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Journal Abstract Search


74 related items for PubMed ID: 20135639

  • 1. Metabolism of the major Echinacea alkylamide N-isobutyldodeca-2E,4E,8Z,10Z-tetraenamide by human recombinant cytochrome P450 enzymes and human liver microsomes.
    Toselli F, Matthias A, Bone KM, Gillam EM, Lehmann RP.
    Phytother Res; 2010 Aug; 24(8):1195-201. PubMed ID: 20135639
    [Abstract] [Full Text] [Related]

  • 2. Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes.
    Matthias A, Gillam EM, Penman KG, Matovic NJ, Bone KM, De Voss JJ, Lehmann RP.
    Chem Biol Interact; 2005 Jun 30; 155(1-2):62-70. PubMed ID: 15885678
    [Abstract] [Full Text] [Related]

  • 3. Cytochrome P450 inhibitory action of Echinacea preparations differs widely and co-varies with alkylamide content.
    Modarai M, Gertsch J, Suter A, Heinrich M, Kortenkamp A.
    J Pharm Pharmacol; 2007 Apr 30; 59(4):567-73. PubMed ID: 17430641
    [Abstract] [Full Text] [Related]

  • 4. Echinacea metabolism and drug interactions: the case for standardization of a complementary medicine.
    Toselli F, Matthias A, Gillam EM.
    Life Sci; 2009 Jul 17; 85(3-4):97-106. PubMed ID: 19427870
    [Abstract] [Full Text] [Related]

  • 5. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
    Yao HT, Wu YS, Chang YW, Hsieh HP, Chen WC, Lan SJ, Chen CT, Chao YS, Chang L, Sun HY, Yeh TK.
    Drug Metab Dispos; 2007 Jul 17; 35(7):1042-9. PubMed ID: 17403915
    [Abstract] [Full Text] [Related]

  • 6. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H, Guo Z, Persmark M, Mimura M, Inoue K, Guengerich FP, Shimada T.
    Mol Pharmacol; 1994 Sep 17; 46(3):568-77. PubMed ID: 7935340
    [Abstract] [Full Text] [Related]

  • 7. In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes.
    Fang J, McKay G, Song J, Remillrd A, Li X, Midha K.
    Drug Metab Dispos; 2001 Dec 17; 29(12):1638-43. PubMed ID: 11717183
    [Abstract] [Full Text] [Related]

  • 8. Alkylamides from echinacea modulate induced immune responses in macrophages.
    Matthias A, Banbury L, Stevenson LM, Bone KM, Leach DN, Lehmann RP.
    Immunol Invest; 2007 Dec 17; 36(2):117-30. PubMed ID: 17365014
    [Abstract] [Full Text] [Related]

  • 9. Liver enzyme-mediated oxidation of Echinacea purpurea alkylamides: production of novel metabolites and changes in immunomodulatory activity.
    Cech NB, Tutor K, Doty BA, Spelman K, Sasagawa M, Raner GM, Wenner CA.
    Planta Med; 2006 Dec 17; 72(15):1372-7. PubMed ID: 17054047
    [Abstract] [Full Text] [Related]

  • 10. Influence of N-substitution of 7-methoxy-4-(aminomethyl)-coumarin on cytochrome P450 metabolism and selectivity.
    Venhorst J, Onderwater RC, Meerman JH, Commandeur JN, Vermeulen NP.
    Drug Metab Dispos; 2000 Dec 17; 28(12):1524-32. PubMed ID: 11095593
    [Abstract] [Full Text] [Related]

  • 11. Prediction of human liver microsomal oxidations of 7-ethoxycoumarin and chlorzoxazone with kinetic parameters of recombinant cytochrome P-450 enzymes.
    Shimada T, Tsumura F, Yamazaki H.
    Drug Metab Dispos; 1999 Nov 17; 27(11):1274-80. PubMed ID: 10534312
    [Abstract] [Full Text] [Related]

  • 12. Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes.
    Li W, Liu Y, He YQ, Zhang JW, Gao Y, Ge GB, Liu HX, Huo H, Liu HT, Wang LM, Sun J, Wang Q, Yang L.
    Xenobiotica; 2008 Dec 17; 38(12):1551-65. PubMed ID: 18982531
    [Abstract] [Full Text] [Related]

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  • 15. Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.
    Gallagher EP, Wienkers LC, Stapleton PL, Kunze KL, Eaton DL.
    Cancer Res; 1994 Jan 01; 54(1):101-8. PubMed ID: 8261428
    [Abstract] [Full Text] [Related]

  • 16. In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s.
    Prueksaritanont T, Gorham LM, Ma B, Liu L, Yu X, Zhao JJ, Slaughter DE, Arison BH, Vyas KP.
    Drug Metab Dispos; 1997 Oct 01; 25(10):1191-9. PubMed ID: 9321523
    [Abstract] [Full Text] [Related]

  • 17. Oxidative metabolism of the alkaloid rutaecarpine by human cytochrome P450.
    Ueng YF, Don MJ, Jan WC, Wang SY, Ho LK, Chen CF.
    Drug Metab Dispos; 2006 May 01; 34(5):821-7. PubMed ID: 16501007
    [Abstract] [Full Text] [Related]

  • 18. CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver.
    Dehal SS, Kupfer D.
    Cancer Res; 1997 Aug 15; 57(16):3402-6. PubMed ID: 9270005
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of 2-amino-alpha-carboline. A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2.
    Raza H, King RS, Squires RB, Guengerich FP, Miller DW, Freeman JP, Lang NP, Kadlubar FF.
    Drug Metab Dispos; 1996 Apr 15; 24(4):395-400. PubMed ID: 8801053
    [Abstract] [Full Text] [Related]

  • 20. Metabolism of vanoxerine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine, by human cytochrome P450 enzymes.
    Cherstniakova SA, Bi D, Fuller DR, Mojsiak JZ, Collins JM, Cantilena LR.
    Drug Metab Dispos; 2001 Sep 15; 29(9):1216-20. PubMed ID: 11502731
    [Abstract] [Full Text] [Related]


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