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Journal Abstract Search

135 related items for PubMed ID: 20158183

  • 1. Direct determination of the insulin-insulin receptor interface using transferred cross-saturation experiments.
    Nakamura T, Takahashi H, Takahashi M, Shimba N, Suzuki E, Shimada I.
    J Med Chem; 2010 Mar 11; 53(5):1917-22. PubMed ID: 20158183
    [Abstract] [Full Text] [Related]

  • 2. How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.
    Huang K, Xu B, Hu SQ, Chu YC, Hua QX, Qu Y, Li B, Wang S, Wang RY, Nakagawa SH, Theede AM, Whittaker J, De Meyts P, Katsoyannis PG, Weiss MA.
    J Mol Biol; 2004 Aug 06; 341(2):529-50. PubMed ID: 15276842
    [Abstract] [Full Text] [Related]

  • 3. A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor alpha-chain C-terminal peptide and the site 1 insulin mimetic peptides.
    Menting JG, Ward CW, Margetts MB, Lawrence MC.
    Biochemistry; 2009 Jun 16; 48(23):5492-500. PubMed ID: 19459609
    [Abstract] [Full Text] [Related]

  • 4. Structural insights into ligand-induced activation of the insulin receptor.
    Ward C, Lawrence M, Streltsov V, Garrett T, McKern N, Lou MZ, Lovrecz G, Adams T.
    Acta Physiol (Oxf); 2008 Jan 16; 192(1):3-9. PubMed ID: 18171424
    [Abstract] [Full Text] [Related]

  • 5. Importance of the solvent-exposed residues of the insulin B chain alpha-helix for receptor binding.
    Glendorf T, Sørensen AR, Nishimura E, Pettersson I, Kjeldsen T.
    Biochemistry; 2008 Apr 22; 47(16):4743-51. PubMed ID: 18376848
    [Abstract] [Full Text] [Related]

  • 6. Molecular mechanisms of differential intracellular signaling from the insulin receptor.
    Jensen M, De Meyts P.
    Vitam Horm; 2009 Apr 22; 80():51-75. PubMed ID: 19251034
    [Abstract] [Full Text] [Related]

  • 7. The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix.
    Olsen HB, Ludvigsen S, Kaarsholm NC.
    J Mol Biol; 1998 Nov 27; 284(2):477-88. PubMed ID: 9813131
    [Abstract] [Full Text] [Related]

  • 8. Characterization of a second ligand binding site of the insulin receptor.
    Hao C, Whittaker L, Whittaker J.
    Biochem Biophys Res Commun; 2006 Aug 18; 347(1):334-9. PubMed ID: 16814253
    [Abstract] [Full Text] [Related]

  • 9. Structural basis for the regulation of insulin-like growth factors by IGF binding proteins.
    Siwanowicz I, Popowicz GM, Wisniewska M, Huber R, Kuenkele KP, Lang K, Engh RA, Holak TA.
    Structure; 2005 Jan 18; 13(1):155-67. PubMed ID: 15642270
    [Abstract] [Full Text] [Related]

  • 10. Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor.
    Ward CW, Lawrence MC.
    Bioessays; 2009 Apr 18; 31(4):422-34. PubMed ID: 19274663
    [Abstract] [Full Text] [Related]

  • 11. The high resolution solution structure of the insulin monomer determined by NMR.
    Kaarsholm NC, Ludvigsen S.
    Receptor; 1995 Apr 18; 5(1):1-8. PubMed ID: 7613479
    [Abstract] [Full Text] [Related]

  • 12. Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor.
    Xu B, Hu SQ, Chu YC, Huang K, Nakagawa SH, Whittaker J, Katsoyannis PG, Weiss MA.
    Biochemistry; 2004 Jul 06; 43(26):8356-72. PubMed ID: 15222748
    [Abstract] [Full Text] [Related]

  • 13. Kinetic evidence for the sequential association of insulin binding sites 1 and 2 to the insulin receptor and the influence of receptor isoform.
    Thorsøe KS, Schlein M, Steensgaard DB, Brandt J, Schluckebier G, Naver H.
    Biochemistry; 2010 Jul 27; 49(29):6234-46. PubMed ID: 20568733
    [Abstract] [Full Text] [Related]

  • 14. Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues.
    Wan Z, Xu B, Huang K, Chu YC, Li B, Nakagawa SH, Qu Y, Hu SQ, Katsoyannis PG, Weiss MA.
    Biochemistry; 2004 Dec 28; 43(51):16119-33. PubMed ID: 15610006
    [Abstract] [Full Text] [Related]

  • 15. Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin Wakayama.
    Wan ZL, Huang K, Xu B, Hu SQ, Wang S, Chu YC, Katsoyannis PG, Weiss MA.
    Biochemistry; 2005 Apr 05; 44(13):5000-16. PubMed ID: 15794638
    [Abstract] [Full Text] [Related]

  • 16. Re-engineering the target specificity of the insulin receptor by modification of a PTB domain binding site.
    van der Geer P, Wiley S, Pawson T.
    Oncogene; 1999 May 20; 18(20):3071-5. PubMed ID: 10340378
    [Abstract] [Full Text] [Related]

  • 17. Complex with a phage display-derived peptide provides insight into the function of insulin-like growth factor I.
    Schaffer ML, Deshayes K, Nakamura G, Sidhu S, Skelton NJ.
    Biochemistry; 2003 Aug 12; 42(31):9324-34. PubMed ID: 12899619
    [Abstract] [Full Text] [Related]

  • 18. Insulin and its receptor: structure, function and evolution.
    De Meyts P.
    Bioessays; 2004 Dec 12; 26(12):1351-62. PubMed ID: 15551269
    [Abstract] [Full Text] [Related]

  • 19. A structural switch in a mutant insulin exposes key residues for receptor binding.
    Ludvigsen S, Olsen HB, Kaarsholm NC.
    J Mol Biol; 1998 May 29; 279(1):1-7. PubMed ID: 9636695
    [Abstract] [Full Text] [Related]

  • 20. Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
    Weiss MA, Wan Z, Zhao M, Chu YC, Nakagawa SH, Burke GT, Jia W, Hellmich R, Katsoyannis PG.
    J Mol Biol; 2002 Jan 11; 315(2):103-11. PubMed ID: 11779231
    [Abstract] [Full Text] [Related]

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