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86 related items for PubMed ID: 20049760

  • 1. Glyco-scan: varying glycosylation in the sequence of the peptide hormone PYY3-36 and its effect on receptor selectivity.
    Pedersen SL, Steentoft C, Vrang N, Jensen KJ.
    Chembiochem; 2010 Feb 15; 11(3):366-74. PubMed ID: 20049760
    [Abstract] [Full Text] [Related]

  • 2. Peptide architecture: adding an alpha-helix to the PYY lysine side chain provides nanomolar binding and body-weight-lowering effects.
    Pedersen SL, Sasikumar PG, Vrang N, Jensen KJ.
    ChemMedChem; 2010 Apr 06; 5(4):545-51. PubMed ID: 20183851
    [Abstract] [Full Text] [Related]

  • 3. Modifying the conserved C-terminal tyrosine of the peptide hormone PYY3-36 to improve Y2 receptor selectivity.
    Pedersen SL, Holst B, Vrang N, Jensen KJ.
    J Pept Sci; 2009 Nov 06; 15(11):753-9. PubMed ID: 19739125
    [Abstract] [Full Text] [Related]

  • 4. Peptide hormone isoforms: N-terminally branched PYY3-36 isoforms give improved lipid and fat-cell metabolism in diet-induced obese mice.
    Pedersen SL, Sasikumar PG, Chelur S, Holst B, Artmann A, Jensen KJ, Vrang N.
    J Pept Sci; 2010 Nov 06; 16(11):664-73. PubMed ID: 20853314
    [Abstract] [Full Text] [Related]

  • 5. Structural similarities of micelle-bound peptide YY (PYY) and neuropeptide Y (NPY) are related to their affinity profiles at the Y receptors.
    Lerch M, Mayrhofer M, Zerbe O.
    J Mol Biol; 2004 Jun 18; 339(5):1153-68. PubMed ID: 15178255
    [Abstract] [Full Text] [Related]

  • 6. Improving membrane binding as a design strategy for amphipathic peptide hormones: 2-helix variants of PYY3-36.
    Pedersen SL, Bhatia VK, Jurt S, Paulsson JF, Pedersen MH, Jorgensen R, Holst B, Stamou D, Vrang N, Zerbe O, Jensen KJ.
    J Pept Sci; 2012 Sep 18; 18(9):579-87. PubMed ID: 22865741
    [Abstract] [Full Text] [Related]

  • 7. The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR.
    Nygaard R, Nielbo S, Schwartz TW, Poulsen FM.
    Biochemistry; 2006 Jul 11; 45(27):8350-7. PubMed ID: 16819834
    [Abstract] [Full Text] [Related]

  • 8. Design of Y2 Receptor Selective and Proteolytically Stable PYY3-36 Analogues.
    Østergaard S, Kofoed J, Paulsson JF, Madsen KG, Jorgensen R, Wulff BS.
    J Med Chem; 2018 Dec 13; 61(23):10519-10530. PubMed ID: 30399314
    [Abstract] [Full Text] [Related]

  • 9. A parallel semisynthetic approach for structure-activity relationship studies of peptide YY.
    Albertsen L, Østergaard S, Paulsson JF, Norrild JC, Strømgaard K.
    ChemMedChem; 2013 Sep 13; 8(9):1505-13, 1422. PubMed ID: 23907926
    [Abstract] [Full Text] [Related]

  • 10. Potent and selective tools to investigate neuropeptide Y receptors in the central and peripheral nervous systems: BIB03304 (Y1) and CGP71683A (Y5).
    Dumont Y, Cadieux A, Doods H, Fournier A, Quirion R.
    Can J Physiol Pharmacol; 2000 Feb 13; 78(2):116-25. PubMed ID: 10737674
    [Abstract] [Full Text] [Related]

