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Journal Abstract Search

459 related items for PubMed ID: 20039394

  • 1. Evaluation of a dual-wavelength size exclusion HPLC method with improved sensitivity to detect protein aggregates and its use to better characterize degradation pathways of an IgG1 monoclonal antibody.
    Bond MD, Panek ME, Zhang Z, Wang D, Mehndiratta P, Zhao H, Gunton K, Ni A, Nedved ML, Burman S, Volkin DB.
    J Pharm Sci; 2010 Jun; 99(6):2582-97. PubMed ID: 20039394
    [Abstract] [Full Text] [Related]

  • 2. Development of a microflow digital imaging assay to characterize protein particulates during storage of a high concentration IgG1 monoclonal antibody formulation.
    Wuchner K, Büchler J, Spycher R, Dalmonte P, Volkin DB.
    J Pharm Sci; 2010 Aug; 99(8):3343-61. PubMed ID: 20229596
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  • 5. Investigation of degradation processes in IgG1 monoclonal antibodies by limited proteolysis coupled with weak cation-exchange HPLC.
    Lau H, Pace D, Yan B, McGrath T, Smallwood S, Patel K, Park J, Park SS, Latypov RF.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Apr 01; 878(11-12):868-76. PubMed ID: 20206584
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  • 6. Identification and characterization of monoclonal antibody fragments cleaved at the complementarity determining region using orthogonal analytical methods.
    Li W, Yang B, Zhou D, Xu J, Li W, Suen WC.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Mar 24; 1048():121-129. PubMed ID: 28242491
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  • 8. Characterization of Native Reversible Self-Association of a Monoclonal Antibody Mediated by Fab-Fab Interaction.
    Gentiluomo L, Roessner D, Streicher W, Mahapatra S, Harris P, Frieß W.
    J Pharm Sci; 2020 Jan 24; 109(1):443-451. PubMed ID: 31563513
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  • 11. Compatibility, physical stability, and characterization of an IgG4 monoclonal antibody after dilution into different intravenous administration bags.
    Kumru OS, Liu J, Ji JA, Cheng W, Wang YJ, Wang T, Joshi SB, Middaugh CR, Volkin DB.
    J Pharm Sci; 2012 Oct 24; 101(10):3636-50. PubMed ID: 22733600
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  • 12. Correlation between Dynamic Light Scattering and Size Exclusion High Performance Liquid Chromatography for Monitoring the Effect of pH on Stability of Biopharmaceuticals.
    Al-Ghobashy MA, Mostafa MM, Abed HS, Fathalla FA, Salem MY.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Aug 15; 1060():1-9. PubMed ID: 28578190
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  • 13. Quantitation of soluble aggregates by sedimentation velocity analytical ultracentrifugation using an optical alignment system - Aspects of method validation.
    Doyle BL, Rauk AP, Weiss WF, Budyak IL.
    Anal Biochem; 2020 Sep 15; 605():113837. PubMed ID: 32702436
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  • 14. Label-free flow cytometry analysis of subvisible aggregates in liquid IgG1 antibody formulations.
    Nishi H, Mathäs R, Fürst R, Winter G.
    J Pharm Sci; 2014 Jan 15; 103(1):90-9. PubMed ID: 24218205
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  • 16. Nonnative aggregation of an IgG1 antibody in acidic conditions: part 1. Unfolding, colloidal interactions, and formation of high-molecular-weight aggregates.
    Brummitt RK, Nesta DP, Chang L, Chase SF, Laue TM, Roberts CJ.
    J Pharm Sci; 2011 Jun 15; 100(6):2087-103. PubMed ID: 21213308
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  • 17. Induction and analysis of aggregates in a liquid IgG1-antibody formulation.
    Mahler HC, Müller R, Friess W, Delille A, Matheus S.
    Eur J Pharm Biopharm; 2005 Apr 15; 59(3):407-17. PubMed ID: 15760721
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  • 18. Optimized UV detection of high-concentration antibody formulations using high-throughput SE-HPLC.
    Molloy S, Fesinmeyer RM, Martinez T, Piedmonte DM, Pelletier ME, Treuheit MJ, Kleemann GR.
    J Pharm Sci; 2015 Feb 15; 104(2):508-14. PubMed ID: 25392911
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  • 19. Sedimentation velocity analytical ultracentrifugation and SEDFIT/c(s): limits of quantitation for a monoclonal antibody system.
    Gabrielson JP, Randolph TW, Kendrick BS, Stoner MR.
    Anal Biochem; 2007 Feb 01; 361(1):24-30. PubMed ID: 17181992
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  • 20. Detection of protein aggregates by sedimentation velocity analytical ultracentrifugation (SV-AUC): sources of variability and their relative importance.
    Arthur KK, Gabrielson JP, Kendrick BS, Stoner MR.
    J Pharm Sci; 2009 Oct 01; 98(10):3522-39. PubMed ID: 19130472
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