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Journal Abstract Search

355 related items for PubMed ID: 20156325

  • 1. A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis.
    van der Kraan PM, Blaney Davidson EN, van den Berg WB.
    Arthritis Res Ther; 2010; 12(1):201. PubMed ID: 20156325
    [Abstract] [Full Text] [Related]

  • 2. Age-related alterations in TGF beta signaling as a causal factor of cartilage degeneration in osteoarthritis.
    van der Kraan PM.
    Biomed Mater Eng; 2014; 24(1 Suppl):75-80. PubMed ID: 24928920
    [Abstract] [Full Text] [Related]

  • 3. Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
    Blaney Davidson EN, Remst DF, Vitters EL, van Beuningen HM, Blom AB, Goumans MJ, van den Berg WB, van der Kraan PM.
    J Immunol; 2009 Jun 15; 182(12):7937-45. PubMed ID: 19494318
    [Abstract] [Full Text] [Related]

  • 4. Age-dependent alteration of TGF-β signalling in osteoarthritis.
    van der Kraan PM, Goumans MJ, Blaney Davidson E, ten Dijke P.
    Cell Tissue Res; 2012 Jan 15; 347(1):257-65. PubMed ID: 21638205
    [Abstract] [Full Text] [Related]

  • 5. Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli.
    Hodgson D, Rowan AD, Falciani F, Proctor CJ.
    PLoS Comput Biol; 2019 Jan 15; 15(1):e1006685. PubMed ID: 30677026
    [Abstract] [Full Text] [Related]

  • 6. Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells.
    de Kroon LM, Narcisi R, Blaney Davidson EN, Cleary MA, van Beuningen HM, Koevoet WJ, van Osch GJ, van der Kraan PM.
    PLoS One; 2015 Jan 15; 10(12):e0146124. PubMed ID: 26720610
    [Abstract] [Full Text] [Related]

  • 7. Physiological and excessive mechanical compression of articular cartilage activates Smad2/3P signaling.
    Madej W, van Caam A, Blaney Davidson EN, van der Kraan PM, Buma P.
    Osteoarthritis Cartilage; 2014 Jul 15; 22(7):1018-25. PubMed ID: 24795273
    [Abstract] [Full Text] [Related]

  • 8. Cripto favors chondrocyte hypertrophy via TGF-β SMAD1/5 signaling during development of osteoarthritis.
    Garcia de Vinuesa A, Sanchez-Duffhues G, Blaney-Davidson E, van Caam A, Lodder K, Ramos Y, Kloppenburg M, Meulenbelt I, van der Kraan P, Goumans MJ, Ten Dijke P.
    J Pathol; 2021 Nov 15; 255(3):330-342. PubMed ID: 34357595
    [Abstract] [Full Text] [Related]

  • 9. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.
    Goumans MJ, Valdimarsdottir G, Itoh S, Lebrin F, Larsson J, Mummery C, Karlsson S, ten Dijke P.
    Mol Cell; 2003 Oct 15; 12(4):817-28. PubMed ID: 14580334
    [Abstract] [Full Text] [Related]

  • 10. TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-dependent in primary chondrocytes and mediated by TAK1 kinase activity.
    van Caam A, Madej W, Garcia de Vinuesa A, Goumans MJ, Ten Dijke P, Blaney Davidson E, van der Kraan P.
    Arthritis Res Ther; 2017 May 31; 19(1):112. PubMed ID: 28569204
    [Abstract] [Full Text] [Related]

  • 11. CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes.
    Deroyer C, Charlier E, Neuville S, Malaise O, Gillet P, Kurth W, Chariot A, Malaise M, de Seny D.
    Cell Death Dis; 2019 Feb 04; 10(2):103. PubMed ID: 30718510
    [Abstract] [Full Text] [Related]

  • 12. Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes.
    Finnson KW, Parker WL, Chi Y, Hoemann CD, Goldring MB, Antoniou J, Philip A.
    Osteoarthritis Cartilage; 2010 Nov 04; 18(11):1518-27. PubMed ID: 20833252
    [Abstract] [Full Text] [Related]

  • 13. ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.
    Finnson KW, Parker WL, ten Dijke P, Thorikay M, Philip A.
    J Bone Miner Res; 2008 Jun 04; 23(6):896-906. PubMed ID: 18333754
    [Abstract] [Full Text] [Related]

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  • 15. TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?
    Blaney Davidson EN, van Caam AP, Vitters EL, Bennink MB, Thijssen E, van den Berg WB, Koenders MI, van Lent PL, van de Loo FA, van der Kraan PM.
    Osteoarthritis Cartilage; 2015 Mar 04; 23(3):478-86. PubMed ID: 25529198
    [Abstract] [Full Text] [Related]

  • 16.
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  • 17. Dual roles of misshapen/NIK-related kinase (MINK1) in osteoarthritis subtypes through the activation of TGFβ signaling.
    Yu D, Hu J, Sheng Z, Fu G, Wang Y, Chen Y, Pan Z, Zhang X, Wu Y, Sun H, Dai J, Lu L, Ouyang H.
    Osteoarthritis Cartilage; 2020 Jan 04; 28(1):112-121. PubMed ID: 31647983
    [Abstract] [Full Text] [Related]

  • 18. Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
    Wang Q, Tan QY, Xu W, Qi HB, Chen D, Zhou S, Ni ZH, Kuang L, Guo JY, Huang JL, Wang XX, Wang ZQ, Su N, Chen L, Chen B, Jiang WL, Gao Y, Chen HG, Du XL, Xie YL, Chen L.
    Osteoarthritis Cartilage; 2017 Nov 04; 25(11):1868-1879. PubMed ID: 28716756
    [Abstract] [Full Text] [Related]

  • 19. Insights on biology and pathology of HIF-1α/-2α, TGFβ/BMP, Wnt/β-catenin, and NF-κB pathways in osteoarthritis.
    Wu L, Huang X, Li L, Huang H, Xu R, Luyten W.
    Curr Pharm Des; 2012 Nov 04; 18(22):3293-312. PubMed ID: 22646092
    [Abstract] [Full Text] [Related]

  • 20. Expression of TGFβ-family signalling components in ageing cartilage: age-related loss of TGFβ and BMP receptors.
    van Caam A, Madej W, Thijssen E, Garcia de Vinuesa A, van den Berg W, Goumans MJ, Ten Dijke P, Blaney Davidson E, van der Kraan PM.
    Osteoarthritis Cartilage; 2016 Jul 04; 24(7):1235-45. PubMed ID: 26975812
    [Abstract] [Full Text] [Related]

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