
    [Abstract] [Full Text] [Related]

  • 3. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.
    Wu S, Guo Z, Hopkins CD, Wei N, Chu E, Wipf P, Schmitz JC.
    Oncotarget; 2015 Dec 01; 6(38):40866-79. PubMed ID: 26506423
    [Abstract] [Full Text] [Related]

  • 4. Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides.
    Hopkins CD, Wipf P.
    Nat Prod Rep; 2009 May 01; 26(5):585-601. PubMed ID: 19387496
    [Abstract] [Full Text] [Related]

  • 5. The Disorazole Z Family of Highly Potent Anticancer Natural Products from Sorangium cellulosum: Structure, Bioactivity, Biosynthesis, and Heterologous Expression.
    Gao Y, Birkelbach J, Fu C, Herrmann J, Irschik H, Morgenstern B, Hirschfelder K, Li R, Zhang Y, Jansen R, Müller R.
    Microbiol Spectr; 2023 Aug 17; 11(4):e0073023. PubMed ID: 37318329
    [Abstract] [Full Text] [Related]

  • 6. Reversal effect of FW-04-806, a macrolide dilactone compound, on multidrug resistance mediated by ABCB1 and ABCG2 in vitro and in vivo.
    Zhang Z, Ma C, Li P, Wu M, Ye S, Fu L, Xu J.
    Cell Commun Signal; 2019 Sep 01; 17(1):110. PubMed ID: 31472682
    [Abstract] [Full Text] [Related]

  • 7. Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.
    Dai CL, Tiwari AK, Wu CP, Su XD, Wang SR, Liu DG, Ashby CR, Huang Y, Robey RW, Liang YJ, Chen LM, Shi CJ, Ambudkar SV, Chen ZS, Fu LW.
    Cancer Res; 2008 Oct 01; 68(19):7905-14. PubMed ID: 18829547
    [Abstract] [Full Text] [Related]

  • 8. Cytotoxic effects of 27 anticancer drugs in HeLa and MDR1-overexpressing derivative cell lines.
    Takara K, Sakaeda T, Yagami T, Kobayashi H, Ohmoto N, Horinouchi M, Nishiguchi K, Okumura K.
    Biol Pharm Bull; 2002 Jun 01; 25(6):771-8. PubMed ID: 12081145
    [Abstract] [Full Text] [Related]

  • 9. Discovery and development of the epothilones : a novel class of antineoplastic drugs.
    Reichenbach H, Höfle G.
    Drugs R D; 2008 Jun 01; 9(1):1-10. PubMed ID: 18095749
    [Abstract] [Full Text] [Related]

  • 10. Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin.
    Loganzo F, Hari M, Annable T, Tan X, Morilla DB, Musto S, Zask A, Kaplan J, Minnick AA, May MK, Ayral-Kaloustian S, Poruchynsky MS, Fojo T, Greenberger LM.
    Mol Cancer Ther; 2004 Oct 01; 3(10):1319-27. PubMed ID: 15486199
    [Abstract] [Full Text] [Related]

  • 11. Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library.
    Zhao L, Pan Y, Gang Y, Wang H, Jin H, Tie J, Xia L, Zhang Y, He L, Yao L, Qiao T, Li T, Liu Z, Fan D.
    J Biol Chem; 2009 Sep 25; 284(39):26273-85. PubMed ID: 19638344
    [Abstract] [Full Text] [Related]

  • 12. Jadomycins are cytotoxic to ABCB1-, ABCC1-, and ABCG2-overexpressing MCF7 breast cancer cells.
    Issa ME, Hall SR, Dupuis SN, Graham CL, Jakeman DL, Goralski KB.
    Anticancer Drugs; 2014 Mar 25; 25(3):255-69. PubMed ID: 24231527
    [Abstract] [Full Text] [Related]

  • 13. Co-suppression of MDR1 (multidrug resistance 1) and GCS (glucosylceramide synthase) restores sensitivity to multidrug resistance breast cancer cells by RNA interference (RNAi).
    Zhang X, Li J, Qiu Z, Gao P, Wu X, Zhou G.
    Cancer Biol Ther; 2009 Jun 25; 8(12):1117-21. PubMed ID: 19502811
    [Abstract] [Full Text] [Related]

  • 14. Total synthesis of (-)-disorazole C1.
    Wipf P, Graham TH.
    J Am Chem Soc; 2004 Dec 01; 126(47):15346-7. PubMed ID: 15563138
    [Abstract] [Full Text] [Related]

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  • 16. Doxorubicin-resistant variants of human prostate cancer cell lines DU 145, PC-3, PPC-1, and TSU-PR1: characterization of biochemical determinants of antineoplastic drug sensitivity.
    David-Beabes GL, Overman MJ, Petrofski JA, Campbell PA, de Marzo AM, Nelson WG.
    Int J Oncol; 2000 Dec 01; 17(6):1077-86. PubMed ID: 11078791
    [Abstract] [Full Text] [Related]

  • 17. Total synthesis of (-)-CP2-disorazole C1.
    Hopkins CD, Schmitz JC, Chu E, Wipf P.
    Org Lett; 2011 Aug 05; 13(15):4088-91. PubMed ID: 21739942
    [Abstract] [Full Text] [Related]

  • 18. TTFields alone and in combination with chemotherapeutic agents effectively reduce the viability of MDR cell sub-lines that over-express ABC transporters.
    Schneiderman RS, Shmueli E, Kirson ED, Palti Y.
    BMC Cancer; 2010 May 23; 10():229. PubMed ID: 20492723
    [Abstract] [Full Text] [Related]

  • 19. Reversing Multidrug Resistance in Chemo-resistant Human Lung Adenocarcinoma (A549/DOX) Cells by Algerian Propolis Through Direct Inhibiting the P-gp Efflux-pump, G0/G1 Cell Cycle Arrest and Apoptosis Induction.
    Kebsa W, Lahouel M, Rouibah H, Zihlif M, Ahram M, Abu-Irmaileh B, Mustafa E, Al-Ameer HJ, Al Shhab M.
    Anticancer Agents Med Chem; 2018 May 23; 18(9):1330-1337. PubMed ID: 30088453
    [Abstract] [Full Text] [Related]

  • 20. Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules.
    Hari M, Loganzo F, Annable T, Tan X, Musto S, Morilla DB, Nettles JH, Snyder JP, Greenberger LM.
    Mol Cancer Ther; 2006 Feb 23; 5(2):270-8. PubMed ID: 16505100
    [Abstract] [Full Text] [Related]

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