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Journal Abstract Search


120 related items for PubMed ID: 20122887

  • 1. Crystal structure of Schistosoma purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor.
    Pereira HM, Berdini V, Ferri MR, Cleasby A, Garratt RC.
    Acta Trop; 2010 May; 114(2):97-102. PubMed ID: 20122887
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  • 2. Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.
    Luić M, Koellner G, Yokomatsu T, Shibuya S, Bzowska A.
    Acta Crystallogr D Biol Crystallogr; 2004 Aug; 60(Pt 8):1417-24. PubMed ID: 15272165
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  • 4. Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue.
    Pereira HM, Berdini V, Cleasby A, Garratt RC.
    FEBS Lett; 2007 Oct 30; 581(26):5082-6. PubMed ID: 17927987
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  • 8. Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase.
    Toms AV, Wang W, Li Y, Ganem B, Ealick SE.
    Acta Crystallogr D Biol Crystallogr; 2005 Nov 30; 61(Pt 11):1449-58. PubMed ID: 16239721
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  • 9. Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies.
    Castilho MS, Postigo MP, Pereira HM, Oliva G, Andricopulo AD.
    Bioorg Med Chem; 2010 Feb 15; 18(4):1421-7. PubMed ID: 20129792
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  • 10. Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis.
    Pereira HD, Franco GR, Cleasby A, Garratt RC.
    J Mol Biol; 2005 Oct 28; 353(3):584-99. PubMed ID: 16182308
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  • 11. Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
    Tebbe J, Bzowska A, Wielgus-Kutrowska B, Schröder W, Kazimierczuk Z, Shugar D, Saenger W, Koellner G.
    J Mol Biol; 1999 Dec 17; 294(5):1239-55. PubMed ID: 10600382
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  • 12. Discovery of new inhibitors of Schistosoma mansoni PNP by pharmacophore-based virtual screening.
    Postigo MP, Guido RV, Oliva G, Castilho MS, da R Pitta I, de Albuquerque JF, Andricopulo AD.
    J Chem Inf Model; 2010 Sep 27; 50(9):1693-705. PubMed ID: 20695479
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  • 14. 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state.
    Chojnowski G, Breer K, Narczyk M, Wielgus-Kutrowska B, Czapinska H, Hashimoto M, Hikishima S, Yokomatsu T, Bochtler M, Girstun A, Staroń K, Bzowska A.
    Biochem Biophys Res Commun; 2010 Jan 01; 391(1):703-8. PubMed ID: 19944078
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  • 16. Crystal structure and molecular dynamics studies of human purine nucleoside phosphorylase complexed with 7-deazaguanine.
    Caceres RA, Timmers LF, Pauli I, Gava LM, Ducati RG, Basso LA, Santos DS, de Azevedo WF.
    J Struct Biol; 2010 Mar 01; 169(3):379-88. PubMed ID: 19932753
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  • 17. Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism.
    Koellner G, Bzowska A, Wielgus-Kutrowska B, Luić M, Steiner T, Saenger W, Stepiński J.
    J Mol Biol; 2002 Jan 18; 315(3):351-71. PubMed ID: 11786017
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