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Journal Abstract Search

316 related items for PubMed ID: 20107996

  • 1. PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.
    Lee DI, Vahebi S, Tocchetti CG, Barouch LA, Solaro RJ, Takimoto E, Kass DA.
    Basic Res Cardiol; 2010 May; 105(3):337-47. PubMed ID: 20107996
    [Abstract] [Full Text] [Related]

  • 2. cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.
    Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA.
    Circ Res; 2005 Jan 07; 96(1):100-9. PubMed ID: 15576651
    [Abstract] [Full Text] [Related]

  • 3. Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.
    Takimoto E, Belardi D, Tocchetti CG, Vahebi S, Cormaci G, Ketner EA, Moens AL, Champion HC, Kass DA.
    Circulation; 2007 Apr 24; 115(16):2159-67. PubMed ID: 17420342
    [Abstract] [Full Text] [Related]

  • 4. Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil.
    Nagayama T, Zhang M, Hsu S, Takimoto E, Kass DA.
    J Pharmacol Exp Ther; 2008 Aug 24; 326(2):380-7. PubMed ID: 18456872
    [Abstract] [Full Text] [Related]

  • 5. Pressure-overload magnitude-dependence of the anti-hypertrophic efficacy of PDE5A inhibition.
    Nagayama T, Hsu S, Zhang M, Koitabashi N, Bedja D, Gabrielson KL, Takimoto E, Kass DA.
    J Mol Cell Cardiol; 2009 Apr 24; 46(4):560-7. PubMed ID: 19159628
    [Abstract] [Full Text] [Related]

  • 6. Phosphodiesterase 5 restricts NOS3/Soluble guanylate cyclase signaling to L-type Ca2+ current in cardiac myocytes.
    Wang H, Kohr MJ, Traynham CJ, Ziolo MT.
    J Mol Cell Cardiol; 2009 Aug 24; 47(2):304-14. PubMed ID: 19345227
    [Abstract] [Full Text] [Related]

  • 7. Phosphodiesterase 5 inhibition blocks pressure overload-induced cardiac hypertrophy independent of the calcineurin pathway.
    Hsu S, Nagayama T, Koitabashi N, Zhang M, Zhou L, Bedja D, Gabrielson KL, Molkentin JD, Kass DA, Takimoto E.
    Cardiovasc Res; 2009 Feb 01; 81(2):301-9. PubMed ID: 19029137
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.
    Isidori AM, Cornacchione M, Barbagallo F, Di Grazia A, Barrios F, Fassina L, Monaco L, Giannetta E, Gianfrilli D, Garofalo S, Zhang X, Chen X, Xiang YK, Lenzi A, Pellegrini M, Naro F.
    Cardiovasc Res; 2015 Jun 01; 106(3):408-20. PubMed ID: 25852085
    [Abstract] [Full Text] [Related]

  • 9. ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice.
    Das A, Salloum FN, Xi L, Rao YJ, Kukreja RC.
    Am J Physiol Heart Circ Physiol; 2009 May 01; 296(5):H1236-43. PubMed ID: 19286961
    [Abstract] [Full Text] [Related]

  • 10. Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition.
    Koitabashi N, Aiba T, Hesketh GG, Rowell J, Zhang M, Takimoto E, Tomaselli GF, Kass DA.
    J Mol Cell Cardiol; 2010 Apr 01; 48(4):713-24. PubMed ID: 19961855
    [Abstract] [Full Text] [Related]

  • 11. Interaction between phosphodiesterases in the regulation of the cardiac β-adrenergic pathway.
    Zhao CY, Greenstein JL, Winslow RL.
    J Mol Cell Cardiol; 2015 Nov 01; 88():29-38. PubMed ID: 26388264
    [Abstract] [Full Text] [Related]

  • 12. Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases.
    Leroy J, Abi-Gerges A, Nikolaev VO, Richter W, Lechêne P, Mazet JL, Conti M, Fischmeister R, Vandecasteele G.
    Circ Res; 2008 May 09; 102(9):1091-100. PubMed ID: 18369156
    [Abstract] [Full Text] [Related]

  • 13. Cardiac phosphodiesterase 5 (cGMP-specific) modulates beta-adrenergic signaling in vivo and is down-regulated in heart failure.
    Senzaki H, Smith CJ, Juang GJ, Isoda T, Mayer SP, Ohler A, Paolocci N, Tomaselli GF, Hare JM, Kass DA.
    FASEB J; 2001 Aug 09; 15(10):1718-26. PubMed ID: 11481219
    [Abstract] [Full Text] [Related]

  • 14. Natriuretic peptides increase beta1-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition.
    Qvigstad E, Moltzau LR, Aronsen JM, Nguyen CH, Hougen K, Sjaastad I, Levy FO, Skomedal T, Osnes JB.
    Cardiovasc Res; 2010 Mar 01; 85(4):763-72. PubMed ID: 19900965
    [Abstract] [Full Text] [Related]

  • 15. Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition.
    Nishida M, Watanabe K, Sato Y, Nakaya M, Kitajima N, Ide T, Inoue R, Kurose H.
    J Biol Chem; 2010 Apr 23; 285(17):13244-53. PubMed ID: 20177073
    [Abstract] [Full Text] [Related]

  • 16. Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
    Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Götz KR, Nikolaev VO, Vanderper A, Herijgers P, Lobysheva I, Iaccarino G, Hilfiker-Kleiner D, Tavernier G, Langin D, Dessy C, Balligand JL.
    Circulation; 2014 Jan 28; 129(4):451-62. PubMed ID: 24190960
    [Abstract] [Full Text] [Related]

  • 17. Regulation and role of myocyte cyclic GMP-dependent protein kinase-1.
    Kass DA, Takimoto E.
    Proc Natl Acad Sci U S A; 2010 Jun 15; 107(24):E98; author reply E99. PubMed ID: 20498039
    [No Abstract] [Full Text] [Related]

  • 18. Distinct phosphodiesterase 5A-containing compartments allow selective regulation of cGMP-dependent signalling in human arterial smooth muscle cells.
    Wilson LS, Guo M, Umana MB, Maurice DH.
    Cell Signal; 2017 Aug 15; 36():204-211. PubMed ID: 28506928
    [Abstract] [Full Text] [Related]

  • 19. Chronic inhibition of cGMP-specific phosphodiesterase 5 suppresses endoplasmic reticulum stress in heart failure.
    Gong W, Duan Q, Cai Z, Chen C, Ni L, Yan M, Wang X, Cianflone K, Wang DW.
    Br J Pharmacol; 2013 Dec 15; 170(7):1396-409. PubMed ID: 24032459
    [Abstract] [Full Text] [Related]

  • 20. Regulation of phospholamban and troponin-I phosphorylation in the intact rat cardiomyocytes by adrenergic and cholinergic stimuli: roles of cyclic nucleotides, calcium, protein kinases and phosphatases and depolarization.
    Sulakhe PV, Vo XT.
    Mol Cell Biochem; 1995 Dec 15; 149-150():103-26. PubMed ID: 8569720
    [Abstract] [Full Text] [Related]

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