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601 related items for PubMed ID: 20072652

  • 1. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.
    Lin L, Hutzen B, Li PK, Ball S, Zuo M, DeAngelis S, Foust E, Sobo M, Friedman L, Bhasin D, Cen L, Li C, Lin J.
    Neoplasia; 2010 Jan; 12(1):39-50. PubMed ID: 20072652
    [Abstract] [Full Text] [Related]

  • 2. The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells.
    Ball S, Li C, Li PK, Lin J.
    PLoS One; 2011 Apr 19; 6(4):e18820. PubMed ID: 21526200
    [Abstract] [Full Text] [Related]

  • 3. LLL12, a novel small inhibitor targeting STAT3 for hepatocellular carcinoma therapy.
    Zuo M, Li C, Lin J, Javle M.
    Oncotarget; 2015 May 10; 6(13):10940-9. PubMed ID: 25883212
    [Abstract] [Full Text] [Related]

  • 4. XZH-5 inhibits STAT3 phosphorylation and enhances the cytotoxicity of chemotherapeutic drugs in human breast and pancreatic cancer cells.
    Liu A, Liu Y, Jin Z, Hu Q, Lin L, Jou D, Yang J, Xu Z, Wang H, Li C, Lin J.
    PLoS One; 2012 May 10; 7(10):e46624. PubMed ID: 23056374
    [Abstract] [Full Text] [Related]

  • 5. Two small molecule compounds, LLL12 and FLLL32, exhibit potent inhibitory activity on STAT3 in human rhabdomyosarcoma cells.
    Wei CC, Ball S, Lin L, Liu A, Fuchs JR, Li PK, Li C, Lin J.
    Int J Oncol; 2011 Jan 10; 38(1):279-85. PubMed ID: 21109950
    [Abstract] [Full Text] [Related]

  • 6. Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice.
    Onimoe GI, Liu A, Lin L, Wei CC, Schwartz EB, Bhasin D, Li C, Fuchs JR, Li PK, Houghton P, Termuhlen A, Gross T, Lin J.
    Invest New Drugs; 2012 Jun 10; 30(3):916-26. PubMed ID: 21340507
    [Abstract] [Full Text] [Related]

  • 7. A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells.
    Lin L, Benson DM, DeAngelis S, Bakan CE, Li PK, Li C, Lin J.
    Int J Cancer; 2012 Mar 15; 130(6):1459-69. PubMed ID: 21520044
    [Abstract] [Full Text] [Related]

  • 8. Characterization of STAT3 activation and expression in canine and human osteosarcoma.
    Fossey SL, Liao AT, McCleese JK, Bear MD, Lin J, Li PK, Kisseberth WC, London CA.
    BMC Cancer; 2009 Mar 10; 9():81. PubMed ID: 19284568
    [Abstract] [Full Text] [Related]

  • 9. Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines.
    Couto JI, Bear MD, Lin J, Pennel M, Kulp SK, Kisseberth WC, London CA.
    BMC Vet Res; 2012 Dec 17; 8():244. PubMed ID: 23244668
    [Abstract] [Full Text] [Related]

  • 10. Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation.
    Bhutani M, Pathak AK, Nair AS, Kunnumakkara AB, Guha S, Sethi G, Aggarwal BB.
    Clin Cancer Res; 2007 May 15; 13(10):3024-32. PubMed ID: 17505005
    [Abstract] [Full Text] [Related]

  • 11. Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway.
    Ryu K, Susa M, Choy E, Yang C, Hornicek FJ, Mankin HJ, Duan Z.
    BMC Cancer; 2010 May 10; 10():187. PubMed ID: 20459702
    [Abstract] [Full Text] [Related]

  • 12. LLL12 inhibits endogenous and exogenous interleukin-6-induced STAT3 phosphorylation in human pancreatic cancer cells.
    Liu A, Liu Y, Li PK, Li C, Lin J.
    Anticancer Res; 2011 Jun 10; 31(6):2029-35. PubMed ID: 21737619
    [Abstract] [Full Text] [Related]

  • 13. A novel small molecular STAT3 inhibitor, LY5, inhibits cell viability, cell migration, and angiogenesis in medulloblastoma cells.
    Xiao H, Bid HK, Jou D, Wu X, Yu W, Li C, Houghton PJ, Lin J.
    J Biol Chem; 2015 Feb 06; 290(6):3418-29. PubMed ID: 25313399
    [Abstract] [Full Text] [Related]

  • 14. A small molecule STAT3 inhibitor, LLL12, enhances cisplatin‑ and paclitaxel‑mediated inhibition of cell growth and migration in human ovarian cancer cells.
    Zhang R, Chen X, Fu S, Xu L, Lin J.
    Oncol Rep; 2020 Sep 06; 44(3):1224-1232. PubMed ID: 32705214
    [Abstract] [Full Text] [Related]

  • 15. Anti-angiogenic activity of a small molecule STAT3 inhibitor LLL12.
    Bid HK, Oswald D, Li C, London CA, Lin J, Houghton PJ.
    PLoS One; 2012 Sep 06; 7(4):e35513. PubMed ID: 22530037
    [Abstract] [Full Text] [Related]

  • 16. Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells.
    Seo HS, Ku JM, Choi HS, Choi YK, Woo JK, Kim M, Kim I, Na CH, Hur H, Jang BH, Shin YC, Ko SG.
    Oncol Rep; 2016 Jul 06; 36(1):31-42. PubMed ID: 27175602
    [Abstract] [Full Text] [Related]

  • 17. Evaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells.
    Lin L, Hutzen B, Lee HF, Peng Z, Wang W, Zhao C, Lin HJ, Sun D, Li PK, Li C, Korkaya H, Wicha MS, Lin J.
    PLoS One; 2013 Jul 06; 8(12):e82821. PubMed ID: 24376586
    [Abstract] [Full Text] [Related]

  • 18. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
    Park KW, Kundu J, Chae IG, Kim DH, Yu MH, Kundu JK, Chun KS.
    Int J Oncol; 2014 Apr 06; 44(4):1309-15. PubMed ID: 24481553
    [Abstract] [Full Text] [Related]

  • 19. Characterization of STAT3 expression, signaling and inhibition in feline oral squamous cell carcinoma.
    Brown ME, Bear MD, Rosol TJ, Premanandan C, Kisseberth WC, London CA.
    BMC Vet Res; 2015 Aug 14; 11():206. PubMed ID: 26272737
    [Abstract] [Full Text] [Related]

  • 20. JAK2 regulation by licochalcone H inhibits the cell growth and induces apoptosis in oral squamous cell carcinoma.
    Oh HN, Oh KB, Lee MH, Seo JH, Kim E, Yoon G, Cho SS, Cho YS, Choi HW, Chae JI, Shim JH.
    Phytomedicine; 2019 Jan 14; 52():60-69. PubMed ID: 30599913
    [Abstract] [Full Text] [Related]

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