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Journal Abstract Search

214 related items for PubMed ID: 20013349

  • 1. Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation.
    Hong B, Lui VW, Hui EP, Ng MH, Cheng SH, Sung FL, Tsang CM, Tsao SW, Chan AT.
    Invest New Drugs; 2011 Jun; 29(3):401-10. PubMed ID: 20013349
    [Abstract] [Full Text] [Related]

  • 2. Regulation of hypoxia-induced mRNA expressions of HIF-1alpha and osteopontin and in vitro radiosensitization by tirapazamine in human nasopharyngeal carcinoma HNE-1 and CNE-1 cells.
    Xu P, Huang JM, Ren Y, Zha X, Deng BF, Wu JH, Lang JY.
    Chin J Cancer; 2010 Feb; 29(2):126-30. PubMed ID: 20109337
    [Abstract] [Full Text] [Related]

  • 3. Suppression of hypoxia-inducible factor 1α (HIF-1α) by tirapazamine is dependent on eIF2α phosphorylation rather than the mTORC1/4E-BP1 pathway.
    Zhang J, Cao J, Weng Q, Wu R, Yan Y, Jing H, Zhu H, He Q, Yang B.
    PLoS One; 2010 Nov 09; 5(11):e13910. PubMed ID: 21085474
    [Abstract] [Full Text] [Related]

  • 4. Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1.
    Hong B, Lui VW, Hui EP, Lu Y, Leung HS, Wong EY, Cheng SH, Ng MH, Mills GB, Chan AT.
    Biochem Pharmacol; 2010 Mar 15; 79(6):842-52. PubMed ID: 19879857
    [Abstract] [Full Text] [Related]

  • 5. XQ2, a novel TPZ derivative, induced G2/M phase arrest and apoptosis under hypoxia in non-small cell lung cancer cells.
    Lou J, Zhou X, Weng Q, Wang DD, Xia Q, Hu Y, He Q, Yang B, Luo P.
    Biosci Biotechnol Biochem; 2010 Mar 15; 74(6):1181-7. PubMed ID: 20530905
    [Abstract] [Full Text] [Related]

  • 6. Positive regulation of HIF-1A expression by EBV oncoprotein LMP1 in nasopharyngeal carcinoma cells.
    Sung WW, Chu YC, Chen PR, Liao MH, Lee JW.
    Cancer Lett; 2016 Nov 01; 382(1):21-31. PubMed ID: 27567526
    [Abstract] [Full Text] [Related]

  • 7. Activation of sterol regulatory element-binding protein 1 (SREBP1)-mediated lipogenesis by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma.
    Lo AK, Lung RW, Dawson CW, Young LS, Ko CW, Yeung WW, Kang W, To KF, Lo KW.
    J Pathol; 2018 Oct 01; 246(2):180-190. PubMed ID: 29968360
    [Abstract] [Full Text] [Related]

  • 8. YC-1 induces S cell cycle arrest and apoptosis by activating checkpoint kinases.
    Yeo EJ, Ryu JH, Chun YS, Cho YS, Jang IJ, Cho H, Kim J, Kim MS, Park JW.
    Cancer Res; 2006 Jun 15; 66(12):6345-52. PubMed ID: 16778212
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of the LKB1-AMPK pathway by the Epstein-Barr virus-encoded LMP1 promotes proliferation and transformation of human nasopharyngeal epithelial cells.
    Lo AK, Lo KW, Ko CW, Young LS, Dawson CW.
    J Pathol; 2013 Jul 15; 230(3):336-46. PubMed ID: 23592276
    [Abstract] [Full Text] [Related]

  • 10. Regulation of DNA Damage Signaling and Cell Death Responses by Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) and LMP2A in Nasopharyngeal Carcinoma Cells.
    Wasil LR, Wei L, Chang C, Lan L, Shair KH.
    J Virol; 2015 Aug 15; 89(15):7612-24. PubMed ID: 25972552
    [Abstract] [Full Text] [Related]

