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451 related items for PubMed ID: 20053169

  • 1. Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target.
    Albrecht P, Lewerenz J, Dittmer S, Noack R, Maher P, Methner A.
    CNS Neurol Disord Drug Targets; 2010 Jul; 9(3):373-82. PubMed ID: 20053169
    [Abstract] [Full Text] [Related]

  • 2. Cooperative action of glutamate transporters and cystine/glutamate antiporter system Xc- protects from oxidative glutamate toxicity.
    Lewerenz J, Klein M, Methner A.
    J Neurochem; 2006 Aug; 98(3):916-25. PubMed ID: 16771835
    [Abstract] [Full Text] [Related]

  • 3. Activation of stimulatory heterotrimeric G proteins increases glutathione and protects neuronal cells against oxidative stress.
    Lewerenz J, Letz J, Methner A.
    J Neurochem; 2003 Oct; 87(2):522-31. PubMed ID: 14511129
    [Abstract] [Full Text] [Related]

  • 4. Identification, Expression, and Roles of the Cystine/Glutamate Antiporter in Ocular Tissues.
    Martis RM, Knight LJ, Donaldson PJ, Lim JC.
    Oxid Med Cell Longev; 2020 Oct; 2020():4594606. PubMed ID: 32655769
    [Abstract] [Full Text] [Related]

  • 5. Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro.
    Lewerenz J, Albrecht P, Tien ML, Henke N, Karumbayaram S, Kornblum HI, Wiedau-Pazos M, Schubert D, Maher P, Methner A.
    J Neurochem; 2009 Oct; 111(2):332-43. PubMed ID: 19694903
    [Abstract] [Full Text] [Related]

  • 6. Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum.
    Burdo J, Dargusch R, Schubert D.
    J Histochem Cytochem; 2006 May; 54(5):549-57. PubMed ID: 16399997
    [Abstract] [Full Text] [Related]

  • 7. The oxidative stress-inducible cystine/glutamate antiporter, system x (c) (-) : cystine supplier and beyond.
    Conrad M, Sato H.
    Amino Acids; 2012 Jan; 42(1):231-46. PubMed ID: 21409388
    [Abstract] [Full Text] [Related]

  • 8. Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation.
    Shih AY, Erb H, Sun X, Toda S, Kalivas PW, Murphy TH.
    J Neurosci; 2006 Oct 11; 26(41):10514-23. PubMed ID: 17035536
    [Abstract] [Full Text] [Related]

  • 9. Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling.
    Bridges R, Lutgen V, Lobner D, Baker DA.
    Pharmacol Rev; 2012 Jul 11; 64(3):780-802. PubMed ID: 22759795
    [Abstract] [Full Text] [Related]

  • 10. Oxidative glutamate toxicity can be a component of the excitotoxicity cascade.
    Schubert D, Piasecki D.
    J Neurosci; 2001 Oct 01; 21(19):7455-62. PubMed ID: 11567035
    [Abstract] [Full Text] [Related]

  • 11. beta-N-methylamino-l-alanine induces oxidative stress and glutamate release through action on system Xc(-).
    Liu X, Rush T, Zapata J, Lobner D.
    Exp Neurol; 2009 Jun 01; 217(2):429-33. PubMed ID: 19374900
    [Abstract] [Full Text] [Related]

  • 12. FGF-2 induces neuronal death through upregulation of system xc-.
    Liu X, Albano R, Lobner D.
    Brain Res; 2014 Feb 14; 1547():25-33. PubMed ID: 24374066
    [Abstract] [Full Text] [Related]

  • 13. Cystine/glutamate antiporter blockage induces myelin degeneration.
    Soria FN, Zabala A, Pampliega O, Palomino A, Miguelez C, Ugedo L, Sato H, Matute C, Domercq M.
    Glia; 2016 Aug 14; 64(8):1381-95. PubMed ID: 27247047
    [Abstract] [Full Text] [Related]

  • 14. The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.
    Lewerenz J, Hewett SJ, Huang Y, Lambros M, Gout PW, Kalivas PW, Massie A, Smolders I, Methner A, Pergande M, Smith SB, Ganapathy V, Maher P.
    Antioxid Redox Signal; 2013 Feb 10; 18(5):522-55. PubMed ID: 22667998
    [Abstract] [Full Text] [Related]

  • 15. Distinct nuclear factor-kappaB/Rel proteins have opposing modulatory effects in glutamate-induced cell death in HT22 cells.
    Ishige K, Tanaka M, Arakawa M, Saito H, Ito Y.
    Neurochem Int; 2005 Dec 10; 47(8):545-55. PubMed ID: 16183169
    [Abstract] [Full Text] [Related]

  • 16. Melatonin prevents glutamate-induced oxytosis in the HT22 mouse hippocampal cell line through an antioxidant effect specifically targeting mitochondria.
    Herrera F, Martin V, García-Santos G, Rodriguez-Blanco J, Antolín I, Rodriguez C.
    J Neurochem; 2007 Feb 10; 100(3):736-46. PubMed ID: 17263795
    [Abstract] [Full Text] [Related]

  • 17. Increased expression of cystine/glutamate antiporter in multiple sclerosis.
    Pampliega O, Domercq M, Soria FN, Villoslada P, Rodríguez-Antigüedad A, Matute C.
    J Neuroinflammation; 2011 Jun 03; 8():63. PubMed ID: 21639880
    [Abstract] [Full Text] [Related]

  • 18. High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.
    Thomas AG, Sattler R, Tendyke K, Loiacono KA, Hansen H, Sahni V, Hashizume Y, Rojas C, Slusher BS.
    PLoS One; 2015 Jun 03; 10(8):e0127785. PubMed ID: 26252954
    [Abstract] [Full Text] [Related]

  • 19. Regulation of xCT expression and system x (c) (-) function in neuronal cells.
    Lewerenz J, Maher P, Methner A.
    Amino Acids; 2012 Jan 03; 42(1):171-9. PubMed ID: 21369940
    [Abstract] [Full Text] [Related]

  • 20. Hijacking microglial glutathione by inorganic arsenic impels bystander death of immature neurons through extracellular cystine/glutamate imbalance.
    Singh V, Gera R, Kushwaha R, Sharma AK, Patnaik S, Ghosh D.
    Sci Rep; 2016 Aug 01; 6():30601. PubMed ID: 27477106
    [Abstract] [Full Text] [Related]

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