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Journal Abstract Search


770 related items for PubMed ID: 20039427

  • 1. The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.
    Reich N, Maurer B, Akhmetshina A, Venalis P, Dees C, Zerr P, Palumbo K, Zwerina J, Nevskaya T, Gay S, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2010 Jan; 62(1):280-90. PubMed ID: 20039427
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
    Avouac J, Palumbo K, Tomcik M, Zerr P, Dees C, Horn A, Maurer B, Akhmetshina A, Beyer C, Sadowski A, Schneider H, Shiozawa S, Distler O, Schett G, Allanore Y, Distler JH.
    Arthritis Rheum; 2012 May; 64(5):1642-52. PubMed ID: 22139817
    [Abstract] [Full Text] [Related]

  • 3. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta.
    Bhattacharyya S, Ghosh AK, Pannu J, Mori Y, Takagawa S, Chen G, Trojanowska M, Gilliam AC, Varga J.
    Arthritis Rheum; 2005 Apr; 52(4):1248-58. PubMed ID: 15818659
    [Abstract] [Full Text] [Related]

  • 4. Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis.
    Distler JH, Jüngel A, Pileckyte M, Zwerina J, Michel BA, Gay RE, Kowal-Bielecka O, Matucci-Cerinic M, Schett G, Marti HH, Gay S, Distler O.
    Arthritis Rheum; 2007 Dec; 56(12):4203-15. PubMed ID: 18050252
    [Abstract] [Full Text] [Related]

  • 5. Connective tissue growth factor causes persistent proalpha2(I) collagen gene expression induced by transforming growth factor-beta in a mouse fibrosis model.
    Chujo S, Shirasaki F, Kawara S, Inagaki Y, Kinbara T, Inaoki M, Takigawa M, Takehara K.
    J Cell Physiol; 2005 May; 203(2):447-56. PubMed ID: 15605379
    [Abstract] [Full Text] [Related]

  • 6. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis.
    Distler JH, Jüngel A, Huber LC, Schulze-Horsel U, Zwerina J, Gay RE, Michel BA, Hauser T, Schett G, Gay S, Distler O.
    Arthritis Rheum; 2007 Jan; 56(1):311-22. PubMed ID: 17195235
    [Abstract] [Full Text] [Related]

  • 7. Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors.
    Kawaguchi Y, Takagi K, Hara M, Fukasawa C, Sugiura T, Nishimagi E, Harigai M, Kamatani N.
    Arthritis Rheum; 2004 Jan; 50(1):216-26. PubMed ID: 14730619
    [Abstract] [Full Text] [Related]

  • 8. A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis.
    Hasegawa M, Matsushita Y, Horikawa M, Higashi K, Tomigahara Y, Kaneko H, Shirasaki F, Fujimoto M, Takehara K, Sato S.
    Arthritis Rheum; 2009 Nov; 60(11):3465-75. PubMed ID: 19877032
    [Abstract] [Full Text] [Related]

  • 9. Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts.
    Akhmetshina A, Dees C, Pileckyte M, Szucs G, Spriewald BM, Zwerina J, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2008 Aug; 58(8):2553-64. PubMed ID: 18668558
    [Abstract] [Full Text] [Related]

  • 10. MicroRNA-29, a key regulator of collagen expression in systemic sclerosis.
    Maurer B, Stanczyk J, Jüngel A, Akhmetshina A, Trenkmann M, Brock M, Kowal-Bielecka O, Gay RE, Michel BA, Distler JH, Gay S, Distler O.
    Arthritis Rheum; 2010 Jun; 62(6):1733-43. PubMed ID: 20201077
    [Abstract] [Full Text] [Related]

  • 11. CD109 overexpression ameliorates skin fibrosis in a mouse model of bleomycin-induced scleroderma.
    Vorstenbosch J, Al-Ajmi H, Winocour S, Trzeciak A, Lessard L, Philip A.
    Arthritis Rheum; 2013 May; 65(5):1378-83. PubMed ID: 23436317
    [Abstract] [Full Text] [Related]

  • 12. The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.
    Avouac J, Palumbo-Zerr K, Ruzehaji N, Tomcik M, Zerr P, Dees C, Distler A, Beyer C, Schneider H, Distler O, Schett G, Allanore Y, Distler JH.
    Arthritis Rheumatol; 2014 Nov; 66(11):3140-50. PubMed ID: 25155144
    [Abstract] [Full Text] [Related]

  • 13. Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis.
    Yoshizaki A, Yanaba K, Yoshizaki A, Iwata Y, Komura K, Ogawa F, Takenaka M, Shimizu K, Asano Y, Hasegawa M, Fujimoto M, Sato S.
    Arthritis Rheum; 2010 Aug; 62(8):2476-87. PubMed ID: 20506342
    [Abstract] [Full Text] [Related]

  • 14. An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma.
    Pannu J, Gore-Hyer E, Yamanaka M, Smith EA, Rubinchik S, Dong JY, Jablonska S, Blaszczyk M, Trojanowska M.
    Arthritis Rheum; 2004 May; 50(5):1566-77. PubMed ID: 15146427
    [Abstract] [Full Text] [Related]

  • 15. Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis.
    Huber LC, Distler JH, Moritz F, Hemmatazad H, Hauser T, Michel BA, Gay RE, Matucci-Cerinic M, Gay S, Distler O, Jüngel A.
    Arthritis Rheum; 2007 Aug; 56(8):2755-64. PubMed ID: 17665426
    [Abstract] [Full Text] [Related]

  • 16. Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis.
    Maurer B, Busch N, Jüngel A, Pileckyte M, Gay RE, Michel BA, Schett G, Gay S, Distler J, Distler O.
    Circulation; 2009 Dec 08; 120(23):2367-76. PubMed ID: 19933934
    [Abstract] [Full Text] [Related]

  • 17. Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts.
    Mori Y, Ishida W, Bhattacharyya S, Li Y, Platanias LC, Varga J.
    Arthritis Rheum; 2004 Dec 08; 50(12):4008-21. PubMed ID: 15593186
    [Abstract] [Full Text] [Related]

  • 18. Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.
    Pannu J, Gardner H, Shearstone JR, Smith E, Trojanowska M.
    Arthritis Rheum; 2006 Sep 08; 54(9):3011-21. PubMed ID: 16947635
    [Abstract] [Full Text] [Related]

  • 19. Monocyte chemoattractant protein 3 as a mediator of fibrosis: Overexpression in systemic sclerosis and the type 1 tight-skin mouse.
    Ong VH, Evans LA, Shiwen X, Fisher IB, Rajkumar V, Abraham DJ, Black CM, Denton CP.
    Arthritis Rheum; 2003 Jul 08; 48(7):1979-91. PubMed ID: 12847692
    [Abstract] [Full Text] [Related]

  • 20. Src kinases in systemic sclerosis: central roles in fibroblast activation and in skin fibrosis.
    Skhirtladze C, Distler O, Dees C, Akhmetshina A, Busch N, Venalis P, Zwerina J, Spriewald B, Pileckyte M, Schett G, Distler JH.
    Arthritis Rheum; 2008 May 08; 58(5):1475-84. PubMed ID: 18438865
    [Abstract] [Full Text] [Related]


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