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Journal Abstract Search

149 related items for PubMed ID: 2002456

  • 1. Synthesis and biological activity of 5-alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic acids.
    Hagen SE, Domagala JM, Heifetz CL, Johnson J.
    J Med Chem; 1991 Mar; 34(3):1155-61. PubMed ID: 2002456
    [Abstract] [Full Text] [Related]

  • 2. Quinolone antibacterials: preparation and activity of bridged bicyclic analogues of the C7-piperazine.
    Kiely JS, Hutt MP, Culbertson TP, Bucsh RA, Worth DF, Lesheski LE, Gogliotti RD, Sesnie JC, Solomon M, Mich TF.
    J Med Chem; 1991 Feb; 34(2):656-63. PubMed ID: 1995890
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological properties of substituted 1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylic acids.
    Miyamoto H, Yamashita H, Ueda H, Tamaoka H, Ohmori K, Nakagawa K.
    Bioorg Med Chem; 1995 Dec; 3(12):1699-706. PubMed ID: 8770395
    [Abstract] [Full Text] [Related]

  • 4. The synthesis and antibacterial activities of quinolones containing five- and six-membered heterocyclic substituents at the 7-position.
    Cooper CS, Klock PL, Chu DT, Fernandes PB.
    J Med Chem; 1990 Apr; 33(4):1246-52. PubMed ID: 2319566
    [Abstract] [Full Text] [Related]

  • 5. Pyridonecarboxylic acids as antibacterial agents. VI. Synthesis and structure-activity relationship of 7-(alkyl, cycloalkyl, and vinyl)-1-cyclopropyl-6-fluoro-4-quinolone-3-carboxylic acids.
    Todo Y, Takagi H, Iino F, Fukuoka Y, Ikeda Y, Tanaka K, Saikawa I, Narita H.
    Chem Pharm Bull (Tokyo); 1994 Oct; 42(10):2049-54. PubMed ID: 7805129
    [Abstract] [Full Text] [Related]

  • 6. Synthesis of possible metabolites of 1-cyclopropyl-1,4-dihydro-6-fluoro-5-methyl-7-(3-methyl-1-piperazinyl)- 4-oxo-3-quinolinecarboxylic acid (Grepafloxacin, OPC-17116).
    Morita S, Otsubo K, Matsubara J, Ohtani T, Kawano Y, Ohmori K, Ohguro K, Uchida M.
    Chem Pharm Bull (Tokyo); 1995 Dec; 43(12):2246-52. PubMed ID: 8582026
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and antibacterial activity of new quinolones containing a 7-[3-(1-amino-1-methylethyl)-1-pyrrolidinyl] moiety. Gram-positive agents with excellent oral activity and low side-effect potential.
    Hagen SE, Domagala JM, Gracheck SJ, Sesnie JA, Stier MA, Suto MJ.
    J Med Chem; 1994 Mar 18; 37(6):733-8. PubMed ID: 8145222
    [Abstract] [Full Text] [Related]

  • 8. Fluoronaphthyridines and quinolones as antibacterial agents. 2. Synthesis and structure-activity relationships of new 1-tert-butyl 7-substituted derivatives.
    Bouzard D, Di Cesare P, Essiz M, Jacquet JP, Kiechel JR, Remuzon P, Weber A, Oki T, Masuyoshi M, Kessler RE.
    J Med Chem; 1990 May 18; 33(5):1344-52. PubMed ID: 2329555
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine.
    McGuirk PR, Jefson MR, Mann DD, Elliott NC, Chang P, Cisek EP, Cornell CP, Gootz TD, Haskell SL, Hindahl MS.
    J Med Chem; 1992 Feb 21; 35(4):611-20. PubMed ID: 1311762
    [Abstract] [Full Text] [Related]

  • 10. Pyridonecarboxylic acids as antibacterial agents. VIII. Synthesis and structure-activity relationship of 7-(1-aminocyclopropyl)-4-oxo-1,8-naphthyridine-3-carboxylic acids and 7-(1-aminocyclopropyl)-4-oxoquinoline-3-carboxylic acids.
    Todo Y, Nitta J, Miyajima M, Fukuoka Y, Yamashiro Y, Nishida N, Saikawa I, Narita H.
    Chem Pharm Bull (Tokyo); 1994 Oct 21; 42(10):2063-70. PubMed ID: 7805131
    [Abstract] [Full Text] [Related]

  • 11. Imidazo- and triazoloquinolones as antibacterial agents. Synthesis and structure-activity relationships.
    Fujita M, Egawa H, Kataoka M, Miyamoto T, Nakano J, Matsumoto J.
    Chem Pharm Bull (Tokyo); 1995 Dec 21; 43(12):2123-32. PubMed ID: 8582014
    [Abstract] [Full Text] [Related]

  • 12. Fluorocyclopropyl quinolones. 1. Synthesis and structure-activity relationships of 1-(2-fluorocyclopropyl)-3-pyridonecarboxylic acid antibacterial agents.
    Atarashi S, Imamura M, Kimura Y, Yoshida A, Hayakawa I.
    J Med Chem; 1993 Oct 29; 36(22):3444-8. PubMed ID: 8230135
    [Abstract] [Full Text] [Related]

  • 13. Fluoronaphthyridines as antibacterial agents. 6. Synthesis and structure-activity relationships of new chiral 7-(1-, 3-, 4-, and 6-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)naphthyridine analogues of 7-[(1R,4R)-2,5- diazabicyclo[2.2.1]heptan-2-yl]-1-(1,1-dimethylethyl)-6-fluoro-1,4-dihy dro-4-oxo-1,8-naphthyridine-3-carboxylic acid. Influence of the configuration on blood pressure in dogs. A quinolone-class effect.
    Remuzon P, Bouzard D, Guiol C, Jacquet JP.
    J Med Chem; 1992 Jul 24; 35(15):2898-909. PubMed ID: 1322990
    [Abstract] [Full Text] [Related]

  • 14. Potent non-6-fluoro-substituted quinolone antibacterials: synthesis and biological activity.
    Ledoussal B, Bouzard D, Coroneos E.
    J Med Chem; 1992 Jan 24; 35(1):198-200. PubMed ID: 1732530
    [No Abstract] [Full Text] [Related]

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  • 16. 6-Aminoquinolones: a new class of quinolone antibacterials?
    Cecchetti V, Clementi S, Cruciani G, Fravolini A, Pagella PG, Savino A, Tabarrini O.
    J Med Chem; 1995 Mar 17; 38(6):973-82. PubMed ID: 7699714
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  • 18. Synthesis and antibacterial activity of thiazolopyrazine-incorporated tetracyclic quinolone antibacterial agents. 2.
    Jinbo Y, Kondo H, Taguchi M, Inoue Y, Sakamoto F, Tsukamoto G.
    J Med Chem; 1994 Aug 19; 37(17):2791-6. PubMed ID: 8064806
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and antibacterial activity of 2-substituted 6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids.
    Jung JC, Baek S, Park OS.
    Farmaco; 2001 Sep 19; 56(9):665-75. PubMed ID: 11680810
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and antibacterial activity of a new series of tetracyclic pyridone carboxylic acids.
    Jinbo Y, Kondo H, Inoue Y, Taguchi M, Tsujishita H, Kotera Y, Sakamoto F, Tsukamoto G.
    J Med Chem; 1993 Sep 03; 36(18):2621-6. PubMed ID: 8410974
    [Abstract] [Full Text] [Related]

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