  • 11. K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr virus (EBV)--associated nasopharyngeal carcinoma cells.
    Ng YK, Wong EY, Lau CP, Chan JP, Wong SC, Chan AS, Kwan MP, Tsao SW, Tsang CM, Lai PB, Chan AT, Lui VW.
    Invest New Drugs; 2012 Feb 15; 30(1):48-58. PubMed ID: 20694504
    [Abstract] [Full Text] [Related]

  • 12. Efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in nasopharyngeal carcinoma in vitro and in vivo.
    Huang Y, Tian Y, Zhao Y, Xue C, Zhan J, Liu L, He X, Zhang L.
    Cancer Commun (Lond); 2018 May 03; 38(1):15. PubMed ID: 29764490
    [Abstract] [Full Text] [Related]

  • 13. Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells.
    Lui VW, Lau CP, Ho K, Ng MH, Cheng SH, Tsao SW, Tsang CM, Lei KI, Chan AT, Mok TS.
    Invest New Drugs; 2011 Dec 03; 29(6):1241-52. PubMed ID: 20571878
    [Abstract] [Full Text] [Related]

  • 14. Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells.
    Lo AK, Dawson CW, Young LS, Ko CW, Hau PM, Lo KW.
    J Pathol; 2015 Oct 03; 237(2):238-48. PubMed ID: 26096068
    [Abstract] [Full Text] [Related]

  • 15. Nicotine promotes proliferation of human nasopharyngeal carcinoma cells by regulating α7AChR, ERK, HIF-1α and VEGF/PEDF signaling.
    Shi D, Guo W, Chen W, Fu L, Wang J, Tian Y, Xiao X, Kang T, Huang W, Deng W.
    PLoS One; 2012 Oct 03; 7(8):e43898. PubMed ID: 22952803
    [Abstract] [Full Text] [Related]

  • 16. EBV-encoded LMP-1 sensitizes nasopharyngeal carcinoma cells to genotoxic drugs by down-regulating Cabin1 expression.
    Chang PY, Wu ZZ, Sun NK, Chao CC.
    J Cell Physiol; 2014 Mar 03; 229(3):309-22. PubMed ID: 23939952
    [Abstract] [Full Text] [Related]

  • 17. Activation of lytic cycle of Epstein-Barr virus by suberoylanilide hydroxamic acid leads to apoptosis and tumor growth suppression of nasopharyngeal carcinoma.
    Hui KF, Ho DN, Tsang CM, Middeldorp JM, Tsao GS, Chiang AK.
    Int J Cancer; 2012 Oct 15; 131(8):1930-40. PubMed ID: 22261816
    [Abstract] [Full Text] [Related]

  • 18. Latent membrane protein 1 mediates the resistance of nasopharyngeal carcinoma cells to TRAIL-induced apoptosis by activation of the PI3K/Akt signaling pathway.
    Li SS, Yang S, Wang S, Yang XM, Tang QL, Wang SH.
    Oncol Rep; 2011 Dec 15; 26(6):1573-9. PubMed ID: 21850380
    [Abstract] [Full Text] [Related]

  • 19. Tirapazamine sensitizes hepatocellular carcinoma cells to topoisomerase I inhibitors via cooperative modulation of hypoxia-inducible factor-1α.
    Cai TY, Liu XW, Zhu H, Cao J, Zhang J, Ding L, Lou JS, He QJ, Yang B.
    Mol Cancer Ther; 2014 Mar 15; 13(3):630-42. PubMed ID: 24362462
    [Abstract] [Full Text] [Related]

  • 20. Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.
    Chung GT, Lou WP, Chow C, To KF, Choy KW, Leung AW, Tong CY, Yuen JW, Ko CW, Yip TT, Busson P, Lo KW.
    J Pathol; 2013 Nov 15; 231(3):311-22. PubMed ID: 23868181
    [Abstract] [Full Text] [Related]

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