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199 related items for PubMed ID: 20106974

  • 1. Solution structure of proinsulin: connecting domain flexibility and prohormone processing.
    Yang Y, Hua QX, Liu J, Shimizu EH, Choquette MH, Mackin RB, Weiss MA.
    J Biol Chem; 2010 Mar 12; 285(11):7847-51. PubMed ID: 20106974
    [Abstract] [Full Text] [Related]

  • 2. Deciphering the hidden informational content of protein sequences: foldability of proinsulin hinges on a flexible arm that is dispensable in the mature hormone.
    Liu M, Hua QX, Hu SQ, Jia W, Yang Y, Saith SE, Whittaker J, Arvan P, Weiss MA.
    J Biol Chem; 2010 Oct 01; 285(40):30989-1001. PubMed ID: 20663888
    [Abstract] [Full Text] [Related]

  • 3. Peptide Model of the Mutant Proinsulin Syndrome. II. Nascent Structure and Biological Implications.
    Yang Y, Glidden MD, Dhayalan B, Zaykov AN, Chen YS, Wickramasinghe NP, DiMarchi RD, Weiss MA.
    Front Endocrinol (Lausanne); 2022 Oct 01; 13():821091. PubMed ID: 35299958
    [Abstract] [Full Text] [Related]

  • 4. NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition.
    Weiss MA, Frank BH, Khait I, Pekar A, Heiney R, Shoelson SE, Neuringer LJ.
    Biochemistry; 1990 Sep 11; 29(36):8389-401. PubMed ID: 2252901
    [Abstract] [Full Text] [Related]

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  • 6. Structural analysis of proinsulin hexamer assembly by hydroxyl radical footprinting and computational modeling.
    Kiselar JG, Datt M, Chance MR, Weiss MA.
    J Biol Chem; 2011 Dec 23; 286(51):43710-43716. PubMed ID: 22033917
    [Abstract] [Full Text] [Related]

  • 7. Revisiting Proinsulin Processing: Evidence That Human β-Cells Process Proinsulin With Prohormone Convertase (PC) 1/3 but Not PC2.
    Ramzy A, Asadi A, Kieffer TJ.
    Diabetes; 2020 Jul 23; 69(7):1451-1462. PubMed ID: 32291281
    [Abstract] [Full Text] [Related]

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  • 9. Peptide Model of the Mutant Proinsulin Syndrome. I. Design and Clinical Correlation.
    Dhayalan B, Glidden MD, Zaykov AN, Chen YS, Yang Y, Phillips NB, Ismail-Beigi F, Jarosinski MA, DiMarchi RD, Weiss MA.
    Front Endocrinol (Lausanne); 2022 Jul 23; 13():821069. PubMed ID: 35299972
    [Abstract] [Full Text] [Related]

  • 10. Predicted structural alterations in proinsulin during its interactions with prohormone convertases.
    Lipkind G, Steiner DF.
    Biochemistry; 1999 Jan 19; 38(3):890-6. PubMed ID: 9893983
    [Abstract] [Full Text] [Related]

  • 11. Diabetes mellitus due to the toxic misfolding of proinsulin variants.
    Weiss MA.
    FEBS Lett; 2013 Jun 27; 587(13):1942-50. PubMed ID: 23669362
    [Abstract] [Full Text] [Related]

  • 12. Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.
    Haataja L, Manickam N, Soliman A, Tsai B, Liu M, Arvan P.
    Diabetes; 2016 Apr 27; 65(4):1050-60. PubMed ID: 26822090
    [Abstract] [Full Text] [Related]

  • 13. Proinsulin and the genetics of diabetes mellitus.
    Weiss MA.
    J Biol Chem; 2009 Jul 17; 284(29):19159-63. PubMed ID: 19395706
    [Abstract] [Full Text] [Related]

  • 14. Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.
    Hua QX, Hu SQ, Jia W, Chu YC, Burke GT, Wang SH, Wang RY, Katsoyannis PG, Weiss MA.
    J Mol Biol; 1998 Mar 20; 277(1):103-18. PubMed ID: 9514738
    [Abstract] [Full Text] [Related]

  • 15. Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth.
    Liu M, Hodish I, Haataja L, Lara-Lemus R, Rajpal G, Wright J, Arvan P.
    Trends Endocrinol Metab; 2010 Nov 20; 21(11):652-9. PubMed ID: 20724178
    [Abstract] [Full Text] [Related]

  • 16. The folding nucleus of the insulin superfamily: a flexible peptide model foreshadows the native state.
    Hua QX, Mayer JP, Jia W, Zhang J, Weiss MA.
    J Biol Chem; 2006 Sep 22; 281(38):28131-42. PubMed ID: 16864583
    [Abstract] [Full Text] [Related]

  • 17. Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
    Arunagiri A, Alam M, Haataja L, Draz H, Alasad B, Samy P, Sadique N, Tong Y, Cai Y, Shakeri H, Fantuzzi F, Ibrahim H, Jang I, Sidarala V, Soleimanpour SA, Satin LS, Otonkoski T, Cnop M, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P.
    Protein Sci; 2024 Apr 22; 33(4):e4949. PubMed ID: 38511500
    [Abstract] [Full Text] [Related]

  • 18. Diabetes-Associated Mutations in Proinsulin Provide a "Molecular Rheostat" of Nascent Foldability.
    Dhayalan B, Weiss MA.
    Curr Diab Rep; 2022 Feb 22; 22(2):85-94. PubMed ID: 35119630
    [Abstract] [Full Text] [Related]

  • 19. (Pro)Insulin processing: a historical perspective.
    Davidson HW.
    Cell Biochem Biophys; 2004 Feb 22; 40(3 Suppl):143-58. PubMed ID: 15289650
    [Abstract] [Full Text] [Related]

  • 20. Islet prohormone processing in health and disease.
    Chen YC, Taylor AJ, Verchere CB.
    Diabetes Obes Metab; 2018 Sep 22; 20 Suppl 2():64-76. PubMed ID: 30230179
    [Abstract] [Full Text] [Related]

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