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Journal Abstract Search

129 related items for PubMed ID: 20071170

  • 1. Identification of potent and selective VEGFR receptor tyrosine kinase inhibitors having new amide isostere headgroups.
    Gaudette F, Raeppel S, Nguyen H, Beaulieu N, Beaulieu C, Dupont I, Macleod AR, Besterman JM, Vaisburg A.
    Bioorg Med Chem Lett; 2010 Feb 01; 20(3):848-52. PubMed ID: 20071170
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  • 2. N-(3-fluoro-4-(2-arylthieno[3,2-b]pyridin-7-yloxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: a novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors.
    Raeppel S, Claridge S, Saavedra O, Gaudette F, Zhan L, Mannion M, Zhou N, Raeppel F, Granger MC, Isakovic L, Déziel R, Nguyen H, Beaulieu N, Beaulieu C, Dupont I, Robert MF, Lefebvre S, Dubay M, Rahil J, Wang J, Ste-Croix H, Robert Macleod A, Besterman J, Vaisburg A.
    Bioorg Med Chem Lett; 2009 Mar 01; 19(5):1323-8. PubMed ID: 19211249
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  • 3. Synthesis and biological evaluation of benzamides and benzamidines as selective inhibitors of VEGFR tyrosine kinases.
    Nakamura H, Sasaki Y, Uno M, Yoshikawa T, Asano T, Ban HS, Fukazawa H, Shibuya M, Uehara Y.
    Bioorg Med Chem Lett; 2006 Oct 01; 16(19):5127-31. PubMed ID: 16893647
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  • 5. PTK 787/ZK 222584, a tyrosine kinase inhibitor of all known VEGF receptors, represses tumor growth with high efficacy.
    Hess-Stumpp H, Haberey M, Thierauch KH.
    Chembiochem; 2005 Mar 01; 6(3):550-7. PubMed ID: 15742376
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  • 6. 8-THP-DHI analogs as potent Type I dual TIE-2/VEGF-R2 receptor tyrosine kinase inhibitors.
    Hudkins RL, Zulli AL, Underiner TL, Angeles TS, Aimone LD, Meyer SL, Pauletti D, Chang H, Fedorov EV, Almo SC, Fedorov AA, Ruggeri BA.
    Bioorg Med Chem Lett; 2010 Jun 01; 20(11):3356-60. PubMed ID: 20430619
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  • 7. Discovery of a novel and potent series of dianilinopyrimidineurea and urea isostere inhibitors of VEGFR2 tyrosine kinase.
    Sammond DM, Nailor KE, Veal JM, Nolte RT, Wang L, Knick VB, Rudolph SK, Truesdale AT, Nartey EN, Stafford JA, Kumar R, Cheung M.
    Bioorg Med Chem Lett; 2005 Aug 01; 15(15):3519-23. PubMed ID: 15990302
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  • 8. A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo.
    LaMontagne KR, Butler J, Borowski VB, Fuentes-Pesquera AR, Blevitt JM, Huang S, Li R, Connolly PJ, Greenberger LM.
    Angiogenesis; 2009 Aug 01; 12(3):287-96. PubMed ID: 19544081
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  • 11. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation.
    Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, DiPietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Martin MW, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Wang L, White RD, Whittington DA, Zanon R.
    J Med Chem; 2008 Mar 27; 51(6):1649-67. PubMed ID: 18324761
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  • 12. Application of genomics for identification of systemic toxicity triggers associated with VEGF-R inhibitors.
    Hamadeh HK, Todd M, Healy L, Meyer JT, Kwok AM, Higgins M, Afshari CA.
    Chem Res Toxicol; 2010 Jun 21; 23(6):1025-33. PubMed ID: 20521778
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  • 14. 4-(Azolylphenyl)-phthalazin-1-amines: Novel inhibitors of VEGF receptors I and II.
    Kiselyov AS, Semenov VV, Milligan D.
    Chem Biol Drug Des; 2006 Dec 21; 68(6):308-13. PubMed ID: 17177892
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  • 18. N-(Aryl)-4-(azolylethyl)thiazole-5-carboxamides: novel potent inhibitors of VEGF receptors I and II.
    Kiselyov AS, Piatnitski E, Semenova M, Semenov VV.
    Bioorg Med Chem Lett; 2006 Feb 21; 16(3):602-6. PubMed ID: 16275072
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  • 20. Hetaryl imidazoles: a novel dual inhibitors of VEGF receptors I and II.
    Kiselyov AS, Semenova M, Semenov VV, Piatnitski E, Ouyang S.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1440-4. PubMed ID: 16321531
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