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Journal Abstract Search

204 related items for PubMed ID: 20053781

  • 1. The ATM inhibitor KU-55933 suppresses cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.
    Li Y, Yang DQ.
    Mol Cancer Ther; 2010 Jan; 9(1):113-25. PubMed ID: 20053781
    [Abstract] [Full Text] [Related]

  • 2. Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion.
    Golding SE, Rosenberg E, Valerie N, Hussaini I, Frigerio M, Cockcroft XF, Chong WY, Hummersone M, Rigoreau L, Menear KA, O'Connor MJ, Povirk LF, van Meter T, Valerie K.
    Mol Cancer Ther; 2009 Oct; 8(10):2894-902. PubMed ID: 19808981
    [Abstract] [Full Text] [Related]

  • 3. Ataxia telangiectasia mutated impacts insulin-like growth factor 1 signalling in skeletal muscle.
    Ching JK, Luebbert SH, Collins RL, Zhang Z, Marupudi N, Banerjee S, Hurd RD, Ralston L, Fisher JS.
    Exp Physiol; 2013 Feb; 98(2):526-35. PubMed ID: 22941977
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  • 4. ATM inhibitor KU-55933 induces apoptosis and inhibits motility by blocking GLUT1-mediated glucose uptake in aggressive cancer cells with sustained activation of Akt.
    Harris BRE, Zhang Y, Tao J, Shen R, Zhao X, Cleary MP, Wang T, Yang DQ.
    FASEB J; 2021 Apr; 35(4):e21264. PubMed ID: 33715230
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  • 6. ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.
    Nadkarni A, Shrivastav M, Mladek AC, Schwingler PM, Grogan PT, Chen J, Sarkaria JN.
    J Neurooncol; 2012 Dec; 110(3):349-57. PubMed ID: 23054561
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  • 9. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.
    Hickson I, Zhao Y, Richardson CJ, Green SJ, Martin NM, Orr AI, Reaper PM, Jackson SP, Curtin NJ, Smith GC.
    Cancer Res; 2004 Dec 15; 64(24):9152-9. PubMed ID: 15604286
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  • 10. Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
    Cirstea D, Hideshima T, Rodig S, Santo L, Pozzi S, Vallet S, Ikeda H, Perrone G, Gorgun G, Patel K, Desai N, Sportelli P, Kapoor S, Vali S, Mukherjee S, Munshi NC, Anderson KC, Raje N.
    Mol Cancer Ther; 2010 Apr 15; 9(4):963-75. PubMed ID: 20371718
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  • 12. Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.
    D'Souza AD, Parish IA, McKay SE, Kaech SM, Shadel GS.
    Am J Pathol; 2011 Jun 15; 178(6):2740-51. PubMed ID: 21641396
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  • 13. Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response.
    Golding SE, Rosenberg E, Neill S, Dent P, Povirk LF, Valerie K.
    Cancer Res; 2007 Feb 01; 67(3):1046-53. PubMed ID: 17283137
    [Abstract] [Full Text] [Related]

  • 14. Dynamic inhibition of ATM kinase provides a strategy for glioblastoma multiforme radiosensitization and growth control.
    Golding SE, Rosenberg E, Adams BR, Wignarajah S, Beckta JM, O'Connor MJ, Valerie K.
    Cell Cycle; 2012 Mar 15; 11(6):1167-73. PubMed ID: 22370485
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  • 17. ATM-deficient human fibroblast cells are resistant to low levels of DNA double-strand break induced apoptosis and subsequently undergo drug-induced premature senescence.
    Park J, Jo YH, Cho CH, Choe W, Kang I, Baik HH, Yoon KS.
    Biochem Biophys Res Commun; 2013 Jan 04; 430(1):429-35. PubMed ID: 23178571
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  • 18. Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation.
    Li Y, Wang X, Yue P, Tao H, Ramalingam SS, Owonikoko TK, Deng X, Wang Y, Fu H, Khuri FR, Sun SY.
    J Biol Chem; 2013 May 10; 288(19):13215-24. PubMed ID: 23536185
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  • 19. Phenformin and ataxia-telangiectasia mutated inhibitors synergistically co-suppress liver cancer cell growth by damaging mitochondria.
    Wu T, Zhou S, Qin M, Tang J, Yan X, Huang L, Huang M, Deng J, Xiao D, Hu X, Wu J, Yang X, Li G.
    FEBS Open Bio; 2021 May 10; 11(5):1440-1451. PubMed ID: 33742560
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