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Journal Abstract Search

79 related items for PubMed ID: 20060928

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  • 2. Lipopolysaccharide downregulates the expressions of intestinal pregnane X receptor and cytochrome P450 3a11.
    Xu DX, Wang JP, Sun MF, Chen YH, Wei W.
    Eur J Pharmacol; 2006 Apr 24; 536(1-2):162-70. PubMed ID: 16556443
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  • 3. Down-regulation of pregnane X receptor contributes to cell growth inhibition and apoptosis by anticancer agents in endometrial cancer cells.
    Masuyama H, Nakatsukasa H, Takamoto N, Hiramatsu Y.
    Mol Pharmacol; 2007 Oct 24; 72(4):1045-53. PubMed ID: 17636047
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  • 5. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX, Wei W, Sun MF, Wu CY, Wang JP, Wei LZ, Zhou CF.
    Free Radic Biol Med; 2004 Jul 01; 37(1):10-22. PubMed ID: 15183191
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  • 6. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
    Zhang H, LeCulyse E, Liu L, Hu M, Matoney L, Zhu W, Yan B.
    Arch Biochem Biophys; 1999 Aug 01; 368(1):14-22. PubMed ID: 10415106
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  • 14. Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor.
    Brobst DE, Ding X, Creech KL, Goodwin B, Kelley B, Staudinger JL.
    J Pharmacol Exp Ther; 2004 Aug 01; 310(2):528-35. PubMed ID: 15075359
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  • 16. Serine 350 of human pregnane X receptor is crucial for its heterodimerization with retinoid X receptor alpha and transactivation of target genes in vitro and in vivo.
    Wang YM, Chai SC, Lin W, Chai X, Elias A, Wu J, Ong SS, Pondugula SR, Beard JA, Schuetz EG, Zeng S, Xie W, Chen T.
    Biochem Pharmacol; 2015 Aug 15; 96(4):357-68. PubMed ID: 26119819
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  • 17. The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation.
    Lin YS, Yasuda K, Assem M, Cline C, Barber J, Li CW, Kholodovych V, Ai N, Chen JD, Welsh WJ, Ekins S, Schuetz EG.
    Drug Metab Dispos; 2009 Jun 15; 37(6):1295-304. PubMed ID: 19251824
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  • 18. SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells.
    Tan H, Xu C, Zeng H, Wang Y, Li Y, Fan X, Chen P, Jiang Y, Chen X, Huang M, Bi H.
    J Pharmacol Sci; 2016 Feb 15; 130(2):66-71. PubMed ID: 26782648
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  • 20. Environmental phthalate monoesters activate pregnane X receptor-mediated transcription.
    Hurst CH, Waxman DJ.
    Toxicol Appl Pharmacol; 2004 Sep 15; 199(3):266-74. PubMed ID: 15364542
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