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234 related items for PubMed ID: 20053498

  • 1. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.
    Li F, Fernandez PP, Rajendran P, Hui KM, Sethi G.
    Cancer Lett; 2010 Jun 28; 292(2):197-207. PubMed ID: 20053498
    [Abstract] [Full Text] [Related]

  • 2. Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.
    Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G.
    J Cell Physiol; 2012 May 28; 227(5):2184-95. PubMed ID: 21792937
    [Abstract] [Full Text] [Related]

  • 3. Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
    Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G.
    J Pharmacol Exp Ther; 2010 Jul 28; 334(1):285-93. PubMed ID: 20378717
    [Abstract] [Full Text] [Related]

  • 4. γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent.
    Rajendran P, Li F, Manu KA, Shanmugam MK, Loo SY, Kumar AP, Sethi G.
    Br J Pharmacol; 2011 May 28; 163(2):283-98. PubMed ID: 21198544
    [Abstract] [Full Text] [Related]

  • 5. Jak inhibitor induces S phase cell-cycle arrest and augments TRAIL-induced apoptosis in human hepatocellular carcinoma cells.
    Fuke H, Shiraki K, Sugimoto K, Tanaka J, Beppu T, Yoneda K, Yamamoto N, Ito K, Masuya M, Takei Y.
    Biochem Biophys Res Commun; 2007 Nov 23; 363(3):738-44. PubMed ID: 17904524
    [Abstract] [Full Text] [Related]

  • 6. Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression.
    Shishodia S, Aggarwal BB.
    Oncogene; 2006 Mar 09; 25(10):1463-73. PubMed ID: 16331273
    [Abstract] [Full Text] [Related]

  • 7. Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway.
    Liao J, Xu T, Zheng JX, Lin JM, Cai QY, Yu DB, Peng J.
    Int J Mol Med; 2013 Jul 09; 32(1):79-84. PubMed ID: 23613111
    [Abstract] [Full Text] [Related]

  • 8. XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells.
    Liu Y, Liu A, Xu Z, Yu W, Wang H, Li C, Lin J.
    Apoptosis; 2011 May 09; 16(5):502-10. PubMed ID: 21311975
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of growth and metastasis of human hepatocellular carcinoma by antisense oligonucleotide targeting signal transducer and activator of transcription 3.
    Li WC, Ye SL, Sun RX, Liu YK, Tang ZY, Kim Y, Karras JG, Zhang H.
    Clin Cancer Res; 2006 Dec 01; 12(23):7140-8. PubMed ID: 17145839
    [Abstract] [Full Text] [Related]

  • 10. β-Caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase.
    Kim C, Cho SK, Kapoor S, Kumar A, Vali S, Abbasi T, Kim SH, Sethi G, Ahn KS.
    Mol Carcinog; 2014 Oct 01; 53(10):793-806. PubMed ID: 23765383
    [Abstract] [Full Text] [Related]

  • 11. Interferon-gamma-induced dephosphorylation of STAT3 and apoptosis are dependent on the mTOR pathway.
    Fang P, Hwa V, Rosenfeld RG.
    Exp Cell Res; 2006 May 01; 312(8):1229-39. PubMed ID: 16427044
    [Abstract] [Full Text] [Related]

  • 12. Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3.
    Subramaniam A, Shanmugam MK, Ong TH, Li F, Perumal E, Chen L, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Hui KM, Sethi G.
    Br J Pharmacol; 2013 Oct 01; 170(4):807-21. PubMed ID: 23848338
    [Abstract] [Full Text] [Related]

  • 13. Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases.
    Lee JH, Chiang SY, Nam D, Chung WS, Lee J, Na YS, Sethi G, Ahn KS.
    Cancer Lett; 2014 Apr 01; 345(1):140-8. PubMed ID: 24333736
    [Abstract] [Full Text] [Related]

  • 14. Blockage of epidermal growth factor receptor by quinazoline tyrosine kinase inhibitors suppresses growth of human hepatocellular carcinoma.
    Liu Y, Poon RT, Shao W, Sun X, Chen H, Kok TW, Fan ST.
    Cancer Lett; 2007 Apr 08; 248(1):32-40. PubMed ID: 16837130
    [Abstract] [Full Text] [Related]

  • 15. A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation.
    Chen KF, Su JC, Liu CY, Huang JW, Chen KC, Chen WL, Tai WT, Shiau CW.
    Cancer Lett; 2012 Aug 01; 321(1):27-35. PubMed ID: 22465052
    [Abstract] [Full Text] [Related]

  • 16. STAT3 & Cytochrome P450 2C9: a novel signaling pathway in liver cancer stem cells.
    Myung SJ, Yoon JH, Yu SJ.
    Biomed Pharmacother; 2012 Dec 01; 66(8):612-6. PubMed ID: 23089473
    [Abstract] [Full Text] [Related]

  • 17. Total alkaloids of Rubus aleaefolius Poir. inhibit the STAT3 signaling pathway leading to suppression of proliferation and cell cycle arrest in a mouse model of hepatocellular carcinoma.
    Zhao J, Lin W, Cao Z, Liu L, Zhuang Q, Zhong X, Hong Z, Peng J.
    Oncol Rep; 2013 Sep 01; 30(3):1309-14. PubMed ID: 23828071
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of Stat3 increases doxorubicin sensitivity in a human metastatic breast cancer cell line.
    Gariboldi MB, Ravizza R, Molteni R, Osella D, Gabano E, Monti E.
    Cancer Lett; 2007 Dec 18; 258(2):181-8. PubMed ID: 17920763
    [Abstract] [Full Text] [Related]

  • 19. Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor kappaB activation.
    Ozaki I, Zhang H, Mizuta T, Ide Y, Eguchi Y, Yasutake T, Sakamaki T, Pestell RG, Yamamoto K.
    Clin Cancer Res; 2007 Apr 01; 13(7):2236-45. PubMed ID: 17404108
    [Abstract] [Full Text] [Related]

  • 20. Morin inhibits STAT3 tyrosine 705 phosphorylation in tumor cells through activation of protein tyrosine phosphatase SHP1.
    Gupta SC, Phromnoi K, Aggarwal BB.
    Biochem Pharmacol; 2013 Apr 01; 85(7):898-912. PubMed ID: 23279849
    [Abstract] [Full Text] [Related]

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