  • 11. Intravenous peptide YY3-36 and Y2 receptor antagonism in the rat: effects on feeding behaviour.
    Scott V, Kimura N, Stark JA, Luckman SM.
    J Neuroendocrinol; 2005 Jul 13; 17(7):452-7. PubMed ID: 15946163
    [Abstract] [Full Text] [Related]

  • 12. Preferential expression of the neuropeptide Y Y1 over the Y2 receptor subtype in cultured hippocampal neurons and cloning of the rat Y2 receptor.
    St-Pierre JA, Dumont Y, Nouel D, Herzog H, Hamel E, Quirion R.
    Br J Pharmacol; 1998 Jan 13; 123(2):183-94. PubMed ID: 9489605
    [Abstract] [Full Text] [Related]

  • 13. Structure-activity relationships of neuropeptide Y analogues with respect to Y1 and Y2 receptors.
    Beck-Sickinger AG, Jung G.
    Biopolymers; 1995 Jan 13; 37(2):123-42. PubMed ID: 7893945
    [Abstract] [Full Text] [Related]

  • 14. Cloning and characterization of rabbit neuropeptide Y receptor subtypes.
    Umeda T, Kanatani A, Iwaasa H.
    Peptides; 2009 Aug 13; 30(8):1441-7. PubMed ID: 19481128
    [Abstract] [Full Text] [Related]

  • 15. Conformational and biological studies of neuropeptide Y analogs containing structural alterations.
    Fournier A, Gagnon D, Quirion R, Cadieux A, Dumont Y, Pheng LH, St-Pierre S.
    Mol Pharmacol; 1994 Jan 13; 45(1):93-101. PubMed ID: 8302286
    [Abstract] [Full Text] [Related]

  • 16. Molecular characterization of the ligand-receptor interaction of the neuropeptide Y family.
    Cabrele C, Beck-Sickinger AG.
    J Pept Sci; 2000 Mar 13; 6(3):97-122. PubMed ID: 10759209
    [Abstract] [Full Text] [Related]

  • 17. Identification and distribution of mRNA encoding the Y1, Y2, Y4, and Y5 receptors for peptides of the PP-fold family in the rat intestine and colon.
    Goumain M, Voisin T, Lorinet AM, Laburthe M.
    Biochem Biophys Res Commun; 1998 Jun 09; 247(1):52-6. PubMed ID: 9636652
    [Abstract] [Full Text] [Related]

  • 18. Characterization of neuropeptide Y-induced feeding in mice: do Y1-Y6 receptor subtypes mediate feeding?
    Iyengar S, Li DL, Simmons RM.
    J Pharmacol Exp Ther; 1999 May 09; 289(2):1031-40. PubMed ID: 10215684
    [Abstract] [Full Text] [Related]

  • 19. Y5 receptor signalling counteracts the anorectic effects of PYY3-36 in diet-induced obese mice.
    Shi YC, Ip CK, Reed F, Sarruf DA, Wulff BS, Herzog H.
    J Neuroendocrinol; 2017 Oct 09; 29(10):. PubMed ID: 28485050
    [Abstract] [Full Text] [Related]

  • 20. PYY3-36 as an anti-obesity drug target.
    Boggiano MM, Chandler PC, Oswald KD, Rodgers RJ, Blundell JE, Ishii Y, Beattie AH, Holch P, Allison DB, Schindler M, Arndt K, Rudolf K, Mark M, Schoelch C, Joost HG, Klaus S, Thöne-Reineke C, Benoit SC, Seeley RJ, Beck-Sickinger AG, Koglin N, Raun K, Madsen K, Wulff BS, Stidsen CE, Birringer M, Kreuzer OJ, Deng XY, Whitcomb DC, Halem H, Taylor J, Dong J, Datta R, Culler M, Ortmann S, Castañeda TR, Tschöp M.
    Obes Rev; 2005 Nov 09; 6(4):307-22. PubMed ID: 16246216
    [Abstract] [Full Text] [Related]

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