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Journal Abstract Search

280 related items for PubMed ID: 20137957

  • 1. Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists.
    Rodríguez-Borges JE, García-Mera X, Balo MC, Brea J, Caamaño O, Fernández F, López C, Loza MI, Nieto MI.
    Bioorg Med Chem; 2010 Mar 01; 18(5):2001-9. PubMed ID: 20137957
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  • 3. 1,3-dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships.
    Fernández F, Caamaño O, Isabel Nieto M, López C, García-Mera X, Stefanachi A, Nicolotti O, Isabel Loza M, Brea J, Esteve C, Segarra V, Vidal B, Carotti A.
    Bioorg Med Chem; 2009 May 15; 17(10):3618-29. PubMed ID: 19398343
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  • 5. Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.
    Baraldi PG, Tabrizi MA, Preti D, Bovero A, Romagnoli R, Fruttarolo F, Zaid NA, Moorman AR, Varani K, Gessi S, Merighi S, Borea PA.
    J Med Chem; 2004 Mar 11; 47(6):1434-47. PubMed ID: 14998332
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  • 6. 1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor.
    Stefanachi A, Brea JM, Cadavid MI, Centeno NB, Esteve C, Loza MI, Martinez A, Nieto R, Raviña E, Sanz F, Segarra V, Sotelo E, Vidal B, Carotti A.
    Bioorg Med Chem; 2008 Mar 15; 16(6):2852-69. PubMed ID: 18226909
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  • 7. Synthesis of novel 1-alkyl-8-substituted-3-(3-methoxypropyl) xanthines as putative A(2B) receptor antagonists.
    Nieto MI, Balo MC, Brea J, Caamaño O, Cadavid MI, Fernández F, Mera XG, López C, Rodríguez-Borges JE.
    Bioorg Med Chem; 2009 May 01; 17(9):3426-32. PubMed ID: 19346133
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  • 10. Preparation, properties, reactions, and adenosine receptor affinities of sulfophenylxanthine nitrophenyl esters: toward the development of sulfonic acid prodrugs with peroral bioavailability.
    Yan L, Müller CE.
    J Med Chem; 2004 Feb 12; 47(4):1031-43. PubMed ID: 14761205
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  • 12. Selective human adenosine A3 antagonists based on pyrido[2,1-f]purine-2,4-diones: novel features of hA3 antagonist binding.
    Priego EM, Pérez-Pérez MJ, von Frijtag Drabbe Kuenzel JK, de Vries H, Ijzerman AP, Camarasa MJ, Martín-Santamaría S.
    ChemMedChem; 2008 Jan 12; 3(1):111-9. PubMed ID: 18000937
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  • 14. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
    Pastorin G, Da Ros T, Spalluto G, Deflorian F, Moro S, Cacciari B, Baraldi PG, Gessi S, Varani K, Borea PA.
    J Med Chem; 2003 Sep 25; 46(20):4287-96. PubMed ID: 13678407
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  • 15. 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists.
    Tabrizi MA, Baraldi PG, Preti D, Romagnoli R, Saponaro G, Baraldi S, Moorman AR, Zaid AN, Varani K, Borea PA.
    Bioorg Med Chem; 2008 Mar 01; 16(5):2419-30. PubMed ID: 18077171
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  • 18. Antagonists of the human adenosine A2A receptor. Part 2: Design and synthesis of 4-arylthieno[3,2-d]pyrimidine derivatives.
    Gillespie RJ, Cliffe IA, Dawson CE, Dourish CT, Gaur S, Giles PR, Jordan AM, Knight AR, Lawrence A, Lerpiniere J, Misra A, Pratt RM, Todd RS, Upton R, Weiss SM, Williamson DS.
    Bioorg Med Chem Lett; 2008 May 01; 18(9):2920-3. PubMed ID: 18407496
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  • 20. Discovery of a novel A2B adenosine receptor antagonist as a clinical candidate for chronic inflammatory airway diseases.
    Elzein E, Kalla RV, Li X, Perry T, Gimbel A, Zeng D, Lustig D, Leung K, Zablocki J.
    J Med Chem; 2008 Apr 10; 51(7):2267-78. PubMed ID: 18321039
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