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241 related items for PubMed ID: 20106945

  • 1. Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification.
    Jennen DG, Magkoufopoulou C, Ketelslegers HB, van Herwijnen MH, Kleinjans JC, van Delft JH.
    Toxicol Sci; 2010 May; 115(1):66-79. PubMed ID: 20106945
    [Abstract] [Full Text] [Related]

  • 2. Baseline and genotoxic compound induced gene expression profiles in HepG2 and HepaRG compared to primary human hepatocytes.
    Jetten MJ, Kleinjans JC, Claessen SM, Chesné C, van Delft JH.
    Toxicol In Vitro; 2013 Oct; 27(7):2031-40. PubMed ID: 23911569
    [Abstract] [Full Text] [Related]

  • 3. Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.
    Doktorova TY, Yildirimman R, Vinken M, Vilardell M, Vanhaecke T, Gmuender H, Bort R, Brolen G, Holmgren G, Li R, Chesne C, van Delft J, Kleinjans J, Castell J, Bjorquist P, Herwig R, Rogiers V.
    Carcinogenesis; 2013 Jun; 34(6):1393-402. PubMed ID: 23393228
    [Abstract] [Full Text] [Related]

  • 4. Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time.
    Mathijs K, Brauers KJ, Jennen DG, Boorsma A, van Herwijnen MH, Gottschalk RW, Kleinjans JC, van Delft JH.
    Toxicol Sci; 2009 Dec; 112(2):374-84. PubMed ID: 19770486
    [Abstract] [Full Text] [Related]

  • 5. Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells.
    Harris AJ, Dial SL, Casciano DA.
    Mutat Res; 2004 May 18; 549(1-2):79-99. PubMed ID: 15120964
    [Abstract] [Full Text] [Related]

  • 6. Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.
    Doktorova TY, Ellinger-Ziegelbauer H, Vinken M, Vanhaecke T, van Delft J, Kleinjans J, Ahr HJ, Rogiers V.
    Arch Toxicol; 2012 Sep 18; 86(9):1399-411. PubMed ID: 22484513
    [Abstract] [Full Text] [Related]

  • 7. Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: toxicokinetics is essential for in vivo-in vitro comparisons.
    van Kesteren PC, Zwart PE, Schaap MM, Pronk TE, van Herwijnen MH, Kleinjans JC, Bokkers BG, Godschalk RW, Zeilmaker MJ, van Steeg H, Luijten M.
    Arch Toxicol; 2013 Mar 18; 87(3):505-15. PubMed ID: 23052197
    [Abstract] [Full Text] [Related]

  • 8. Toxicogenomics applied to in vitro carcinogenicity testing with Balb/c 3T3 cells revealed a gene signature predictive of chemical carcinogens.
    Rohrbeck A, Salinas G, Maaser K, Linge J, Salovaara S, Corvi R, Borlak J.
    Toxicol Sci; 2010 Nov 18; 118(1):31-41. PubMed ID: 20713471
    [Abstract] [Full Text] [Related]

  • 9. Gene expression profiling in primary mouse hepatocytes discriminates true from false-positive genotoxic compounds.
    Mathijs K, Brauers KJ, Jennen DG, Lizarraga D, Kleinjans JC, van Delft JH.
    Mutagenesis; 2010 Nov 18; 25(6):561-8. PubMed ID: 20650930
    [Abstract] [Full Text] [Related]

  • 10. Dose- and time-dependent effects of phenobarbital on gene expression profiling in human hepatoma HepaRG cells.
    Lambert CB, Spire C, Claude N, Guillouzo A.
    Toxicol Appl Pharmacol; 2009 Feb 01; 234(3):345-60. PubMed ID: 19084549
    [Abstract] [Full Text] [Related]

  • 11. Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.
    van Kesteren PC, Zwart PE, Pennings JL, Gottschalk WH, Kleinjans JC, van Delft JH, van Steeg H, Luijten M.
    Toxicol Sci; 2011 Sep 01; 123(1):123-32. PubMed ID: 21715664
    [Abstract] [Full Text] [Related]

  • 12. Reproducible chemical-induced changes in gene expression profiles in human hepatoma HepaRG cells under various experimental conditions.
    Lambert CB, Spire C, Renaud MP, Claude N, Guillouzo A.
    Toxicol In Vitro; 2009 Apr 01; 23(3):466-75. PubMed ID: 19159669
    [Abstract] [Full Text] [Related]

  • 13. Time series analysis of benzo[A]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets.
    van Delft JH, Mathijs K, Staal YC, van Herwijnen MH, Brauers KJ, Boorsma A, Kleinjans JC.
    Toxicol Sci; 2010 Oct 01; 117(2):381-92. PubMed ID: 20624995
    [Abstract] [Full Text] [Related]

  • 14. Modulation of different stress pathways after styrene and styrene-7,8-oxide exposure in HepG2 cell line and normal human hepatocytes.
    Diodovich C, Urani C, Maurici D, Malerba I, Melchioretto P, Orlandi M, Zoia L, Campi V, Carfi' M, Pellizzer C, Gribaldo L.
    J Appl Toxicol; 2006 Oct 01; 26(4):317-25. PubMed ID: 16705669
    [Abstract] [Full Text] [Related]

  • 15. Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes.
    Rieswijk L, Brauers KJ, Coonen ML, van Breda SG, Jennen DG, Kleinjans JC.
    Mutagenesis; 2015 Nov 01; 30(6):771-84. PubMed ID: 25976910
    [Abstract] [Full Text] [Related]

  • 16. Trovafloxacin-induced gene expression changes in liver-derived in vitro systems: comparison of primary human hepatocytes to HepG2 cells.
    Liguori MJ, Blomme EA, Waring JF.
    Drug Metab Dispos; 2008 Feb 01; 36(2):223-33. PubMed ID: 17967932
    [Abstract] [Full Text] [Related]

  • 17. Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2.
    Hockley SL, Arlt VM, Brewer D, Giddings I, Phillips DH.
    BMC Genomics; 2006 Oct 16; 7():260. PubMed ID: 17042939
    [Abstract] [Full Text] [Related]

  • 18. Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds.
    Josse R, Dumont J, Fautrel A, Robin MA, Guillouzo A.
    Toxicol Appl Pharmacol; 2012 Jan 15; 258(2):176-87. PubMed ID: 22100608
    [Abstract] [Full Text] [Related]

  • 19. NTP toxicology and carcinogenesis studies of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage Studies).
    National Toxicology Program.
    Natl Toxicol Program Tech Rep Ser; 2006 Jan 15; (520):4-246. PubMed ID: 16628245
    [Abstract] [Full Text] [Related]

  • 20. Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling.
    van Delft JH, van Agen E, van Breda SG, Herwijnen MH, Staal YC, Kleinjans JC.
    Mutat Res; 2005 Aug 04; 575(1-2):17-33. PubMed ID: 15924884
    [Abstract] [Full Text] [Related]


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