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Journal Abstract Search

179 related items for PubMed ID: 20096721

  • 1.
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  • 2. Time-dependent inactivation of aromatase by 6-alkylandrosta-1,4-diene-3,17-diones. Effects of length and configuration of 6-alkyl group.
    Numazawa M, Oshibe M, Yamaguchi S, Tachibana M.
    J Med Chem; 1996 Mar 01; 39(5):1033-8. PubMed ID: 8676338
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  • 3. Aromatase inactivation by 2-substituted derivatives of the suicide substrate androsta-1,4-diene-3,17-dione.
    Takahashi M, Handa W, Umeta H, Ishikawa S, Yamashita K, Numazawa M.
    J Steroid Biochem Mol Biol; 2009 Sep 01; 116(3-5):191-9. PubMed ID: 19520161
    [Abstract] [Full Text] [Related]

  • 4. Biochemistry and pharmacology of 7alpha-substituted androstenediones as aromatase inhibitors.
    Brueggemeier RW, O'Reilly JM, Lovely CJ, Ward PJ, Quinn AL, Baker D, Darby MV, Gu XJ, Gilbert NE.
    J Steroid Biochem Mol Biol; 1997 Apr 01; 61(3-6):247-54. PubMed ID: 9365197
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  • 5. Synthesis and structure-activity relationships of 6-phenylaliphatic-substituted C19 steroids having a 1,4-diene, 4,6-diene, or 1,4,6-triene structure as aromatase inhibitors.
    Numazawa M, Yamaguchi S.
    Steroids; 1999 Mar 01; 64(3):187-96. PubMed ID: 10400379
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  • 6. Probing the binding pocket of the active site of aromatase with 6-ether or 6-ester substituted androst-4-ene-3,17-diones and their diene and triene analogs.
    Numazawa M, Shelangouski M, Nagasaka M.
    Steroids; 2000 Dec 01; 65(12):871-82. PubMed ID: 11077085
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  • 7. Studies directed towards a mechanistic evaluation of inactivation of aromatase by the suicide substrates androsta-1,4-diene-3,17-diones and its 6-ene derivatives aromatase inactivation by the 19-substituted derivatives and their enzymic aromatization.
    Numazawa M, Nagaoka M, Handa W, Ogawa Y, Matsuoka S.
    J Steroid Biochem Mol Biol; 2007 Dec 01; 107(3-5):211-9. PubMed ID: 17656084
    [Abstract] [Full Text] [Related]

  • 8. 6-Phenylaliphatic-substituted androst-4-ene-3,17-diones as aromatase inhibitors: structure-activity relationships.
    Numazawa M, Yamaguchi S.
    J Steroid Biochem Mol Biol; 1998 Oct 01; 67(1):41-8. PubMed ID: 9780028
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  • 9.
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  • 10. 6-Alkylandrosta-4,6-diene-3,17-diones and their 1,4,6-triene analogs as aromatase inhibitors. Structure-activity relationships.
    Numazawa M, Oshibe M, Yamaguchi S.
    Steroids; 1997 Oct 01; 62(8-9):595-602. PubMed ID: 9292934
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  • 14. Steroidal metabolites transformed by Marchantia polymorpha cultures block breast cancer estrogen biosynthesis.
    Hegazy ME, Gamal-Eldeen AM, El-Halawany AM, Mohamed Ael-H, Paré PW.
    Cell Biochem Biophys; 2012 May 01; 63(1):85-96. PubMed ID: 22350385
    [Abstract] [Full Text] [Related]

  • 15. Probing the active site of aromatase with 2-methyl-substituted androstenedione analogs.
    Numazawa M, Watari Y, Yamada K, Umemura N, Handa W.
    Steroids; 2003 Aug 01; 68(6):503-13. PubMed ID: 12906935
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  • 16. 6 beta-Propynyl-substituted steroids: mechanism-based enzyme-activated irreversible inhibitors of aromatase.
    Akkani A, Paterlini G, Gleason WB, Ojala WH, Abul-Hajj YJ.
    J Med Chem; 1997 Sep 26; 40(20):3263-70. PubMed ID: 9379446
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  • 17.
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  • 18. Enzymic aromatization of 6-alkyl-substituted androgens, potent competitive and mechanism-based inhibitors of aromatase.
    Numazawa M, Yoshimura A, Oshibe M.
    Biochem J; 1998 Jan 01; 329 ( Pt 1)(Pt 1):151-6. PubMed ID: 9405288
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  • 19. Synthesis and aromatase inhibitory activity of some new 16E-arylidenosteroids.
    Bansal R, Thota S, Karkra N, Minu M, Zimmer C, Hartmann RW.
    Bioorg Chem; 2012 Dec 01; 45():36-40. PubMed ID: 23064126
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