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707 related items for PubMed ID: 20105433

  • 1. Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?
    Aurbek N, Herkert NM, Koller M, Thiermann H, Worek F.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):215-9. PubMed ID: 20105433
    [Abstract] [Full Text] [Related]

  • 2. Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase.
    Bartling A, Worek F, Szinicz L, Thiermann H.
    Toxicology; 2007 Apr 20; 233(1-3):166-72. PubMed ID: 16904809
    [Abstract] [Full Text] [Related]

  • 3. Kinetic analysis of reactivation and aging of human acetylcholinesterase inhibited by different phosphoramidates.
    Worek F, Aurbek N, Koller M, Becker C, Eyer P, Thiermann H.
    Biochem Pharmacol; 2007 Jun 01; 73(11):1807-17. PubMed ID: 17382909
    [Abstract] [Full Text] [Related]

  • 4. Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study.
    Worek F, Herkert NM, Koller M, Aurbek N, Thiermann H.
    Toxicol Lett; 2009 Jun 01; 187(2):119-23. PubMed ID: 19429253
    [Abstract] [Full Text] [Related]

  • 5. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
    Maxwell DM, Brecht KM, Sweeney RE.
    Chem Biol Interact; 2013 Mar 25; 203(1):72-6. PubMed ID: 22982773
    [Abstract] [Full Text] [Related]

  • 6. Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis.
    Aurbek N, Thiermann H, Eyer F, Eyer P, Worek F.
    Toxicology; 2009 May 17; 259(3):133-9. PubMed ID: 19428953
    [Abstract] [Full Text] [Related]

  • 7. Reactivation kinetics of a homologous series of bispyridinium bis-oximes with nerve agent-inhibited human acetylcholinesterase.
    Worek F, von der Wellen J, Musilek K, Kuca K, Thiermann H.
    Arch Toxicol; 2012 Sep 17; 86(9):1379-86. PubMed ID: 22437842
    [Abstract] [Full Text] [Related]

  • 8. A comparison of the efficacy of a bispyridinium oxime--1,4-bis-(2-hydroxyiminomethylpyridinium) butane dibromide and currently used oximes to reactivate sarin, tabun or cyclosarin-inhibited acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J.
    Pharmazie; 2004 Oct 17; 59(10):795-8. PubMed ID: 15544060
    [Abstract] [Full Text] [Related]

  • 9. A comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques.
    Bajgar J, Hajek P, Zdarova JK, Kassa J, Paseka A, Slizova D, Krs O, Kuca K, Jun D, Fusek J, Capek L.
    J Enzyme Inhib Med Chem; 2010 Dec 17; 25(6):790-7. PubMed ID: 21054236
    [Abstract] [Full Text] [Related]

  • 10. In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity.
    Calić M, Vrdoljak AL, Radić B, Jelić D, Jun D, Kuca K, Kovarik Z.
    Toxicology; 2006 Feb 15; 219(1-3):85-96. PubMed ID: 16332406
    [Abstract] [Full Text] [Related]

  • 11. Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes.
    Worek F, Thiermann H, Szinicz L, Eyer P.
    Biochem Pharmacol; 2004 Dec 01; 68(11):2237-48. PubMed ID: 15498514
    [Abstract] [Full Text] [Related]

  • 12. An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
    Kassa J, Karasova J, Musilek K, Kuca K.
    Toxicology; 2008 Jan 20; 243(3):311-6. PubMed ID: 18054821
    [Abstract] [Full Text] [Related]

  • 13. Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium.
    Luo C, Saxena A, Smith M, Garcia G, Radić Z, Taylor P, Doctor BP.
    Biochemistry; 1999 Aug 03; 38(31):9937-47. PubMed ID: 10433700
    [Abstract] [Full Text] [Related]

  • 14. Comparison of the oxime-induced reactivation of rhesus monkey, swine and guinea pig erythrocyte acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity.
    Herkert NM, Lallement G, Clarençon D, Thiermann H, Worek F.
    Toxicology; 2009 Apr 28; 258(2-3):79-83. PubMed ID: 19428926
    [Abstract] [Full Text] [Related]

  • 15. Analysis of inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds with human and pig acetylcholinesterase.
    Aurbek N, Thiermann H, Szinicz L, Eyer P, Worek F.
    Toxicology; 2006 Jul 05; 224(1-2):91-9. PubMed ID: 16720069
    [Abstract] [Full Text] [Related]

  • 16. Comparison of in vitro potency of oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited acetylcholinesterase in various parts of pig brain.
    Kuca K, Cabal J, Kassa J, Jun D, Hrabinová M.
    J Appl Toxicol; 2005 Jul 05; 25(4):271-6. PubMed ID: 16021679
    [Abstract] [Full Text] [Related]

  • 17. Comparative study of oxime-induced reactivation of erythrocyte and muscle AChE from different animal species following inhibition by sarin or paraoxon.
    Herkert NM, Aurbek N, Eyer P, Thiermann H, Worek F.
    Toxicol Lett; 2010 May 04; 194(3):94-101. PubMed ID: 20156534
    [Abstract] [Full Text] [Related]

  • 18. Mechanism for potent reactivation ability of H oximes analyzed by reactivation kinetic studies with cholinesterases from different species.
    Luo C, Chambers C, Yang Y, Saxena A.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):185-90. PubMed ID: 20096273
    [Abstract] [Full Text] [Related]

  • 19. Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro.
    Worek F, Aurbek N, Thiermann H.
    J Appl Toxicol; 2007 Sep 06; 27(6):582-8. PubMed ID: 17370251
    [Abstract] [Full Text] [Related]

  • 20. Comparison of human and guinea pig acetylcholinesterase sequences and rates of oxime-assisted reactivation.
    Cadieux CL, Broomfield CA, Kirkpatrick MG, Kazanski ME, Lenz DE, Cerasoli DM.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):229-33. PubMed ID: 20433814
    [Abstract] [Full Text] [Related]

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