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Journal Abstract Search

650 related items for PubMed ID: 20045437

  • 1. Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c.
    Ghavami S, Mutawe MM, Hauff K, Stelmack GL, Schaafsma D, Sharma P, McNeill KD, Hynes TS, Kung SK, Unruh H, Klonisch T, Hatch GM, Los M, Halayko AJ.
    Biochim Biophys Acta; 2010 Apr; 1803(4):452-67. PubMed ID: 20045437
    [Abstract] [Full Text] [Related]

  • 2. Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells.
    Hasenjäger A, Gillissen B, Müller A, Normand G, Hemmati PG, Schuler M, Dörken B, Daniel PT.
    Oncogene; 2004 Jun 03; 23(26):4523-35. PubMed ID: 15064710
    [Abstract] [Full Text] [Related]

  • 3. Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins.
    Ghavami S, Sharma P, Yeganeh B, Ojo OO, Jha A, Mutawe MM, Kashani HH, Los MJ, Klonisch T, Unruh H, Halayko AJ.
    Biochim Biophys Acta; 2014 Jul 03; 1843(7):1259-71. PubMed ID: 24637330
    [Abstract] [Full Text] [Related]

  • 4. Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.
    Lim DY, Park JH.
    Am J Physiol Gastrointest Liver Physiol; 2009 May 03; 296(5):G1060-8. PubMed ID: 19264955
    [Abstract] [Full Text] [Related]

  • 5. Simvastatin induces caspase-dependent apoptosis and activates P53 in OCM-1 cells.
    Wang Y, Xu SL, Wu YZ, Zhao MS, Xu WJ, Yang HY, Li YX.
    Exp Eye Res; 2013 Aug 03; 113():128-34. PubMed ID: 23727160
    [Abstract] [Full Text] [Related]

  • 6. Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53.
    Li J, Lee B, Lee AS.
    J Biol Chem; 2006 Mar 17; 281(11):7260-70. PubMed ID: 16407291
    [Abstract] [Full Text] [Related]

  • 7. Bcl-xL overexpression protects from apoptosis induced by HMG-CoA reductase inhibitors in murine tubular cells.
    Blanco-Colio LM, Justo P, Daehn I, Lorz C, Ortiz A, Egido J.
    Kidney Int; 2003 Jul 17; 64(1):181-91. PubMed ID: 12787408
    [Abstract] [Full Text] [Related]

  • 8. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 9. Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53.
    Ghavami S, Mutawe MM, Sharma P, Yeganeh B, McNeill KD, Klonisch T, Unruh H, Kashani HH, Schaafsma D, Los M, Halayko AJ.
    PLoS One; 2011 Jan 31; 6(1):e16523. PubMed ID: 21304979
    [Abstract] [Full Text] [Related]

  • 10. Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
    Yamaguchi H, Bhalla K, Wang HG.
    Cancer Res; 2003 Apr 01; 63(7):1483-9. PubMed ID: 12670894
    [Abstract] [Full Text] [Related]

  • 11. SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events.
    Yu J, Wang P, Ming L, Wood MA, Zhang L.
    Oncogene; 2007 Jun 21; 26(29):4189-98. PubMed ID: 17237824
    [Abstract] [Full Text] [Related]

  • 12. Activation of p53/p21/PUMA alliance and disruption of PI-3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol from Boswellia serrata.
    Bhushan S, Malik F, Kumar A, Isher HK, Kaur IP, Taneja SC, Singh J.
    Mol Carcinog; 2009 Dec 21; 48(12):1093-108. PubMed ID: 19544329
    [Abstract] [Full Text] [Related]

  • 13. Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis.
    Lee SK, Kim YC, Song SB, Kim YS.
    Biochem Biophys Res Commun; 2010 Jan 22; 391(4):1592-7. PubMed ID: 20043868
    [Abstract] [Full Text] [Related]

  • 14. PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins.
    Li T, Zeng L, Gao W, Cui MZ, Fu X, Xu X.
    Biochim Biophys Acta; 2013 Mar 22; 1832(3):453-74. PubMed ID: 23207240
    [Abstract] [Full Text] [Related]

  • 15. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A, Brady NR.
    J Biol Chem; 2015 Sep 04; 290(36):22005-18. PubMed ID: 26134559
    [Abstract] [Full Text] [Related]

  • 16. Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway.
    Hsieh YC, Rao YK, Wu CC, Huang CY, Geethangili M, Hsu SL, Tzeng YM.
    Chem Res Toxicol; 2010 Jul 19; 23(7):1256-67. PubMed ID: 20557081
    [Abstract] [Full Text] [Related]

  • 17. 3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation.
    Blanco-Colio LM, Villa A, Ortego M, Hernández-Presa MA, Pascual A, Plaza JJ, Egido J.
    Atherosclerosis; 2002 Mar 19; 161(1):17-26. PubMed ID: 11882313
    [Abstract] [Full Text] [Related]

  • 18. Theaflavins target Fas/caspase-8 and Akt/pBad pathways to induce apoptosis in p53-mutated human breast cancer cells.
    Lahiry L, Saha B, Chakraborty J, Adhikary A, Mohanty S, Hossain DM, Banerjee S, Das K, Sa G, Das T.
    Carcinogenesis; 2010 Feb 19; 31(2):259-68. PubMed ID: 19969555
    [Abstract] [Full Text] [Related]

  • 19. The p53 upregulated modulator of apoptosis (PUMA) chemosensitizes intrinsically resistant ovarian cancer cells to cisplatin by lowering the threshold set by Bcl-x(L) and Mcl-1.
    Yuan Z, Cao K, Lin C, Li L, Liu HY, Zhao XY, Liu L, Deng HX, Li J, Nie CL, Wei YQ.
    Mol Med; 2011 Feb 19; 17(11-12):1262-74. PubMed ID: 21863213
    [Abstract] [Full Text] [Related]

  • 20. Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria.
    Lee SK, Kim YS.
    Int J Oncol; 2013 Mar 19; 42(3):810-6. PubMed ID: 23354132
    [Abstract] [Full Text] [Related]

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