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PUBMED FOR HANDHELDS

Journal Abstract Search


285 related items for PubMed ID: 20117093

  • 1. Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780.
    Wang M, Wu L, Wang L, Xin X.
    Biochem Biophys Res Commun; 2010 Feb 26; 393(1):144-9. PubMed ID: 20117093
    [Abstract] [Full Text] [Related]

  • 2. Pretreatment with the γ-secretase inhibitor DAPT sensitizes drug-resistant ovarian cancer cells to cisplatin by downregulation of Notch signaling.
    Wang M, Ma X, Wang J, Wang L, Wang Y.
    Int J Oncol; 2014 Apr 26; 44(4):1401-9. PubMed ID: 24535252
    [Abstract] [Full Text] [Related]

  • 3. Sequential combination therapy of ovarian cancer with cisplatin and γ-secretase inhibitor MK-0752.
    Chen X, Gong L, Ou R, Zheng Z, Chen J, Xie F, Huang X, Qiu J, Zhang W, Jiang Q, Yang Y, Zhu H, Shi Z, Yan X.
    Gynecol Oncol; 2016 Mar 26; 140(3):537-44. PubMed ID: 26704638
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of gamma-secretase in Notch1 signaling pathway as a novel treatment for ovarian cancer.
    Feng Z, Xu W, Zhang C, Liu M, Wen H.
    Oncotarget; 2017 Jan 31; 8(5):8215-8225. PubMed ID: 28030808
    [Abstract] [Full Text] [Related]

  • 5. Effects of N-[N-(3, 5-difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester (DAPT) on cell proliferation and apoptosis in Ishikawa endometrial cancer cells.
    Mori M, Miyamoto T, Yakushiji H, Ohno S, Miyake Y, Sakaguchi T, Hattori M, Hongo A, Nakaizumi A, Ueda M, Ohno E.
    Hum Cell; 2012 Mar 31; 25(1):9-15. PubMed ID: 22189483
    [Abstract] [Full Text] [Related]

  • 6. [Expression of Notch1, Jagged1 and NICD in epithelial ovarian carcinomas and a preliminary study on the activity of gamma-secretase in epithelial ovarian carcinoma cell lines].
    Feng Z, Wen H, Liao Q.
    Zhonghua Fu Chan Ke Za Zhi; 2014 Oct 31; 49(10):780-6. PubMed ID: 25537253
    [Abstract] [Full Text] [Related]

  • 7. [Notch signaling pathway blocked by gamma-secretase inhibitor and its effect on the growth and apoptosis of SKOV3 cells].
    Lu YL, Xie C.
    Sichuan Da Xue Xue Bao Yi Xue Ban; 2014 Jul 31; 45(4):578-81, 611. PubMed ID: 25286679
    [Abstract] [Full Text] [Related]

  • 8. The COX-2 selective inhibitor-independent COX-2 effect on colon carcinoma cells is associated with the Delta1/Notch1 pathway.
    Zhang H, Ye Y, Bai Z, Wang S.
    Dig Dis Sci; 2008 Aug 31; 53(8):2195-203. PubMed ID: 18320325
    [Abstract] [Full Text] [Related]

  • 9. [Effects of gamma-secretase inhibitor N-(3, 5-difluorophenacetyl-L-alanyl)-S-phenylglycine t-butyl ester on proliferation and differentiation of neural stem cells].
    Cai LZ, Lin L, Hu JS, Zheng ZH.
    Zhonghua Yi Xue Za Zhi; 2008 Feb 19; 88(7):480-3. PubMed ID: 18642791
    [Abstract] [Full Text] [Related]

  • 10. [Effect of DAPT on proliferation and apoptosis of human multiple myeloma cell line RPMI8226].
    Yuan YY, Zeng ZY, Chen JM.
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2012 Aug 19; 20(4):922-5. PubMed ID: 22931655
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of Notch signaling pathway using γ-secretase inhibitor delivered by a low dose of Triton-X100 in cultured oral cancer cells.
    Nasrin A, Hassan M, Ye P.
    Biochem Biophys Res Commun; 2018 Jan 15; 495(3):2118-2124. PubMed ID: 29253571
    [Abstract] [Full Text] [Related]

  • 12. Enhanced angiogenesis promoted by human umbilical mesenchymal stem cell transplantation in stroked mouse is Notch1 signaling associated.
    Zhu J, Liu Q, Jiang Y, Wu L, Xu G, Liu X.
    Neuroscience; 2015 Apr 02; 290():288-99. PubMed ID: 25637797
    [Abstract] [Full Text] [Related]

  • 13. [Expression of Notch intracellular domain in cervical cancer and effect of DAPT on cervical cancer cell].
    Sun XM, Wen HW, Chen CL, Liao QP.
    Zhonghua Fu Chan Ke Za Zhi; 2009 May 02; 44(5):369-73. PubMed ID: 19573314
    [Abstract] [Full Text] [Related]

  • 14. [Expression of Notch3 and Notch intracellular domain in ovarian carcinoma and effect of N-[N-(3,5-difluorophenyl) acetyl-L-alanyl]-S-phenyl glycine t-butyl ester on ovarian carcinoma cell].
    Ma K, Wen HW, Liao QP.
    Zhonghua Fu Chan Ke Za Zhi; 2010 Dec 02; 45(12):921-6. PubMed ID: 21211425
    [Abstract] [Full Text] [Related]

  • 15. Antiproliferative effects of γ-secretase inhibitor, a Notch signalling inhibitor, in multiple myeloma cells and its molecular mechanism of action.
    Hu J, Zhu X, Lu Q.
    J Int Med Res; 2013 Aug 02; 41(4):1017-26. PubMed ID: 23839278
    [Abstract] [Full Text] [Related]

  • 16. Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein.
    Yang T, Arslanova D, Gu Y, Augelli-Szafran C, Xia W.
    Mol Brain; 2008 Nov 04; 1():15. PubMed ID: 18983676
    [Abstract] [Full Text] [Related]

  • 17. In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.
    De Keersmaecker K, Lahortiga I, Mentens N, Folens C, Van Neste L, Bekaert S, Vandenberghe P, Odero MD, Marynen P, Cools J.
    Haematologica; 2008 Apr 04; 93(4):533-42. PubMed ID: 18322257
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of gamma-secretases alters both proliferation and differentiation of mesenchymal stem cells.
    Vujovic S, Henderson SR, Flanagan AM, Clements MO.
    Cell Prolif; 2007 Apr 04; 40(2):185-95. PubMed ID: 17472726
    [Abstract] [Full Text] [Related]

  • 19. Xanthohumol decreases Notch1 expression and cell growth by cell cycle arrest and induction of apoptosis in epithelial ovarian cancer cell lines.
    Drenzek JG, Seiler NL, Jaskula-Sztul R, Rausch MM, Rose SL.
    Gynecol Oncol; 2011 Aug 04; 122(2):396-401. PubMed ID: 21616523
    [Abstract] [Full Text] [Related]

  • 20. DAPT enhances the apoptosis of human tongue carcinoma cells.
    Grottkau BE, Chen XR, Friedrich CC, Yang XM, Jing W, Wu Y, Cai XX, Liu YR, Huang YD, Lin YF.
    Int J Oral Sci; 2009 Jun 04; 1(2):81-9. PubMed ID: 20687300
    [Abstract] [Full Text] [Related]


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